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Keep the Bad Bugs Out
This week on New Matter: Inside the Minds of SLAS Scientists, host Mike Tarselli and guest Lynn Rasmussen (Southern Research) discuss COVID, social distancing, the revelation of lab automation and what it’s like to wear a “personal fume hood” to do her lab work. (They also get into her organization’s seven FDA-approved molecules as well.)
LISTEN NOW
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.SLAS NEWS
Innovation AveNEW Application Deadline is This Monday
SLAS
This Monday, October 12, is the last day to submit applications for the SLAS2021 Digital Innovation AveNEW and compete for the $5,000 Ignite Award. As a reminder, chosen Innovation AveNEW start-up and emerging technology exhibitors will have the opportunity to amplify their company’s brand and connect with purchasing influencers and decision-makers from around the world — without paying ANY exhibition fees. The competition is heating up – finalize your application and submit now!
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SLAS2021 Digital Registration Now Open!
SLAS
Registration for SLAS2021 Digital (January 25-27, 2021) is open. January’s online conference and exhibition will be a globally accessible adaptation of the in-person event. Access to the sessions will be live and on-demand, allowing for the ultimate flexibility. (Pretty convenient if you ask us.) SLAS2021 will feature a global-friendly programming schedule with more than 80 scientific sessions, three keynote addresses, short course workshops (scheduled on January 28), new product announcements, awards, networking opportunities (and more!) across three-days. Join the dedicated scientific and technology community for the latest research in drug discovery and lab automation, from your lab, office, kitchen table or favorite hiding place.
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The Thermo Scientific™ Orbitor™ RS2 microplate mover is a collaborative bench-top mover that provides unbeatable reliability and improved process efficiency. It’s innovative bi-directional telescoping arm coupled with it’s expansive 360° workspace provide exceptional reach and precision, making the Orbitor RS2 your trusted laboratory productivity partner.
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Filling Fast! Q&A on Biotech Start-Ups Member Meet-Up is Tomorrow
SLAS
The latest SLAS Member Meet-Up is Thursday, October 8, from 12:00 - 1:00 p.m. CDT. Grab your seat for an interactive Q&A on biotech start-ups hosted by Colin Cox, Ph.D., (Seer), Coleman Murray, Ph.D., (Ferrologix) and Tony Jones, Ph.D., (OneNucleus). Attendees can expect a fireside chat atmosphere with plenty of time for questions from the participants.
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Finding a Mentor is Easy with SLAS Mentor Match
SLAS
The SLAS Mentor Match program, a featured benefit of SLAS membership, helps students and early career scientists and technology professionals pair up with an experienced related-industry professional. Available within SLAS CONNECTED, Mentor Match is a streamlined way to link up with someone within the same area of interest who can help broaden career development through interviewing and résumé tips, skill-building and sharing valuable advice. Remember, students and early career professionals can enroll in SLAS at a reduced price; $45 and $70 respectively.
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Introducing the BioXp™ 3250 system, a fully automated synthetic biology workstation. It dramatically reduces the timelines for identifying antibody and vaccine candidates from weeks to days by assembling DNA clones, libraries, and gene fragments — as long as 7,000 base pairs — in a single overnight run.
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.HEADLINES
Improving Fatigue Resistance of Dihydropyrene by Encapsulation within a Coordination Cage
Journal of the American Chemical Society
Photochromic molecules undergo reversible isomerization upon irradiation with light at different wavelengths, a process that can alter their physical and chemical properties. For instance, dihydropyrene is a deep-colored compound that isomerizes to light-brown cyclophanediene upon irradiation with visible light. CPD can then isomerize back to DHP upon irradiation with UV light or thermally in the dark.
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Concentrating and Releasing Drugs in the Brain with Pinpoint Accuracy
Genetic Engineering & Biotechnology News
Scientists at ETH Zurich say they have developed a technique for concentrating and releasing drugs in the brain with much accuracy. This could make it possible in the future to deliver psychiatric and cancer drugs and other medications only to those regions of the brain where this is medically desirable, according to the team.
Today, the researchers add, this is practically impossible — drugs traveling through the bloodstream reach the entire brain and body, which in some cases causes side effects.
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Deep Learning Gives Drug Design a Boost
Science Daily
When you take a medication, you want to know precisely what it does. Pharmaceutical companies go through extensive testing to ensure that you do.
With a new deep learning-based technique created at Rice University's Brown School of Engineering, they may soon get a better handle on how drugs in development will perform in the human body.
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Aurora is 100% focused on making the highest quality, highest performing Microplates available. We use the best materials, the cleanest and most precise molding operations for our Microplates. We believe that the best Microplates should be an invisible carrier for your work - not a contributor to variability in your data.
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Medicine Nobel Honors 3 Scientists for Discoveries on Hepatitis C Virus
Science Magazine
The Nobel Committee has awarded this year’s Nobel Prize in Physiology or Medicine for the discovery of the hepatitis C virus, one of the most common causes of liver cancer. The prize was given to Harvey Alter of the U.S. National Institutes of Health; Michael Houghton of the University of Alberta, Edmonton; and Charles Rice of Rockefeller University.
The hepatitis C virus is transmitted via blood.
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Alder-Ene-Catalyzing Enzymes Discovered
Chemical & Engineering News
Pericyclic reactions, which involve concerted electron movement and a cyclic transition state, have long been a part of the synthetic chemist’s tool box. But finding enzymes that catalyze such reactions, particularly a class called Alder-ene reactions, has been difficult. A research team has now found Alder-ene enzymes that might be used as biocatalysts to more efficiently make compounds that contain substituted pentenes.
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Promoted by Iscaffpharma
Sortina Pharma use Iscaffpharma’s patient derived scaffolds to create drug fingerprints and select drugs for aggressive cancer. Read Case
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Method Helps Uncover Patterns in SARS-CoV-2's Genetic Mutations
Lab Manager
Drexel University researchers have reported a method to quickly identify and label mutated versions of the virus that causes COVID-19. Their analysis, using information from a global database of genetic information gleaned from coronavirus testing, suggests that there are at least eight to 14 slightly different versions of the virus infecting people in America, some of which are either the same as, or have subsequently evolved from, strains directly from Asia, while others are the same as those found in Europe.
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New Techniques Probe Vital and Elusive Proteins
Phys.org
The number of proteins in the human body, collectively known as the proteome, is vast. Somewhere between 80,000 and 400,000 proteins circulate in our cells, tissues and organs, carrying out a broad range of duties essential for life. When proteins go awry, they are responsible for a myriad of serious diseases.
Now, researchers investigate a critically important class of proteins, which adorn the outer membranes of cells.
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Matrigel matrix-3D plates are a pre-coated, convenient, off the shelf option that improve productivity and consistency in homogenous assays where 3D structures are grown and assayed directly in the plate. Using a pre-coated option eliminates the need to handle small volume ECM dispensation and helps reduce workflow steps
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The Cooperative Human Tissue Network (CHTN) is a unique NCI supported resource that provides human tissues and fluids prospectively from surgeries, autopsies and other routine procedures to investigators who utilize human biospecimens in their research. Visit our website for more information and pricing or contact our Central Coordinator.
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.CAREER CONNECTIONS
Job Seekers: Post your résumé and sign up for new job alerts by keyword.
Employers: Search résumés, post an open position, internship or post-doc opportunity. SLAS Premier and Corporate Members get a discount on all new job postings.
Postdoctoral Fellow, Abudayyeh-Gootenberg Lab
Massachusetts Institute of Technology (MIT)
US – MA – Cambridge
Postdoctoral Fellow - Chemical and Biological Engineering
Iowa State University
US – IA – Ames
Medical Technologist (Technical Specialist-Flow Cytometry)
Veterans Affairs, Veterans Health Administration
US – LA – New Orleans
Search Jobs at SLAS Career Connections
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Fluorescent 3CLpro/Mpro Inhibitor AssaySARS-CoV-2 Pseudovirus Fluorescent ReporterFluorescent BacMam Host Factors
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.THANK YOU 2020 SLAS CORPORATE MEMBERS
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 7701 Las Colinas Ridge, Ste. 800, Irving, TX 75063
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