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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit September 16, 2015

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SLAS Webinar Sept. 30: Introduction to Gene Editing for Drug Discovery — Pooled Genetic Screens
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John Doench, research scientist in the Broad Institute's RNAi Platform, provides an overview to genome engineering applications in drug discovery with an emphasis on the rapidly developing CRISPR/Cas9 technology platform.

“I love technology development,” says Doench in a recent SLAS e-zine article. "My job is to work with experts in infectious diseases, cancer biology, neurobiology and other areas who want to solve specific biological problems. I apply the latest genome perturbation tools, such as CRISPR, to their model system and, working together, we learn which genes are involved in their particular disease processes."

The Sept. 30 SLAS Webinar is presented by JALA and JBS, the official journals of SLAS, and is free to SLAS dues-paying members. Doench also is co-instructor for an SLAS2016 Short Course, Gene Editing for Drug Discovery.
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SLAS2016 Tony B. Academic Travel Award Applications/Poster Abstracts Due Sept. 21
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Tony B. Awards provide qualifying students with airfare, full conference registration, hotel accommodations and the opportunity to participate fully in SLAS2016, Jan. 23-27 in San Diego, CA. This helpful program honors the late Tony Beugelsdijk by recognizing and assisting up-and-coming researchers who demonstrate outstanding achievement in life sciences R&D. 56 students from 12 countries attended SLAS2015 as Tony B. Academic Travel Award winners. More


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Due Oct. 1: Nominations for The 2016 JALA TEN
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What technological breakthrough has dazzled your mind this year? Nominate it for The 2016 JALA Ten, which recognizes achievements that impact the ability to address key biological and medical issues.

The 2015 JALA Ten included Chad Mirkin's work at Northwestern University, which demonstrated that spherical nucleic acid nanoparticles are capable of crossing the blood-brain barrier and delivering RNA interference therapy against a difficult-to-treat cancer; and IBM’s Dharmendra Modha and the global SyNAPSE group demonstrating the potential of bio-inspired computing in the form of a single chip that contains 1 million neurons and 256 million configurable synapses. SLAS members and nonmembers may be nominated, and self-nominations are welcome.
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Applications Due Oct. 9 for SLAS2016 Innovation AveNEW
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If you are part of a start-up company in life sciences R&D, you are invited to apply for complimentary exhibit space on SLAS2016 Innovation AveNEW, Jan. 23-27, San Diego. This program allows entrepreneurial companies the opportunity to actively engage in a world-class exhibition and connect with thousands of practicing scientists and purchasing decision-makers from leading scientific organizations from more than 40 countries.

Companies whose applications are accepted are provided with no cost kiosk space in the SLAS2016 Exhibition; registration, travel and lodging for one company representative; and the chance to participate in the popular "Late Night with LRIG: Rapid-Fire Innovation" session. Applications are due Oct. 9, 2015.
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SLAS ELN Reports: The Lab Man Interview with SLAS Journals Editors
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JALA Editor-in-Chief Edward Kai-Hua Chow, Ph.D., and JBS Editor-in-Chief Robert M. Campbell, Ph.D., discuss the evolution, editorial focus and unwavering commitment to high quality scientific publishing in this 20th anniversary year for both SLAS journals.

According to Campbell, the journals successfully publish "quality work, work that’s of value and relevance" because of the "passion we have for the science and the excitement and enthusiasm we have for innovation and innovative science." Experience that quality — visit JALA Online and JBS Online today.
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Just Run for the FUNd of It!
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An early morning adventure waits along the San Diego waterfront on Jan. 25 at SLAS2016. This non-competitive get-up-and-go outing is open to all who are interested. Those who make a $25 tax-deductible donation, that benefits the SLAS Graduate Education Fellowship Grant Program, will receive a commemorative T-shirt.

Launched this year, the SLAS Graduate Education Fellowship Grant Program supports students pursuing graduate degrees related to quantitative biosciences and/or life sciences research by way of a $50,000 annual scholarship fund.
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Designer Molecule Shines a Spotlight on Mysterious Four-Stranded DNA
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A small fluorescent molecule has shed new light on knots of DNA thought to play a role in regulating how genes are switched on and off. DNA is typically arranged in a double helix, where two strands are intertwined like a coiled ladder, but previous research has shown the existence of unusual DNA structures called quadruplexes, where four strands are arranged in the form of little knots. More


'Lab-on-a-Chip' Technology to Cut Costs of Sophisticated Tests for Diseases and Disorders
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Engineers have developed a breakthrough device that can significantly reduce the cost of sophisticated lab tests for medical disorders and diseases, such as HIV, Lyme disease and syphilis. The new device uses miniaturized channels and valves to replace "benchtop" assays — tests that require large samples of blood or other fluids and expensive chemicals that lab technicians manually mix in trays of tubes or plastic plates with cup-like depressions. More




New Protein Manufacturing Process Unveiled
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers from Northwestern University and Yale University have developed a user-friendly technology to help scientists understand how proteins work and fix them when they are broken. Such knowledge could pave the way for new drugs for a myriad of diseases, including cancer. The human body has a nifty way of turning its proteins on and off to alter their function and activity in cells: phosphorylation, the reversible attachment of phosphate groups to proteins. More


Praxis, Performance, and Peculiarities of Ultrafast Chiral Liquid Chromatography with Superficially Porous Particles
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A variety of brush-type chiral stationary phases (CSPs) were developed using superficially porous particles (SPPs). Given their high efficiencies and relatively low back pressures, columns containing these particles were particularly advantageous for ultrafast "chiral" separations in the 4–40 s range. Further, they were used in all mobile phase modes and with high flow rates and pressures to separate over 60 pairs of enantiomers. More


Tide Shifting on Embryo Gene Editing?
The Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Ever since researchers in China published a Protein & Cell paper this April detailing their use of CRISPR/Cas9 gene editing in early human embryos, a debate over the bioethics of such work has been raging. The National Institutes of Health quickly issued a statement indicating that it would not fund such research in humans, but some life scientists disagreed. More


New Method To Treat Antibiotic Resistant MRSA: Bacteriophages
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MRSA is bad news. It's a nasty bacterial infection and it can cause serious disease and death. Senior molecular biology major Jacob Hatch knows MRSA as the infection that took his dad’s leg. Hatch, a Brigham Young University student, was thousands of miles away on an LDS mission when Methicillin-Resistant Staphylococcus Aureus decalcified the bones in his dad's foot and lower leg, leading to an emergency amputation just below the knee. More


Evidence for Human Transmission of Alzheimer's Pathology?
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In short order, the news media will be flooded with sensational headlines and Twitter feeds will be flurried with questions of how someone can catch the new "transmissible" strain of Alzheimer's disease. While previous evidence has shown that transplantation of specific tissues can mildly recapitulate the symptoms of AD between animals, no evidence of iatrogenic transmission in humans has been observed. More


Career


Research Associate – Automation Core
Cell Signaling Technology, Inc.
US – MA – Danvers

Research Associate, Quality Control
New York Stem Cell Foundation
US – NY – NY

NGS Automation Engineer
Kapa Biosystems
US – MA – Boston

More jobs at SLAS Career Connections


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