Official Publication of the Society for Laboratory Automation and Screening
This message contains images. If you don't see images, click here to view.
Advertise in this news brief.

Advertisement


Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit October 4, 2017

SLAS.org    SLAS2018    Moving? New job? Let SLAS know.      

Advertisement

Advertisement

Advertisement

Advertisement

Company takeover Lab Services offers opportunities

As a reliable, service oriented supplier with flexible custom made applications





 

Advertisement

news

SLAS ELN Reports: Microcontrollers, the Internet of Things and Our Laboratories
SLAS     Share    Share on FacebookTwitterShare on LinkedinE-mail article
It's been called the second industrial revolution. Whether it's shaping smarter cities, tracking our 10,000 steps a day or just making sure we never run out of laundry detergent, microcontrollers and the Internet of Things are making everyday life ... well, if not simpler, at least a bit more effortless. But how is this technology changing life in the lab? Jay Gill and Erik Werner explore this fascinating topic in the SLAS Electronic Laboratory Neighborhood e-zine feature article. In addition, these IoT enthusiasts invite you to: Gill and Werner are contributing their time and expertise as journal guest editors and short course instructors. More


Advertisement


SLAS Announces Slates for 2018 Board of Directors, Americas Council and Europe Council
SLAS     Share    Share on FacebookTwitterShare on LinkedinE-mail article
SLAS presents the following professionals for three-year terms of service beginning at SLAS2018:

SLAS Board of Directors

Emilio Diez Monedero, Pharmaceutical Industry Consultant, Madrid, Spain
Peter Brian Simpson, Chief Scientific Officer, Medicines Discovery Catapult, Alderley Park, UK
Severine Tamas-Lhoustau, Co-Founder and Managing Partner, Novoptim, Montigny le Bretonneux, France

SLAS Americas Council
Mike Berke, Director, Research & Automation Technologies, Amgen, Inc., Thousand Oaks, CA
Jonathan O'Connell, Executive Director and Head of Early Discovery, FORMA Therapeutics, Watertown, MA
Joe Olechno, Senior Research Fellow, Labcyte Inc., San Jose, CA

Europe Council
Geert Van Minnebruggen, Head of the Science Policy Unit, VIB, Ghent, Belgium
Ute Vespermann, Drug Discovery Specialist, Corning Inc., Münster, Germany

Pursuant to SLAS policy, if no valid petition nominating alternate candidates for the Board of Directors, Americas Council or Europe Council is received prior to Nov. 1, 2017, the named individuals will be moved forward to the Board for official acclamation in accordance with SLAS Bylaws.


   SPONSORED CONTENTAdvertisement

Promoted by Surmodics
 



New Approaches to Difficult Drug Targets: The Phosphatase Story
SLAS    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new review by John S. Lazo et al. of the University of Virginia in the October 2017 issue of SLAS Discovery reflects on the nature of one rather large protein class — protein tyrosine phosphatases — that has been implicated in many human diseases and explores reasons why these enzymes have been eschewed by drug hunters, and how the landscape is beginning to change. The authors place particular emphasis on how automation and innovative screens influence the search for inhibitors and activators of protein tyrosine phosphatases in the area of cancer.

Full access to this review is available to nonmembers for a limited time. Full access always is available to subscribing SLAS Premier members and all Premier Plus members.
More




Advertisement
Automate your nucleic acid analysis

Take your automated nucleic acid QC to the next level with Advanced Analytical Technologies, Inc. and Tecan Group Ltd. The Fragment Analyzer INFINITY Automated CE System seamlessly integrates with the robotic arm of the Freedom EVO line of automation solutions from Tecan, providing you with reproducible and reliable QC analysis.


SLAS Webinar Oct. 17: Detecting Small Molecule Non-Covalent Binders Utilizing SAMDI and the Bruker MALDI-TOF — Proof of Concept for a New Screening Format
SLAS     Share    Share on FacebookTwitterShare on LinkedinE-mail article
Erica C. VanderPorten, SLAS Discovery author and Genentech senior scientific researcher, presents her team's latest work to develop assays to support medicinal chemistry efforts, characterize and understand compound mechanism of action and investigate new lead finding technologies.

"Advances in technology afford the opportunity to revisit old challenges of detecting compound binding from mixtures," VanderPorten says. "We combined the ability of mass spectrometry to unambiguously identify and resolve compounds from complex mixtures of analytes with Self-Assembled Monolayers and matrix-assisted laser Desorption Ionization (SAMDI) technology."

Register for the live webinar (free to dues-paying members) on Oct. 17, and read her SLAS Discovery paper.
More


New at SLAS.org! On the Road with the SLAS CEO
SLAS     Share    Share on FacebookTwitterShare on LinkedinE-mail article
"As suggested by the SLAS Board of Directors, I began making visits to SLAS members and vendor partners to learn about your goals and objectives, as well as your challenges," says SLAS CEO Vicki Loise. "In the process, I hope to expand my knowledge of the SLAS community and how the Society might help you meet challenges and business objectives."

Read more about her first stop at Promega headquarters in Madison, WI, and check back regularly as Loise shines a spotlight on SLAS members and their unique stories and experiences.
More


Advertisement

news


Printed Meds Could Reinvent Pharmacies, Drug Research
Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A technology that can print pure, ultra-precise doses of drugs onto a wide variety of surfaces could one day enable on-site printing of custom-dosed medications at pharmacies, hospitals and other locations. The technique, developed at the University of Michigan, can print multiple medications into a single dose on a dissolvable strip, microneedle patch, or other dosing device. The researchers say it could make life easier for patients who must now take multiple medications every day. More


Nonviral CRISPR Delivery a Success
The Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
While promising, applications of CRISPR-Cas9 gene editing have so far been limited by the challenges of delivery — namely, how to get all the CRISPR parts to every cell that needs them. In a study published in Nature Biomedical Engineering, researchers have successfully repaired a mutation in the gene for dystrophin in a mouse model of Duchenne muscular dystrophy by injecting a vehicle they call CRISPR-Gold, which contains the Cas9 protein, guide RNA, and donor DNA, all wrapped around a tiny gold ball. More


Advertisement
Sponsored Content


To Speed CRISPR/Cas9's Search and Snip, Try Extra Cas9 and gRNA
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The CRISPR/Cas9 gene-editing system is advantaged by its targeting mechanism's inherent flexibility, but disadvantaged by this mechanism’s inherent slowness. The mechanism, which depends on a guide RNA (gRNA)-programmable protein, can take a long time to comb through a genome before it finally chances upon a target DNA sequence — up to six hours in a bacterial cell. The problem, say scientists based at Uppsala University, is slow kinetics. More


New Synthesis Method for Click Chemistry
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A recent study, affiliated with UNIST has presented a new way to advance the click chemistry. This is expected to be used in various areas, such as the synthetic chemistry of new drugs, development of functional high-molecules and bio-imaging. In the study, the research team has introduced a new synthetic method to obtain a novel triazole structure, used for the production of drugs and high molecules. More




Advertisement
KMC Systems Engineering & Manufacturing

KMC Systems is a leading provider of engineering services and contract manufacturing for the development, design and production of medical and life sciences instrumentation. We specialize in developing mechanized processes for tightly controlled and highly automated systems and manufacturing complex, highly-regulated instruments for the clinical environment.


Writing on Nanocrystals: Patterning Colloidal Inorganic Nanocrystal Films through Irradiation-Induced Chemical Transformations of Surface Ligands
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In the past couple of decades, colloidal inorganic nanocrystals (NCs) and, more specifically, semiconductor quantum dots (QDs) have emerged as crucial materials for the development of nanoscience and nanotechnology, with applications in very diverse areas such as optoelectronics and biotechnology. Films made of inorganic NCs deposited on a substrate can be patterned by e-beam lithography, altering the structure of their capping ligands and thus allowing exposed areas to remain on the substrate while non-exposed areas are redispersed in a solvent. More


Reinvestigation of Periodate Chemistry Challenges Conventional View
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Periodate — an ion composed of iodine, oxygen, and hydrogen — was studied in water-based solutions extensively from the 1950s to the 1980s. Ever since those studies, chemists have accepted that periodate exists in solution as orthoperiodate (H5IO6) and metaperiodate (IO4) species in equilibrium with each other, along with a dimer (H2I2O104–). More


   PRODUCT SHOWCASEAdvertisement
Seamless Inventory Integration Across BMS

Jeff Chin, Research Scientist at Bristol-Myers Squibb, shares his experience using Titian Software's Mosaic Sample Management across their local and international sites. Discover how BMS benefited from Mosaic software to seamlessly integrate their inventory.


Researchers Explore Ways That a Drug Like Avandia Can Be Made Safer
Phys.org    Share    Share on FacebookTwitterShare on LinkedinE-mail article
With the heightened concerns over the dangerous side effects of the once-popular antidiabetic drug Avandia, researchers at The Scripps Research Institute (TSRI) in Jupiter, Florida, are working to understand how small molecules, like those in Avandia, can have such varied effects throughout the body. The insights could help researchers design new drugs with better efficacy and fewer side effects. More




Antibody Protects Against Both Zika and Dengue, Mouse Study Shows
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Brazil and other areas hardest hit by the Zika virus — which can cause babies to be born with abnormally small heads — are also home to dengue virus, which is spread by the same mosquito species. A new study led by researchers at Washington University School of Medicine in St. Louis shows that an antibody that protects against dengue virus is also effective against Zika in mice. More


Career


Molecular Imaging Program Faculty Position
Stanford University
US – CA – Stanford

Director Molecular Genetics and either Cytogenetics or Biochemical Genetics
EGL Genetic Diagnostics, LLC
US – GA – Tucker

Faculty Position in Plant Biotechnology
Massachusetts Institute of Technology
US – MA – Cambridge

Search Jobs at SLAS Career Connections


news

 


SLAS Point-to-Point
Colby Horton, Vice President of Publishing, 469.420.2601
Download media kit

Dennis Hall, Executive Editor, 469.420.2656   
Contribute news

This edition of SLAS Point-to-Point was sent to ##Email##. To unsubscribe from receiving SLAS Point-to-Point, click here. To unsubscribe from all SLAS e-mail communications, please click here. Did someone forward this edition to you? Subscribe here — it's free!

SLAS Terms of Use Policy

MultiView Privacy Policy 

Recent issues

Sept. 27, 2017
Sept. 20, 2017
Sept. 13, 2017
Sept. 6, 2017






7701 Las Colinas Ridge, Ste. 800, Irving, TX 75063