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Certified UPS’s to protect your laboratory’s critical instrumentation and resolve current and potential power issues.
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Discussions and musings focused on the engaging field of laboratory science and technology.
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Boost your career or find the perfect candidate. SLAS Career Connections offers both online and in-person career services.
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SLAS2013 Innovation AveNEW deadline is Oct. 15
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Are you a new company with an innovative product or service for the laboratory science and technology audience? SLAS2013 Innovation AveNEW is your opportunity to get in front of 4,500 seekers of new tools for improved work. Entrepreneurial companies selected for this designated area of the SLAS2013 exhibit floor receive exhibit space, travel/housing for one company representative and the opportunity to participate in Late Night with LRIG: Rapid-Fire Innovation Session. Apply by Oct. 15.
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ANSI accredits SLAS Microplate Standard 6
SLAS Share
SLAS President Dave Dorsett announced that the American National Standards Institute has accredited SLAS Microplate Standard 6 for Well Bottom Elevation. This new standard (ANSI/SLAS 6-2012) provides the scientific community with more sound direction for the automated processing of microplates. It defines standardized terminology and measurement protocols for well bottom elevation and well bottom elevation variation, and outlines the conditions required for making necessary measurements. Dorsett offers kudos to the SLAS Microplate Standards Special Interest Group and the SLAS professional team who worked diligently through the accreditation process.
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SLAS2013 Event Scheduler provides deep look at scientific sessions
SLAS Share
Use the handy SLAS2013 Event Scheduler to review podium presentation abstracts, explore special events and see what your days might look like at SLAS2013, Jan. 12-16, Orlando, Fla. With meaningful filters and robust search, you can zero in on topics of interest for further review. It's mobile friendly, too!
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ALPAQUA® offers 24-well, 96-well & 384-well magnet plates with integrated spring technology for touch-off dispensing and complete supernatant removal while eliminating costly tip crashes and occlusions. Strong NdFeB magnets enable rapid, reliable bead capture and retention. Alpaqua magnet plates are SBS compliant and compatible with many liquid handlers, plate hotels & stackers.
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New LabAutopedia book
SLAS Share
Free Radicals: The Secret Anarchy of Science is the Book of the Month on LabAutopedia. Author Michael Brooks takes a deep look at the "secret side of science" and his findings reveal information often untold when reporting scientific breakthroughs.
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JALA Online features new manuscripts ahead-of-print
SLAS Share
"Mathematical Modeling of Vesicle Drug Delivery Systems 1: Vesicle Formation and Stability Along with Drug Loading and Release" and "Clarity: An Open-Source Manager for Laboratory Automation" are among the new manuscripts available only to SLAS Laboratory Automation Section members ahead of print.
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The Nexar® system provides inline sample storage, liquid handling, incubation, and detection. High throughput, miniaturized reaction volumes and walk-away operation. Check it out!
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In human and ortholog GPCR stable cell lines in Calcium, cAMP, IP-1, GTPγS, ligand-binding and internalization assays, offering the fastest turnaround, highest quality and most diversity. More>>
Email: info@multispaninc.com
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SLAS Members: Oct. 31 deadline for maximum savings
SLAS Share
The members-only SLAS2013 early registration discount is available until the end of the month. Claim another benefit of Society membership and register by Oct. 31 to join 4,500 of the laboratory science and technology community's most innovative thought leaders for five days of inspiration and education.
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Medicine Nobel awarded to stem cell pioneers who reprogrammed adult cells
Popular Science Share
Congratulations to John B. Gurdon and Shinya Yamanaka, winners of this year's Nobel Prize in physiology/medicine for their work on adult stem cells. The two conducted groundbreaking work discovering that mature cells can be reprogrammed to become immature cells, capable of becoming any cell in the body — upending our understanding of how cells work, and providing a less-controversial avenue for research on stem cells.
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Testing drug stability for long-term storage
Drug Discovery & Development Share
Although drug discovery gets much of the attention in the pharmaceutical industry, stability plays an equally fundamental role. A drug must remain potent and safe long after it leaves a manufacturing facility. Ensuring this safety requires a range of technologies and applications.
The complexity of stability testing arises from the many factors that must be considered.
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Invisible RNAs as anti-HIV drug targets
Genetic Engineering & Biotechnology News Share
Scientists say they have visualized, for the first time, fleeting changes in RNA structure that direct biological function through altered cell signaling, and may represent a completely new class of targets for the development of drugs, including those against viral and bacterial pathogens.
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SRU Biosystems has introduced the first and only high resolution, optical, label-free plate reader. Capable of measuring functional responses in individual cells, the SCANNER represents a new paradigm in drug discovery enabling the use of primary cells earlier in drug discovery process. Contact us to learn more.
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Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.
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At Molecular Devices, we understand your desire for a top-of-the-line multi-mode microplate reader while balancing an ever-tightening budget. Get the reliability and sensitivity your lab deserves at the price-point you need from a name you trust. Learn more at info.moleculardevices.com
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Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
Nature Chemical Biology Share
Mechanisms by which autophagy promotes cell survival or death are unclear. We provide evidence that C18-pyridinium ceramide treatment or endogenous C18-ceramide generation by ceramide synthase 1 (CerS1) expression mediates autophagic cell death, independent of apoptosis in human cancer cells.
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Mouse eggs created from stem cells for the first time
New Scientist Share
Mouse eggs can now be cooked up from scratch. Using stem cells, a Japanese team has created healthy eggs that, once fertilized, grow into normal mouse pups. Both egg and sperm cells start life as primordial germ cells. Last year, Katsuhiko Hayashi and his colleagues found they could generate PGC-like cells from either mouse embryonic stem cells or body cells that can turn into stem cells — known as induced pluripotent stem cells or iPSCs.
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Formation of an unusual four-membered nitrogen ring (tetrazetidine) radical cation
Journal of the American Chemical Society Share
Treatment of triphenylphosphine (Ph3P) with an excess of diisopropyl azodicarboxylate at 0–25°C resulted in the formation of a symmetrical tetraalkyl tetrazetidinetetracarboxylate radical cation, containing the elusive cyclic N4 ring system. Electron paramagnetic resonance spectroscopy revealed a 9-line spectrum, with hyperfine coupling constants indicative of four almost magnetically equivalent nitrogen atoms.
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BUSM study investigates genetic variants' role in increasing Parkinson's disease risk
eBioNews Share
Boston University School of Medicine investigators have led the first genome-wide evaluation of genetic variants associated with Parkinson's disease. The study, which is published online in PLOS ONE, points to the involvement of specific genes and alterations in their expression as influencing the risk for developing PD.
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Starfruit Software/ Database Service - Your clients test requisitions online. You save clerical typing time and the notorious typing error. Visit Store to see "Starfruit LIMS"
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The EXCM is a new Cartesian robot employing parallel kinematics to make flat, ultra compact sample handling systems; the latest in a wide variety of innovative handling products by Festo. MORE
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Selective tumor treatment: β-galactosidase releases active agent from prodrugs
Phys.org Share
One of the largest challenges of chemotherapy lies in the fact that cancer cells must be killed while healthy tissue must be protected. French researchers have now introduced a new approach in the journal Angewandte Chemie: The enzyme β-galactosidase releases the active drug from an inactive precursor, known as a prodrug, which can only be taken up by tumor cells.
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New etching method to produce 3-D microstructures in silicon for processing of light signals in telecommunications
Science Daily Share
In modern telecommunications, light carries digital information over kilometers within seconds. Adapted optical materials control the light signals. In the journal Advanced Functional Materials, researchers present a method to produce photonic crystals. Their optical properties are adjusted by structures of micrometer size. The method is rapid, cheap, and simple and partly uses the self-organization principle.
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Painkiller found in snake venom
Chemical & Engineering News Share
French researchers have discovered potent painkilling peptides from an unlikely source — the venom of black mamba snakes. The peptides, which relieve pain in mice as powerfully as morphine does, act by a mechanism different from that of available painkillers. The discovery could help researchers expand the legions of painkillers, which currently rely heavily on opioids that carry side effects and potential for abuse.
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Gut bacteria build weapons from viruses
Live Science Share
Bacteria in the gut can unexpectedly manufacture viruses to kill off rivals during intestinal shootouts of sorts, researchers have found. These findings could help lead to new ways to kill off dangerous germs, scientists added. The average human gut is home to trillions of bacteria that outnumber human cells in the body by a factor of 10 to 1. Often these bacteria are helpful, aiding in digestion and synthesis of key vitamins.
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INTEGRA’s disposable reagent reservoir system combines low-cost, crystal clear polystyrene reservoirs with clearly marked, graduated and reusable bases. The reagent reservoir inserts have been designed to be stackable, making it possible for the reservoirs to be stored in half the space compared to alternative designs.
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Are you interested in outsourcing your cell/ biochemical assay development, compound screening or equipment validation to experienced pharma scientists?
We are a pre-clinical CRO specialising in bespoke bioassay development, plate-based compound pharmacology and instrument/reagent validation.
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Contact us at enquiry@aureliabio.com
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Datapilot, along with its database, complements our existing product offerings for the laboratory automation market. Datapilot is a web-enabled LIMS component which allows user administration, data-tracking and remote control of an automated system through a web browser.
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