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  Mobile version   RSS   Subscribe   Unsubscribe   Archive   Media Kit Oct. 2, 2013    SLAS2014    Moving? New job? Let SLAS know.    







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The SLAS Electronic Laboratory Neighborhood

Interactive e-zine sharing experiences and perspectives on science-related topics. Send article ideas to




SLAS Forms Europe Council
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In his latest column in the SLAS Electronic Laboratory Neighborhood e-zine, SLAS President Jeff Paslay, Ph.D., announces the seven members of the new SLAS Europe Council. This is the first step in deploying a new, decentralized SLAS leadership model that creates regional leadership councils in Europe, Asia and the Americas, which are overseen by the SLAS Board of Directors. Paslay also invites candidate applications by Oct. 11 for the SLAS Board of Directors. More


JALA podcast features Microfluidic Multiplexing in Bioanalyses authors
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JALA Podcast Editor David Pechter talks with JALA October cover authors M. Kursad Araz and Augusto M. Tentori. Their JALA article highlights recent advances in multiplexed bioanalyses benefitting from microfluidic integration and concludes, "Challenges remain since most multiplexed microfluidic assays are in the early research stage, still at the proof-of-principle stage. Clearly, continued innovation coupled with focused development and application to a wider set of applications is on the horizon. In this regard, pursuit of promising approaches to translational gaps is likely to increase the performance, capabilities, and availability of these assay platforms. We look forward to the next decade, in which we will be seeing multiplexed microfluidic assays addressing — in the field—challenging medical and life sciences questions." More

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Congratulations SLAS Young Scientist Delegate!
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Congratulations Eyram Adjogatse! Adjogatse was named SLAS Young Scientist Delegate at MipTec 2013 for his winning poster, “Multiple drug design strategies for the discovery of new treatments for human African trypanosomiasis.” He is a postgraduate researcher in the Laboratory for Protein Crystallography, Division of Medicine, University College London Medical School - Royal Free Campus. Adjogatse receives a $500 cash prize, roundtrip airfare, hotel accommodations and full conference registration for SLAS2014, Jan. 18-22, 2014, San Diego, CA. He is pictured here with his winning poster. Check SLAS Facebook for more photos. More


Spotlight on JALA and JBS cover authors
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When you visit the SLAS Electronic Laboratory Neighborhood e-zine, be sure to read the newest section, SLAS Cover Author Spotlights. Each issue of JALA and JBS features one manuscript on its front cover. The SLAS ELN shines a spotlight on the authors of those manuscripts, sharing a personal profile and related links. For October, the JALA cover author is M. Kursad Araz, co-founder of Correlia Biosystems, Berkeley, CA; and the JBS cover author is Stephen L. Garland, CEO/founder of NQuiX, Stevenage, United Kingdom. More

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David Swinney's phenotypic drug discovery webinar available On-Demand
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If you missed last week's very popular SLAS Webinar, "The Value of Phenotypic-Based Drug Discovery," you can access it anytime through SLAS On-Demand. This highly attended webinar is the first in a three-part SLAS Webinar Series, "Phenotypic and Signaling Network Approaches as an Alternative to Target Based Drug Discovery," sponsored by Cellular Dynamics International. The next webinar in the series is "Phenotypic Drug Discovery Using Primary Human Cells and Co-Cultures: Lessons Learned," led by Ellen L. Berg, scientific director, BioSeek (a division of DiscoveRx). SLAS Webinars are free to dues-paid SLAS members. SLAS BSS members also can read new scientific manuscripts on phenotypic drug discovery ahead-of-print at JBS Online. More

Important SLAS deadlines
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October 11: SLAS2014 Innovation AveNEW applications
October 11: SLAS Board of Directors candidate applications
October 18: 2014 JALA & JBS Art of Science Contest
October 28: SLAS2014 poster abstract submissions and student poster competition
October 31: SLAS2014 early-bird registration deadline

Dualsystems Biotech AG
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Real-Time Monitoring Cell Migration/Invasion
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Add-and-Read Plate Reader
Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.


Peer review: how to get it right — 10 tips
The Guardian    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A professor at Trinity College Dublin offers expert advice on how to be helpful, scientific and professional when reviewing a research paper. "Reviewing is an excellent way to keep up with literature and a superb way to sharpen your own writing." More

Scripps Research Institute study finds new moves in protein's evolution
eBioNews    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Highlighting an important but unexplored area of evolution, scientists at The Scripps Research Institute have found evidence that, over hundreds of millions of years, an essential protein has evolved chiefly by changing how it moves, rather than by changing its basic molecular structure. The work has implications not only for the understanding of protein evolution, but also for the design of antibiotics and other drugs that target the protein in question. More


Hierarchical self-assembly: Well-defined supramolecular nanostructures and metallohydrogels via amphiphilic discrete organoplatinum(II) metallacycles
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Metallacyclic cores provide a scaffold upon which pendant functionalities can be organized to direct the formation of dimensionally controllable nanostructures. Because of the modularity of coordination-driven self-assembly, the properties of a given supramolecular core can be readily tuned, which has a significant effect on the resulting nanostructured material. Herein we report the efficient preparation of two amphiphilic rhomboids that can subsequently order into 0D micelles, 1D nanofibers, or 2D nanoribbons. More

Labcyte announces collaboration with AstraZeneca
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Last week, Labcyte Inc. announced a collaboration with AstraZeneca to use acoustic dispensing combined with mass spectrometry to greatly advance drug discovery applications. Labcyte recently developed techniques for the direct loading of samples into mass spectrometers. This capability creates the potential for high throughput, low cost, label-free analysis. AstraZeneca is supporting this development effort with the goal of expanding mass spectrometry-based analysis throughout the entire drug discovery and development process. More


Enabling systems biology approaches through microfabricated systems
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
With the experimental tools and knowledge that have accrued from a long history of reductionist biology, we can now start to put the pieces together and begin to understand how biological systems function as an integrated whole. Here, we describe how microfabricated tools have demonstrated promise in addressing experimental challenges in throughput, resolution and sensitivity to support systems-based approaches to biological understanding. More

Tweaking Mother Nature's chemistry box    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Natural enzymes are very clever molecular machines. They are the catalyst for many of nature's chemical transformations. And the conditions they need to perform their task are rather precisely defined. There is a need to study enzymes, in order to adapt them as a means to harness their power for industrial scale chemical processes. For example enzymes included in washing machine detergent contribute to helping making the laundry clean. More

Scigilian Software, Inc.
Scigilian is a software company specializing in offering solutions to the problems encountered in pharmaceutical research, biotechnology, and contract research. Trusted, from large pharma to small CRO.
Dualsystems Biotech AG
Dualsystems Biotech is a provider of custom screening services for industry and academia, specializing in yeast two-hybrid, CaptiVate AP/MS-MS and cDNA library construction.

Online instructional robotic technical topics covered by experienced engineering team
Adept Technology     Share    Share on FacebookTwitterShare on LinkedinE-mail article
Adept Technology announced a new "Tech Topics" webinar series targeted at system integrator and end-user technical personnel, students and others looking for a technical introduction to industrial robotics. The monthly one-hour webinars will cover a variety of subjects, such as Vision Guided Robotics Do's and Don'ts; Introduction to ACE; Packaging Line Layout Do's and Don'ts; Introduction to PackXpert; Robot Programming That You Already Know (ePLC); Choosing the Right Robot for the Job. More

HIV infection figures tumbling around the world
New Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Figures released by the United Nations AIDS agency show that the annual number of new HIV infections in children has more than halved since 2001, from 550,000 to 260,000. New infections overall have tumbled by a third over the same period. Death rates are falling too, from a peak of 2.3 million in 2005 to 1.6 million last year. "Many of the reductions are related to increases in the availability of antiretroviral therapy," says Peter Ghys, at UNAIDS. More


Engineers invent programming language to build synthetic DNA
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Similar to using Python or Java to write code for a computer, chemists soon could be able to use a structured set of instructions to "program" how DNA molecules interact in a test tube or cell. A team led by the University of Washington has developed a programming language for chemistry that it hopes will streamline efforts to design a network that can guide the behavior of chemical-reaction mixtures in the same way that embedded electronic controllers guide cars, robots and other devices. More

Chemistry driving hydrogen fuel-cell vehicle developments
Live Science    Share    Share on FacebookTwitterShare on LinkedinE-mail article
By Josh Goldman: In September, I had the privilege of attending the 246th American Chemical Society National Meeting and Exposition. This event provided an opportunity for chemists to collectively geek out about non-oxidative conversions, triazollium-based ionic liquids and rhodium catalysts — for example — and for chemical supply companies to showcase contraptions that jostled, stirred, shook, rotated, inverted, injected and swirled chemical compounds. More

Rocking out with carbon nanotubes
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new type of headphone heats up carbon nanotubes to crank out tunes. The tiny speaker doesn't rely on moving parts and instead produces sound through the thermoacoustic effect. The nanotube speaker could be manufactured at low cost in the same facilities used to make computer chips, the researchers say. In conventional speakers, mechanical drivers create sound waves via vibrations that compress the air in front of them. But that's not the only way to rock out. More

BMG LABTECH Introduces The CLARIOstar
BMG LABTECH is releasing its newest instrument, the CLARIOstar, a high performance microplate reader with advanced monochromators, spectrometer, and filters. With this cutting-edge, hybrid technology, the CLARIOstar offers clear superiority with unparalleled flexibility and sensitivity.

Anything is possible with BMG LABTECH’s CLARIOstar. Any wavelength. Any bandwidth. Any assay.
Low residual volume plate washing
Introducing AusWasher MTP, a plate washer with residual volume < 0.01µl, enabling the highest specificity ELISA in 96, 384,1536 well plates with dramatically reduced number of wash steps. Centrifugation eliminates aspiration of wash buffer: no clogging, uniform buffer removal, no damage from physical contact with needles. Available standalone and OEM.

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Senior Research Fellow – Principal Investigator
United States

QC Scientist – Protein Analytical Chemistry (Validation)
US – CA – South San Francisco

Assistant Research Professor Bioprocess Engineering
University of Kentucky
US – KY – Lexington

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