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SLAS.org    SLAS2012   Moving? New job? Let SLAS know.    Oct. 12, 2011



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SLAS journal showcases technological breakthroughs
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The October issue of JALA features the JALA Ten — those leading discoveries that are helping to shape the next generation of transformative technologies for biology and medicine. More

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Interrogating Chemical Space virtual course begins Oct. 25
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Chris Lipinski, Dan Erlanson, Mike Hann and Dan Wyss explore lead discovery from multiple angles during "Interrogating Chemical Space — Rules, Filters, Fragment-Based Screening and Beyond." Experience this four-module course live or on-demand. And, be sure to read the ELN feature on this topic. More

JALA Editorial Board member en route to White House
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Congratulations to Ali Khademhosseini, Ph.D., of Harvard Medical School in Cambridge, Mass., who will be meeting with President Obama to receive a 2011 Presidential Early Career Award for Scientists and Engineers. More



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JBS goes mobile
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Be sure to visit JBS on your smartphone to experience the new mobile-optimized format featuring full-text content of the current issue, archives and OnlineFirst articles, as well as simplified search, authentication and sharing tools. More

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Keys to success via laboratory technology
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"The path from scientific hypothesis to final conclusion is, regardless of technology, still rooted in asking and answering good scientific questions." Read more from SLAS Director of Education Steve Hamilton on pages 57-59 of the Autumn issue of Innovation Into Success, a publication of the United Kingdom Science Park Association. More

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SLAS2012 registration discounts through Oct. 31
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SLAS members registering by Oct. 31 save up to $300 to attend the First Annual SLAS Conference and Exhibition, Feb. 4-8, San Diego. More
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Electrochemical nanosensor for real-time direct imaging of nitric oxide in living brain
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As gaseous nitric oxide, a critical and multifaceted biomarker, diffuses easily once released, identifying the precise sources of NO release is a challenge. This study developed a new technique for real-time in vivo direct NO imaging by coupling an amperometric NO nanosensor with scanning electrochemical microscopy. More

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Total synthesis of (—)-N-methylwelwitindolinone C isothiocyanate
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
We report the first total synthesis of (−)-N-methylwelwitindolinone C isothiocyanate. Our route features a number of key transformations, including an indolyne cyclization to assemble the [4.3.1]-bicyclic scaffold, as well as a late-stage intramolecular nitrene insertion to functionalize the C11 bridgehead carbon en route to the natural product. More

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Hepatocyte entry leads to degradation of autoreactive CD8 T cells
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Although most self-reactive T cells are eliminated in the thymus, mechanisms to inactivate or control T cells specific for extrathymic antigens are required and exist in the periphery. By investigating the site in which autoreactive T cells are tolerized, we identify a unique mechanism of peripheral deletion in which naïve autoreactive CD8 T cells are rapidly eliminated in the liver after intrahepatic activation. More

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Mass spectrometry propels the field of lipidomics
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In the "omics" world, lipids have long been in the shadows, while nucleic acids and proteins hogged the limelight. But now, this broad-ranging class of biomolecules is stepping into the spotlight as well. And mass spectrometry is the tool that is making it possible. More

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Perspective article examines conductivity at the LaAlO3 and SrTiO3 (001) interface
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Complex oxides have the potential to inject new functionalities into technologies that require semiconductors. The correlated behavior of itinerant electrons in these materials sets complex oxides apart from traditional semiconductors such as Si and GaAs. Potential applications abound, but the fundamental properties of these materials, particularly when combined to make interfaces, must be understood. More

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Ancient gene found to control potent antibody response to retroviruses
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A researcher at MIT's Koch Institute for Integrative Cancer research has identified a gene that controls the process by which antibodies gain their ability to combat retroviruses. Edward Browne shows that the gene TLR7 allows the antibody generating B cells to detect the presence of a retrovirus and promotes a process by which antibodies gain strength and potency, called a germinal center reaction. More



Bacteria in your belly button
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Unknown and mysterious species of microbe lurk in our belly buttons, the Bellybutton Biodiversity project, is finding. Preliminary results from the project, based at North Carolina State University, show hundreds of new or little-known types of bacteria living in navels. Some of these miniscule creatures can grow into fuzzy colonies on Petri dishes. More

Searching for life in all the right places
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Curious about just how astrobiologists plan to make good on their goal to find life in space in the next 20 years? Popular Science has compiled some of the coolest upcoming search-for-life projects they could find — check out a feature on the subject, and browse a photo gallery for a guide to some of the most impressive efforts directed at finding extraterrestrial life. More


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Career

Associate Director/Director of Commercial Planning & Operations – HIV Franchise Strategy
Gilead Sciences
USA – CA – Foster City

Clinical Lab Scientist
Pomona Valley Hospital
USA – CA – Pomona

Research Engineer – Combustion
PPG Industries, Inc.
USA – PA – Pittsburgh

More jobs at SLAS Career Connections


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Scientific Education at Your Convenience

The all-new, four-part SLAS virtual course – Interrogating Chemical Space – kicks off Oct. 25. Register today!



JALA: Leading Peer-Reviewed Journal

JALA is a multi-disciplinary international forum devoted to the advancement of technology in the laboratory.


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