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  Mobile version   RSS   Subscribe   Unsubscribe    SLAS2012   Moving? New job? Let SLAS know.    Oct. 5, 2011



SLAS speaker awarded National Medal of Science
The White House    Share    Share on FacebookTwitterShare on LinkedinE-mail article
While participating in the recent SLAS stem cell global symposium, Dr. Rudolph Jaenisch, Whitehead Institute for Biomedical Research and the Massachusetts Institute of Technology, was being named recipient of this top award. More


Critical technologies for ion channel drug discovery
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Ronald J. Knox, Bristol-Myers Squibb Research, discusses the large technology landscape that has grown around the core patch-clamp technique over the last three decades in this SLAS virtual course. Live Oct. 6 or On-Demand. More

Add-and-Read Plate Reader
Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.

A friend's tribute to Jim Little
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"Colleagues, customers, family and friends all were enriched through their relationship with Jim Little." Read more from Frank Zenie about his friend and colleague, Jim Little, who passed away Sept. 14. More


Lee article generating interest
Journal of Biomolecular Screening    Share    Share on FacebookTwitterShare on LinkedinE-mail article
"Open Innovation for Phenotypic Drug Discovery: The PD2 Assay Panel" by Jonathan Lee, et al., July 2011 (16.6) JBS. This is a novel topic and getting a lot of buzz in blogs and social media. More

SLAS2012 exhibition tops 500 booths
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Laboratory science and technology companies from around the world have made their plans to show you the latest innovations at the First Annual SLAS Conference and Exhibition, Feb. 4-8, San Diego. Explore the offerings. More

Miniaturize Genotyping

The Echo® liquid handler enables low volume genotyping reactions in a 384-well format with as little as 500 nL total reaction volume.

Virtual course speaker Lipinski on drug discovery trends
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Chris Lipinski shares industry observations in this video filmed from March 2011. He offers thoughts on fostering creativity — "you absolutely need to have time to think." Lipinski is one of four speakers for Oct./Nov. chemical space course. More

SLAS Point-to-Point available through MultiBriefs mobile app
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SLAS Point-to-Point, distributed weekly, is available on MultiBriefs app for Apple iPhone/iPod Touch, Android or Blackberry users. Start at the MultiBriefs homepage and select your smartphone format. Once downloaded, simply add the SLAS feed. More
Introducing the BIND® SCANNER from SRU Biosystems
SRU Biosystems has introduced the first and only high resolution, optical, label-free plate reader. Capable of measuring functional responses in individual cells, the SCANNER represents a new paradigm in drug discovery enabling the use of primary cells earlier in drug discovery process. Contact us to learn more.
Ultra Low Attachment Surface in HTS
Ultra Low Attachment Surface plates feature a covalently bound hydrogel layer that effectively inhibits cellular attachment, minimizes protein absorption, enzyme activation, and cellular activation. Corning® introduces 384 well black clear bottom Ultra Low Attachment Surface plates for HTS applications of tumor spheroid and stem cell embryoid body screening.
Douglas Scientific's Soellex™ PCR Thermocycler
The Soellex™ PCR thermocycler is optimized for Array Tape™ to provide ultra high capacity DNA amplification – simultaneously processing up to 230,000 reaction wells in a standard run. The heating system in the Soellex™ tightly controls the temperature throughout the water column delivering efficient and rapid energy transfer. MORE


Electroanalytical eavesdropping on single cell communication
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The use of carbon as an electrode material was first popularized by Ralph Adams in the 1950s. Since its inception, carbon has been a popular choice for electrochemical applications, as carbon electrodes demonstrate a wide working potential window, stable background currents, low noise and high sensitivity. More


Self-organizing surface-initiated polymerization: Facile access to complex functional systems
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Facile access to complex systems is crucial to generate the functional materials of the future. Herein, we report self-organizing surface-initiated polymerization as a user-friendly method to create ordered as well as oriented functional systems on transparent oxide surfaces. More

The telomeric Cdc13 protein interacts directly with the telomerase subunit Est1 to bring it to telomeric DNA ends in vitro
National Academy of Sciences    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In Saccharomyces cerevisiae, a Cdc13–Est1 interaction is proposed to mediate recruitment of telomerase to DNA ends. Here we provide unique in vitro evidence for this model by demonstrating a direct interaction between purified Cdc13 and Est1. The Cdc13–Est1 interaction is specific and requires the in vivo defined Cdc13 recruitment domain. More


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Physicists say speed-of-light-breaking neutrinos would've lost energy along way
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Last week's bombshell physics news — those superluminal neutrinos that CERN's OPERA experiment clocked moving faster than the speed of light — are already getting the rigorous vetting that OPERA's researchers were hoping for. And some physicists are already rejecting the notion that CERN's neutrinos broke the cosmic speed limit outright. More

Bridging the gap
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Contract research organizations have a natural tendency to bridge gaps in the landscape of pharmaceutical R&D. As laboratories for hire, CROs have emerged as vital agents in screening compounds, developing synthetic routes and supporting clinical trials. They provide expertise and infrastructure to virtual drug companies, small biotech firms and even big pharmaceutical makers that lack necessary resources. More


Polymeric material has potential for noninvasive procedures
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Scientists at the University of California, San Diego, have developed what they believe to be the first polymeric material that is sensitive to biologically benign levels of near infrared irradiation, enabling the material to disassemble in a highly controlled fashion. The study represents a significant milestone in the area of light-sensitive material for non-invasive medical and biological applications. More

Diabetes and cancer: A shared biological basis
eBio News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Contrary to what some think, cancer and diabetes appear to have some biology in common. According to a report in the Sept. 30 issue of the Cell Press journal, Cell, a pathway that initially drew attention for its role in embryonic stem cells and cancer also influences the odds that mice develop or resist diabetes. More

Single magnesium ion brought to standstill by simple laser cooling
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Quantum logic is quite a new and absolutely fascinating field of physics and might — ultimately — lead to the fabrication of a quantum computer. And it could also aid the search for the "theory of everything" — the missing link between traditional physics and quantum physics. More

2011 AAPS Annual Meeting and Exposition
Oct. 23-27, Washington, D.C.

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"The Next 25 Years" is the theme for the AAPS meeting this 25th anniversary year, with sessions on bioequivalence, biopharmaceutics classification system, combination products, modified release, nanotechnology, quality by design and systems analysis. More

Tired of Hand-Labeling
Your Tubes?

The Sci-Print VX2 automates the mundane task of hand-labeling tubes and vials. User-friendly software interfaces with LIMS or worklists to generate label information. The system can label microtubes, vials and vacutainers ranging from 0.5mL up to 50mL. The Sci-Print VX2 prints human readable text as well as 1D/2D barcodes.
Automated Benchtop Cell Analysis Platform
The HTFC® Screening System from IntelliCyt is a fast, highly sensitive, and simple-to-operate multicolor platform for phenotypic screening. This automation-friendly system can analyze thousands of cells per second from 96 or 384 well microplates and create heatmap data displays to quickly visualize hits.
Sample Screening from your Compound
The comPOUND system comprises a high-density sample storage unit and an additional suite of specialized delivery and processing modules to enable easy integration into any compound management or screening system.


M+Visión Fellowship in Translational Biomedical Imaging
Madrid-MIT M+Visión Consortium
Spain and USA – Madrid and Cambridge, MA

Principal Research Scientist II
BASF, The Chemical Company
USA – NC – Research Triangle Park

Principal Scientist, ADHTS
Boehringer Ingelheim
USA – CT – Ridgefield

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BioMicroLab Sample Management Automation Systems

Affordable Benchtop Instruments:
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The Nexus Generation of Life Science Solutions

Nexus Biosystems- your partner in Discovery Science processes from Sample Storage to Sample Analysis Solutions.


Discovery is our mission...

Venenum BioDesign specializes in HTS of 5.5 million compounds including new libraries for protein-protein interactions.

Totally automated. Highly interactive.

Boost your career or find the perfect candidate. SLAS Career Connections offers both online and in-person career services.

Expert Advice/Stimulating Conversation

Discussions and musings focused on the engaging field of laboratory science and technology.

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