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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit October 01, 2014

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Nominations for The 2015 JALA Ten Due Today
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Every year, JALA honors the top 10 technological breakthroughs that made seminal impact toward addressing key biological and medical quandaries. The JALA Ten embraces a spectrum of fields that include but are not limited to laboratory automation, robotics, drug discovery, drug screening, novel therapeutic strategies and delivery technologies, diagnostics, nanotechnology, nanomedicine, microtechnology as it relates to biology and medicine, novel characterization techniques and more. Nominations are due today and are open to SLAS members and nonmembers. Self-nominations are welcome. More

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SLAS Webinar Oct. 7: Making a Quantum Leap in Mass Spectrometry Throughput with Acoustic Dispensing
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This SLAS Webinar beginning at 11:30 a.m. EDT features two presentations. 2013 SLAS Innovation Award Winner Andrea Weston presents "Applying the MassInsight Technology to Monitor CYP Inhibition in Human Liver Microsomes" and Jefferson Chin offers "High-Throughput MALDI Mass Spectrometry for Small Molecule Analysis." Weston and Chin are in Leads Discovery and Optimization at Bristol-Myers Squibb. Dues-paid SLAS members can join the webinar live Oct. 7, or access on demand after the event, for free. Last week's ultra-high throughput flow cytometry SLAS Webinar, which was attended live by nearly 120 viewers, now is available on demand. More

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SLAS ELN Reports: SLAS2015 and the Scientific Coalescence of Industry, Academia and Government
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In his new SLAS Electronic Laboratory Neighborhood e-zine message, SLAS President Daniel G. Sipes reveals opportunities to connect with influential scientific leaders due to the SLAS2015 Washington, D.C. location. These include the keynote address by National Institutes of Health Director Francis Collins and two special sessions. One, "An Evening with the NIH," is led by Christopher Austin, director of the NIH National Center for Advancing Translational Science. The other, "European Government/Foundation Drug Discovery Initiatives" led by SLAS Europe Council Chair Steven Rees, features updates on four programs. More



Congratulations to New SLAS Young Scientist Delegate
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Graduate student Katja-Emilia Lillsunde, University of Helsinki, Finland, was named an SLAS Young Scientist Delegate last week at the MipTec Conference and Exhibition in Basel, Switzerland. The student's winning poster was titled "An Advanced Cellular Assay for Replicon-Based Antiviral Screening of Marine Natural Product." In conjunction with this distinction, Lillsunde receives a $500 cash prize, roundtrip coach airfare, shared hotel accommodations and full conference registration for SLAS2015, Feb. 7-11, 2015, Washington, D.C. More



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    Open Access in JALA: Automated and Online Characterization of Adherent Cell Culture Growth in a Microfabricated Bioreactor
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    A team from University College London reports on the "integration of a previously described microfabricated device with automated image acquisition and processing routines. Requirements and strategies for intermittent and continuous imaging are described. In addition to previously reported human embryonic stem cell colony monitoring capabilities, the image-processing algorithm was further improved to enable the monitoring of long-term on-chip mouse embryonic stem cell cultures. In both cases, cell proliferation was characterized at a population level using confluency while cellular object tracking helped gain an insight into the response of colonies to continuous perfusion." More

    SLAS Board of Directors Candidate Applications Due Oct. 10
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    The SLAS Nominations Committee, chaired by Rich Ellson of Labcyte, is in the process of selecting three individuals who will join the SLAS Board of Directors for three-year terms of service.

    Check the SLAS website for requirements if you are interested in submitting a candidate application.
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    Ingber Team Develops Biospleen for Sepsis Therapy
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    Published online Sept. 14 in Nature Medicine, SLAS2015 Keynote Speaker Donald E. Ingber and team have developed a new device that can cleanse human blood to filter live and dead pathogens, as well as dangerous toxins that are released from the pathogens. The biospleen is a microfluidic device that consists of two adjacent hollow channels that are connected to each other by a series of slits: one channel contains flowing blood, and the other has a saline solution that collects and removes the pathogens that travel through the slits. Key to the success of the device are tiny nanometer-sized magnetic beads that are coated with a genetically engineered version of a natural immune system protein called mannose binding lectin (MBL). Photo credit: Harvard's Wyss Institute. More

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    Routine CHN Microanalysis of Difficult Sample Types
    Exeter Analytical    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    Warwick Analytical Service has developed a range of CHN microanalysis methodologies allowing them to routinely produce precise and accurate percentage carbon, hydrogen and nitrogen data from a range of difficult samples. This information is provided in a new application note detailing the Warwick Analytical methodologies for handling volatile liquids, air sensitive compounds, refractory materials, samples with elemental interferences as well as in homogeous and bulky samples.
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    US Ebola Labs, Parts for Clinic Arrive in Liberia
    Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    The United States military has delivered two mobile Ebola testing labs and the equipment to build a field hospital to Liberia. Liberia has been hardest hit by the Ebola outbreak that has touched four other West African countries. The World Health Organization says more than 3,000 deaths have been linked to the disease in the largest outbreak ever. More

    Top 25 Molecular Millionaires
    Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    CEOs and other executives and relatives with the biggest stakes in biopharma drug development and tools companies saw those stakes grow in value along with the market last year, judging from this year's GEN List of what we call "molecular millionaires." More often than not, the healthiest growth over the past year has been enjoyed by those invested in biotech giants with new products approved and/or launched to market in 2013. More

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    Tips for Establishing Successful Cell-Based Assays: Part 2
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    Standard Cell Culture Practices to Reduce Contamination Risk
    Most laboratories have rules pertaining to blood-born pathogens. These rules may include mandatory training and certification prior to handling cells, human or non-human, primary or transformed. Be sure you know the rules in detail and follow them. The following is a guide for sources of contamination and ways to avoid them. More

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    The Process by which Drugs are Discovered and Developed will be Fundamentally Different in the Future
    Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    Before joining Washington University in St. Louis, Michael Kinch, PhD, was managing director of the Center for Molecular Discovery at Yale University. "A few years ago, to motivate the team I gave them what's called a Big Hairy Audacious Goal (a B-HAG)," Kinch says. The B-HAG was many-headed but one of the heads was to make a collection of all FDA-approved drugs. The idea was that the collection would serve as a screening library for drug repurposing. More

    30 Years of Generics
    Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    In September 1984, the Drug Price Competition & Patent Term Restoration Act, commonly known as the Hatch-Waxman Act for its congressional sponsors' names, was signed into U.S. law. By creating a new regulatory path for generic medicines and launching a new business, the act was a watershed in the history of the pharmaceutical industry. More


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    Hydrogen Production From Ammonia Using Sodium Amide
    Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    This paper presents a new type of process for the cracking of ammonia (NH3) that is an alternative to the use of rare or transition metal catalysts. Effecting the decomposition of NH3 using the concurrent stoichiometric decomposition and regeneration of sodium amide (NaNH2) via sodium metal (Na), this represents a significant departure in reaction mechanism compared with traditional surface catalysts. More

    Protein Map Offers Tips for Novel Cancer Therapy Approaches
    Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    Researchers at Imperial College London say they have gained new insights into how a disease-causing enzyme makes changes to proteins and how it can be stopped. The scientists hope their findings will help them design drugs that could target N-myristoyltransferase and potentially lead to novel therapies for cancer and inflammatory conditions. More



    High-Throughput Cell-Sorting Method Can Separate 10 Billion Bacterial Cells in 30 Minutes
    Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    A new, high-throughput method for sorting cells has been developed, capable of separating 10 billion bacterial cells in 30 minutes. The finding has already proven useful for studying bacterial cells and microalgae, and could one day have direct applications for biomedical research and environmental science — basically any field in which a large quantity of microbial samples need to be processed. More

    Chemists Observe Key Reaction for Producing 'Atmosphere's Detergent'
    Phys.org    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    Earth's atmosphere is a complicated dance of molecules. The chemical output of plants, animals and human industry rise into the air and pair off in sequences of chemical reactions. Such processes help maintain the atmosphere's chemical balance; for example, some break down pollutants emitted from the burning of fossil fuels. More

    Bacteria in Wine May Bring Health Benefits
    Live Science    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    There are bacteria in wine that may be beneficial for people's health, new research finds. In the study, researchers in Spain isolated 11 strains of bacteria from wine, including strains of Lactobacillus, which are also found in yogurt, as well as Oenococcus and Pediococcus bacteria, which are associated with the wine-making process. More


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    US – TN – Memphis

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