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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit October 14, 2015

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SLAS Webinar Oct. 21: Current Applications for Mass Spectrometry within Drug Discovery
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2015 SLAS Innovation Award winner Jonathan Wingfield of AstraZeneca reviews current state-of-the-art mass spectrometry technologies designed to support drug screening applications as well as some of the exciting cutting-edge developments that could enable mass spectrometry to have a greater impact within drug discovery.

The Oct. 21 SLAS Webinar, presented by JALA and JBS, the official journals of SLAS, is free to SLAS dues-paying members. Wingfield is guest editor (with Ian Wilson) of the to-be-published JBS Special Issue on Advances in Mass Spectrometry within Drug Discovery. Read more about Wingfield and his work in a recent SLAS Electronic Laboratory Neighborhood e-zine article.
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SLAS2016 Podium Presentation Lineup Unveiled
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Access the SLAS2016 Event Scheduler to see the just-published lineup of 136 podium presentation titles, abstracts and presenters. With the SLAS2016 Event Scheduler, you also can plan and save your personal itinerary and share your favorite aspects of the conference via social media. The SLAS2016 Event Scheduler links directly to the SLAS2016 Conference App (coming in January) seamlessly, so begin planning your SLAS2016 itinerary now!

Deeply discounted SLAS2016 early bird registration rates, exclusively for SLAS members, are available through Oct. 30. Join or renew your SLAS membership today to take advantage of these special rates, plus enjoy year-round member benefits through the end of 2016. Organizations that send five or more employees can save even more by taking advantage of group registration discounts.
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SLAS ELN Reports: Steve Rees — Learning and Collaboration are Key to Great Science
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"Don't try to solve problems by yourself," advises SLAS Europe Council member Steve Rees of AstraZeneca in the latest feature article published in the SLAS Electronic Laboratory Neighborhood e-zine. "Many of us early in our careers consider asking for help as a mark of failure, but that's wrong," he says. "Seek out those who have information you need. It is absolutely common sense to identify who can help you and reach out to them."

Rees adds he has found the SLAS community to be one of the best places to find key collaborators.
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Win a $500 Amazon Gift Card: Enter the JALA & JBS Art of Science Contest
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Visualization plays an important role in the presentation of scientific work, and often scientific images create mesmerizing shapes, patterns and designs that capture attention and imagination. These are the images JALA and JBS seek for the 2016 Art of Science Contest.

Ten finalists will receive 60 days free online access to the SAGE Pharmacology and Biomedical Collection, and one grand prize winner will receive a $500 Amazon gift card. Entries are due Jan. 4, 2016. See last year’s winners.
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Build Community at the SLAS2016 Corner Bars
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SLAS knows that when the SLAS2016 program day is done, participants want to continue conversations with new friends and future collaborators. To facilitate connections, SLAS has secured exclusive SLAS-only discounts at three nearby establishments: Grab a colleague, wear your SLAS2016 badge and take advantage of these opportunities. More


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JALA Podcast: Special Issue on In Vitro Diagnostic Technology Reviews from Keck Graduate Institute School of Applied Life Science
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Keck Graduate Institute Professors Angelika Niemz, Ph.D., and Jim Osborne, Ph.D., talk about the issue's topics of infectious diseases, oncology, neurodegenerative disorders and prenatal diagnostics. Niemz and Osborne knew it would take a lot of effort to push the students through the additional hurdles of peer-reviewed publishing after the formal class time ended.

"When we proposed the idea to the students, they were very enthusiastic despite the extra work they would need to invest to get their manuscripts published," Niemz says.
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SLAS Europe: VII Spanish Drug Discovery Network Meeting
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SLAS is proud to collaborate with the Spanish Drug Discovery Network and feature the latest achievements in chemical biology, drug discovery and translational research at the Nov. 12-13 meeting at the Parc Cientific de Barcelona in Barcelona, Spain. Four sessions are planned:
  • Innovation in Assay Development and Screening: New Cellular Models and New Technologies
  • Target Identification and Validation: Phenotypic Screening and Target Engagement
  • Chemical Biology and Systems Biology in Drug Discovery and Development: Data Integration
  • Public-Private Partnerships and Open Innovation in Action: Enabling (or Accelerating) Drug Discovery
Register today.
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Nobel Prize in Chemistry Awarded to DNA Repair Researchers
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Recipients of the Nobel Prize in Chemistry were announced, acknowledging three scientists who made fundamental contributions to the study of how cells repair DNA and maintain genomic integrity. Each day our DNA is damaged by UV radiation, free radicals, and other carcinogenic substances. However, even without such external attacks, a DNA molecule within the cell is inherently unstable. Thousands of spontaneous changes to a cell's genome occur on a daily basis and defects can arise when DNA is copied during cell division, a process that occurs several million times every day in the human body. More


Gene-Editing Method Revives Hopes for Transplanting Pig Organs Into People
Science Magazine    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Thanks to a powerful new gene-editing technique, researchers have made a stride toward engineering safer pig organs for human transplants. In a paper in Science, they describe using the CRISPR editing method in pig cells to destroy potentially harmful DNA sequences at 62 sites in the animal's genome. It's the most extreme example to date of the precise yet widespread genetic changes possible through CRISPR. More




Quantum Dots: Electrochemiluminescent and Photoelectrochemical Bioanalysis
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In this feature, electrochemiluminescent (ECL) and photoelectrochemical (PEC) properties and mechanisms of semiconductor quantum dots (QDs) are reviewed, with emphasis on their specific fundamentals and concise comparison on their similarities and differences. With recent illustrative examples of bioanalytical applications, the main signaling strategies for QDs-based ECL and PEC bioanalysis are then highlighted. The future prospects in this field are also discussed. More


Building a Better Liposome
Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Using computational modeling, researchers at Carnegie Mellon University, the Colorado School of Mines and the University of California, Davis have come up with a design for a better liposome. Their findings, while theoretical, could provide the basis for efficiently constructing new vehicles for nanodrug delivery. Liposomes are small containers with shells made of lipids, the same material that makes up the cell membrane. More


Olefin Oxygenation by Water on an Iridium Center
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Oxygenation of 1,5-cyclooctadiene (COD) is achieved on an iridium center using water as a reagent. A hydrogen-bonding interaction with an unbound nitrogen atom of the naphthyridine-based ligand architecture promotes nucleophilic attack of water to the metal-bound COD. Irida-oxetane and oxo-irida-allyl compounds are isolated, products which are normally accessed from reactions with H2O2 or O2. DFT studies support a ligand-assisted water activation mechanism. More


New Papers Discuss Details for Possible 'Exercise Pill'
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Two recently published papers have laid the groundwork for creating a potential "exercise pill." The first paper was published Oct. 2 in the journal Cell Metabolism. Researchers from the University of Sydney and University of Copenhagen employed a technique called mass spectrometry to analyze the protein changes skeletal tissue after exercising. The test subjects for this experiment were four healthy males who had a muscle biopsy before exercise, writes Quartz. More


Mini-Kidneys From Stem Cells
The Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In a time when organoids are becoming commonplace in the lab, a research team from Australia and the Netherlands has successfully generated structures that resemble embryonic kidneys from human stem cells. In addition to being a step in the right direction for eventual lab-grown kidneys for transplant, the structures could help scientists screen drugs for toxicity and model normal and diseased kidney function, the authors argue in Nature. More


Chemistry Controls Magnetism
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Magnets are well-known from the physics lessons at school, but they are hardly covered in chemistry lectures; and it is still a chemical process by means of which researchers have succeeded in controlling magnetic properties in bulk ferromagnets. While physical processes may influence the orientation of the magnetic fields, the chemical process in this case controls magnetism in carefully chosen strongly ferromagnetic material systems. The working principle used in this case is similar to the concept of lithium-ion batteries. More


Career


Senior Automation Engineer
Crescendo Bioscience
US – CA – South San Francisco

Automation Engineer, R&D
Dow AgroSciences, LLC
US – IN – Indianapolis

Postdoctoral Position in Microglia Biology & Redox Signaling
Indiana University School of Medicine & the Stark Neuroscience Research Institute
US – IN – Indianapolis

More jobs at SLAS Career Connections


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