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  Mobile version   RSS   Subscribe   Unsubscribe   Archive   Media Kit Sep. 19, 2012

SLAS.org    SLAS2013    Moving? New job? Let SLAS know.    


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Discussions and musings focused on the engaging field of laboratory science and technology.


 
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2013 JALA Ten: Just four more days to submit nominations!
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Nominate yourself, or nominate a colleague, but do so by Sept. 22! The JALA Editorial Board wants to hear about top technological breakthroughs that you feel have had a profound impact on the general fields of biology and medicine this past year. Need some inspiration? Take a look at last year's JALA Ten. More

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Are you interested in a leadership role with SLAS?
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Upon her election to the 2012 SLAS Board of Directors, Robyn Rourick said, "I look forward to the privilege of helping to drive greater reach, impact and success of science through laboratory technology collaboratively with a pristine group of dedicated and talented individuals." Submit your name to the SLAS Nominations Committee for the 2013 Board of Directors election so you can join Robyn in her quest. But act fast! Materials are due by midnight CDT Monday, Oct. 1. More



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Register for Sept. 27 webinar — FREE for SLAS members
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"One of the big challenges is that compared to a lot of conventional assays where you might look at one or two measurements, high-content assays can typically give anywhere from tens to hundreds of measurements from a single well," says Donald G. Jackson, Ph.D., Bristol-Myers Squibb Research & Development. In the Sept. 27 webinar, Jackson discusses novel data management and analysis tools to address these data needs using a combination of internally developed solutions, commercial and open source software. "Data Management, Analysis and Visualization Tools for Understanding Multidimensional Screening Results," begins at 11:30 a.m. EDT and lasts one hour. More

LinkedIn: a job seeker's new best friend
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Learn about personal branding and intelligent network building to increase career opportunities in "Your Resume on Steroids: Using LinkedIn to Get a Job" on SLAS Electronic Laboratory Neighborhood. "Invest in LinkedIn now for the long-term," says Liming Shi, chair of the SLAS Technology Transfer and CRO/CMO Project Management Special Interest Group and LinkedIn advocate. "Get yourself up and running, so if and when you really need it, it will be ready and you'll be able to mobilize quickly." The SLAS ELN feature previews SLAS2013 workshops by Wayne Breitbarth, author of The Power Formula for LinkedIn Success: Kick-start Your Business, Brand and Job Search. More


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How to get your employer to approve your participation in SLAS2013
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Don't just ask the powers that be to approve your trip to SLAS2013, Jan. 12-16 in Orlando, Fla. Instead, present them with a sound business case that rationally justifies your participation by illustrating the benefits they can expect to receive in return for their investment. Keep your employer's priorities in focus, and do not presume that your employer will automatically recognize what appears to you as intrinsic value. Be as specific as possible, and give examples. Also, register by Oct. 31 to minimize your costs. More

JALA Online features new manuscripts ahead-of-print
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"The Use of Cold Plasma Technology to Reduce Carryover in Screening Assays," "Conception through Build of an Automated Liquids Processing System for Compound Management in a Low-Humidity Environment" and "High-Throughput Secondary Screening at the Single-Cell Level" are among the new manuscripts available only to SLAS Laboratory Automation Section members ahead of print. More

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Single molecule imaging of oxygenation of cobalt octaethylporphyrin at the solution/solid interface
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
For the first time, the pressure and temperature dependence of a chemical reaction at the solid/solution interface is studied by scanning tunneling microscopy (STM), and thermodynamic data are derived. In particular, the STM is used to study the reversible binding of O2 with cobalt(II) octaethylporphyrin (CoOEP) supported on highly oriented pyrolytic graphite (HOPG) at the phenyloctane/CoOEP/HOPG interface. More

Making effective regenerative medicine decisions
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The field of regenerative medicine (RM), encompassing stem cell (SC) technologies, therapeutics, and tissue engineering (TE) provides a wide gamut of tools to combat, manage and, hopefully, cure serious human and animal injuries, dysfunctions and diseases. Media hype and public expectations combined with divided trends and approaches among scientific, clinical, and business leaders have led to time- and cost-ineffectiveness and unconsolidated outcomes. More


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Scientists develop nose-like device to sniff out cancer cells
Business Standard    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists claim to have developed a sensor array system which can "smell" different cancer types in the same way a human nose can identify and remember different odors. Researchers from the University of Massachusetts Amherst have developed a sensor array system of gold nanoparticles and proteins to detect microscopic levels of many different metastatic cell types in living tissue. More

D-protein inhibits key drug target
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers have used native chemical ligation, mirror-image phage display and racemic protein crystallography to identify the first D-protein antagonist of vascular endothelial growth factor type A (VEGF-A). The work could lead to improved cancer and macular degeneration drugs. Two injectable drugs, the anticancer drug Avastin and the macular degeneration agent Lucentis, are conventional L-protein VEGF-A antagonists. More



Optimizing the sensitivity of photoluminescent probes using time-resolved spectroscopy
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Improving probes so that they can perform more sensitive and accurate detections is at the heart of much fundamental and applied research. Within the past few years a considerable amount of effort has been devoted to the study of photoluminescent probes in combination with time-resolved photoluminescence spectroscopy (TRPS). More

Bipartite tetracysteine display reveals allosteric control of ligand-specific EGFR activation
ACS Chemical Biology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Aberrant activation of the epidermal growth factor receptor (EGFR), a prototypic receptor tyrosine kinase, is critical to the biology of many common cancers. The molecular events that define how EGFR transmits an extracellular ligand binding event through the membrane are not understood. Here we use a chemical tool, bipartite tetracysteine display, to report on ligand-specific conformational changes that link ligand binding and kinase activation for full-length EGFR on the mammalian cell surface. More


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Video: Government wizards levitate drugs with ultrasonic sound
Popular Science    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Good drugs dissolve easily in the body. Bad pharmaceutical molecules, meanwhile, lock themselves into hard-to-absorb crystals that require strong doses to work, and this overcompensation often leads to crummy side effects. Unfortunately, the very lab equipment that pharmaceutical researchers use to create new crystal-free drugs can cause the molecules to crystallize. More

Brain growth depends on shapely neurons
New Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The human brain may be the most complex object in the universe, but its construction mostly depends on one thing: the shape of neurons. Different kinds of neuron are selective about which other neurons they connect to and where they attach. Specific signalling chemicals are thought to be vital in guiding this process. More

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New research could provide new insights into tuberculosis, other diseases
Phys.org    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers Patricia A. Champion and Matthew Champion from the University of Notre Dame's Eck Institute for Global Health have developed a method to directly detect bacterial protein secretion, which could provide new insights into a variety of diseases including tuberculosis. The Champions point out that bacteria use a variety of secretion systems to transport proteins beyond their cell membranes in order to interact with their environment. More

Alpine glaciers contribute to carbon cycling
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists have unraveled the role of Alpine glaciers for carbon cycling. They have uncovered unexpected biogeochemical complexity of dissolved organic matter locked in glaciers and studied its fate for carbon cycling in glacier-fed streams. Their article expands current knowledge on the importance of the vanishing cryosphere for biogeochemistry. More


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Career


Director of Research, Robert B. Daugherty Water for Food Institute
Institute of Agriculture and Natural Resources, University of Nebraska-Lincoln
USA – NE – Lincoln

Tenure Track Position in Nutrition and Food Science
University of Missouri Columbia
USA – MO – Columbia

Post-Doctoral Research Fellow – Statistical Genetics
Fred Hutchinson Cancer Research Center
USA – WA – Seattle

More jobs at SLAS Career Connections


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