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  Mobile version   RSS   Subscribe   Unsubscribe   Archive   Media Kit Sep. 25, 2013

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SLAS e-zine: The New Future of Phenotypic Drug Discovery
SLAS    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A strong voice for phenotypic drug discovery (PDD) has been heard the last couple years within the SLAS community. PDD advocates have been sharing information widely at the SLAS PDD Special Interest Group meeting at the annual conference and through year-round networking on the SLAS Phenotypic Drug Discovery SIG on LinkedIn. The Fall 2013 SLAS Webinar Series tackles the topic beginning Sept. 26. And a two-part JBS special issue distributes Dec. 2013 and Jan. 2014. Learn more about this important topic in the latest SLAS e-zine article featuring David Swinney, Ellen Berg and Jonathan Lee. More

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Nominations due Oct.1 for The 2014 JALA Ten
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Less than a week remains to nominate yourself or a colleague for The 2014 JALA Ten. JALA annually names The JALA Ten to honor the top 10 technological breakthroughs that made significant impact toward addressing key biological and medical quandaries. SLAS members and nonmembers are invited to submit nominations. Read about last year's honorees. More

Innovation AveNEW applications due Oct. 11
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Innovation AveNEW is an in-kind, cost-sensitive program offering emerging, start-up laboratory science and technology companies the opportunity to actively engage and participate in SLAS2014. If selected, SLAS provides kiosk exhibit space, travel, lodging and access to purchasing influencers and decision-makers from more than 40 countries. Read about a few previous SLAS Innovation AveNEW success stories. More

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The man behind conference travel awards for students
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Each year, SLAS invites and encourages students, post-doctoral associates and junior faculty to apply for Tony B. Academic Travel Awards, which provide airfare, shared hotel accommodations and full registration to those selected on the merits of their podium or poster abstract submission. But, who is Tony B? This award honors the late Tony Beugelsdijk, Ph.D., who played an inspirational and instrumental role in laboratory automation, the Society and the scientific community as a whole. Read more about this talented leader and role model in the Journal of Laboratory Automation. More

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Entries due Oct. 18: 2014 JALA & JBS Art of Science Contest
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Visualization plays an important role in the analysis and presentation of scientific work. In journal articles, images often communicate ideas and information in ways that text, tables, charts, graphs or equations cannot. Sometimes scientific images surpass this purpose and create shapes, patterns and designs that capture attention and imagination. These are the images JALA and JBS seek for the 2014 Art of Science Contest. One grand prize winner will receive a $500 Amazon gift card. Nine finalists will receive $25 Amazon gift cards plus 60 days free online access to the SAGE Pharmacology and Biomedical Collection (75,000-plus articles!). Submit your favorite cell structures, assay results or other lab creations today! Read about last year's winners. More

Save on SLAS2014 — Register by Oct. 31
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SLAS members who register by Oct. 31 will save $240 off their registration fee. Be sure to check other discounts for academics, students, groups and the unemployed to participate in the leading event for those in laboratory science and technology. SLAS2014 will be held Jan. 18-22 in San Diego. More


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Brazil says it can't handle World Cup drug testing
The Associated Press    Share    Share on FacebookTwitterShare on LinkedinE-mail article
With one lab suspended and its replacement unfinished, Brazil won't be able to handle drug testing for the 2014 World Cup alone and is looking overseas for help. The executive director of the country's anti-doping authority told The Associated Press the new lab in Rio de Janeiro should be running a year before the 2016 Olympics. But, Marco Aurelio Klein added, the lab won't be ready for the World Cup next June and July. More

Enzymes may be able to protect people from sarin gas, other nerve agents
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Perhaps a million years ago, a protohuman ate a poisonous berry. The berry was loaded with natural organophosphate molecules that probably protected it from insect pests. Unfortunately, those molecules could also wreak havoc on the nervous system of a larger animal, perhaps disabling or killing it. But the human ancestor's blood contained an enzyme known as butyrylcholinesterase, which bound the toxic molecules, rendering them inert. Our forerunner survived. More


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Orthoformimycin, a selective inhibitor of bacterial translation elongation from streptomyces containing an unusual orthoformate
ACS Chemical Biology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Upon high throughput screening of 6700 microbial fermentation extracts, we discovered a compound, designated orthoformimycin, capable of inhibiting protein synthesis in vitro with high efficiency. The molecule, whose structure was elucidated by chemical, spectrometric and spectroscopic methods, contains an unusual orthoformate moiety (hence the name) and belongs to a novel class of translation inhibitors. More

Submillisecond protein folding events monitored by rapid mixing and mass spectrometry-based oxidative labeling
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Kinetic measurements can provide insights into protein folding mechanisms. However, the initial (submillisecond) stages of folding still represent a formidable analytical challenge. A number of ultrarapid triggering techniques have been available for some time, but coupling of these techniques with detection methods that are capable of providing detailed structural information has proven to be difficult. More

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Creating electricity with caged atoms
Phys.org    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Clathrates are crystals consisting of tiny cages in which single atoms can be enclosed. These atoms significantly alter the material properties of the crystal. By trapping cerium atoms in a clathrate, scientists at the Vienna University of Technology have created a material which has extremely strong thermoelectric properties. It can be used to turn waste heat into electricity. A lot of energy is wasted when machines turn hot, unnecessarily heating up their environment. More

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Theory and formula to improve 'plastic' semiconductors developed
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Anyone who's stuffed a smart phone in their back pocket would appreciate the convenience of electronic devices that could bend. Flexible electronics could spawn new products: clothing wired to cool or heat, reading tablets that could fold like newspaper, and so on. Alas, electronic components such as chips, displays and wires are generally made from metals and inorganic semiconductors — materials with physical properties that make them fairly stiff and brittle. More

Herpes virus cleared from blood for first time
New Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A common virus that can reduce lifespan and cause blindness has been cleared from human blood for the first time. Cytomegalovirus, a type of herpes virus, is carried by about 70 percent of people and, although it usually doesn't cause illness, shaves 3.7 years off life expectancy. In people with a weakened immune system, however, the virus awakens and can cause serious illness and blindness. More


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Study brings universal flu vaccine a step closer
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists have moved closer to developing a universal flu vaccine by using the 2009 pandemic to study why some people seem to resist severe illness. Researchers at Imperial College London asked volunteers to donate blood samples just as the swine flu pandemic was getting underway and report any symptoms they experienced over the next two flu seasons. More

Oct. 31 deadline for pharmacology conference
National University of Singapore     Share    Share on FacebookTwitterShare on LinkedinE-mail article
The Yong Loo Lin School of Medicine at the National University of Singapore is now accepting abstracts for its International Conference on Pharmacology and Drug Development, which will be held in Singapore Dec. 9-11, 2013. Symposium speakers and poster presentations will be selected to address pharmacology and its impact on cancer, neuroscience, immunology, cardiovascular biology and more. Keynote speakers include Prof. Shuh Narumiya of Kyoto University, Japan, and Prof. Philip Moore of National University of Singapore. More

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Microfluidic systems for screening of aptamers
Dr. Afsaneh Motamed-Khorasani    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Systematic evolution of ligands by exponential enrichment, or SELEX, is a method to screen the nucleotide ligands from a large library of nucleotide sequences. Aptamers are the nucleotide ligands selected by SELEX method and can be easily and inexpensively produced. Microfluidic devices could provide accurate clinical analysis in less time and could be used for the development of point-of-care devices in the near future. More

Free video tutorials offered
METTLER TOLEDO     Share    Share on FacebookTwitterShare on LinkedinE-mail article
METTLER TOLEDO has recently released a series of new video tutorials for laboratory professionals in academia. These 30-45 minute long videos provide insights into the topics of pipetting, weighing, pH determination and thermal analysis. In addition to the video tutorials, posters and other relevant information and supporting material can also be accessed. These tutorials are designed as a refresher for those working in laboratories, but also as educational material for professors and teachers to be used in classrooms. More



How gut microbes affect your health
Live Science    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Our bodies are teeming with hundreds of distinct kinds of microbes, such as fungi, viruses and bacteria. Early work in understanding our resident microorganisms (microbiota) focused on identifying the many species by mass-sequencing their genomes (metagenomics). Now, attention has turned to understanding exactly how the microbial populations function, thrive and, most importantly, contribute to our health. More

Big Pharma replaces innovation with acquisition
By Mike Wokasch    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Big Pharma, including Big Biotech, has executed about 130 mergers or acquisitions in each of the past couple of years. The overwhelming majority of deals designed to fill depleted Big Pharma pipelines with more novel and innovative technologies in later stages than their own R&D had been able to produce. If Big Pharma is relying on others to do drug discovery, how deep does the discovery pipeline have to go to be indefinitely sustainable? More


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Career


Director Clinical and Translational Research
Entrepreneurial Neonatology Practice
US – NJ – Morristown

Biomedical Automation Senior Scientist
Oregon Translational Research and Development Institute
US – OR – Portland

Senior Research Laboratory Manager, Director of Research Projects
Massachusetts General Hospital
US – MA – Boston

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