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SLAS announces Asia
office and conference
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To support its growing membership in Asia, SLAS has opened a member services office in
Shanghai, China. The Society also set the 2012 SLAS Asia Conference and Exhibition for June 19-21 in Shanghai.
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Oct. 31 deadline for SLAS2012 registration discounts
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Save money and ensure your place at the First Annual SLAS Conference and Exhibition on Feb. 4-8 in San Diego. Experience the best in laboratory science and technology, and enjoy evenings filled with special SLAS2012@Night events.
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DARPA award to JALA Editorial Board member
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Recognizing his work on new physical methods for biological characterization and control, Dino Di Carlo received a Young Faculty Award from the Defense Advanced Research Projects Agency. Di Carlo is assistant professor of bioengineering at UCLA.
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Innovation AveNEW applications due Oct. 25
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Entrepreneurs: Take advantage of this cost-sensitive program allowing startup companies to engage with the world-class SLAS2012 audience in
San Diego. Apply today.
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We offer the industry’s largest human and ortholog GPCR stable cell
line collection and hundreds of customizable options for your functional and binding screening and profiling needs, with the highest quality and fastest turnaround. More>> Email: info@multispaninc.com |
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LabAutopedia video in honor of Jim Little
LabAutopedia Share
  
This month's LabAutopedia home page video features a Zymate robot in honor of former Zymark founder Jim Little, who passed away in September.
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Tackling Chemical Space: All Hands on Deck
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A new SLAS Electronic Laboratory Neighborhood feature explores various strategies to attain the best possible starting point for successful drug discovery. Take a look.
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Do less and get more from your kinetic
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SRU Biosystems has introduced the first and only high resolution, optical, label-free plate reader. Capable of measuring functional responses in individual cells, the SCANNER represents a
new paradigm in drug discovery enabling the use of primary cells earlier in drug discovery process. Contact us to learn more.
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Ultra Low Attachment Surface plates feature a covalently bound
hydrogel layer that effectively inhibits cellular attachment, minimizes protein absorption, enzyme activation, and cellular activation. Corning® introduces 384 well black clear bottom Ultra Low Attachment Surface plates for HTS applications of tumor spheroid and stem cell embryoid body screening.
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Stanford scientists using phosphoprotein profiling to predict oncogene addiction, drug response
ProteoMonitor Share
  
A team led by Stanford University researchers has developed a method for predicting response to cancer therapies based on cellular signaling protein dynamics and changes in tumor size.
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Mechanistic insights for block copolymer morphologies: How do worms form vesicles?
Journal of the American Chemical Society Share
  
Amphiphilic diblock copolymers composed of two covalently linked, chemically distinct chains can be considered to be biological mimics of cell membrane-forming lipid molecules, but
with typically more than an order of magnitude increase in molecular weight. These macromolecular amphiphiles are known to form a wide range of nanostructures (spheres, worms, vesicles, etc.) in solvents that are selective for one of the blocks.
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Nature Middle East is a FREE resource for scientists and clinicians to connect, research, network and exchange information and ideas. Sign up to the latest research coming out of the Arab world and become
part of the of Nature Middle East community.
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Scientists correct the typo behind a genetic liver disease
Discover Magazine Share
  
Every year, thousands of people die because of typos in their genes. There's a long list of debilitating or fatal genetic diseases that are caused by a single incorrect DNA letter
among the three billion in our genome. It's the equivalent of pulping an entire encyclopedia on the basis of a single typo. But hope is at hand. We are fast approaching the point when we can proofread these errors out of our genes.
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MICROLAB® NIMBUS, first in a new class of personalized pipetting workstations, offering speed, flexibility, performance and affordability, all in a compact, space-efficient footprint. MORE |
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Scientists develop nanochannel electroporation device for precise control of transfection into individual cells
Genetic Engineering & Biotechnology News Share
  
Scientists report on the development of a nanochannel electroportation device that can deliver precisely monitored amounts of either large or small transfection agents into individual living cells, without affecting cell viability. The approach effectively involves capturing a cell in a microchannel abutting a nanochannel, and then generates an intense
electric field over a very small area on the cell membrane.
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Probing how strong lasers stabilize electrons
Proceedings of the National Academy of Sciences Share
  
Intuitively, a strong laser pulse should blast electrons away from atoms, but theory suggests that intense fields can work with the forces within an atom to stabilize electrons. The concept of a laser-stabilized Kramers–Henneberger atom stimulated an initial burst of research, but interest in the concept gradually waned in the absence of supporting experimental evidence.
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SCINOMIX’S SCI-PRINT VX2 is a small footprint multifunction vial handling system. The SCI- PRINT MP2+ is a
high throughput fully automated barcode label printer for microtiter plates and deep well blocks. Click here to see product videos and more! |
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Single-electrolyte isotachophoresis using a nanochannel-induced depletion zone
Analytical
Chemistry Share
  
Isotachophoretic separations are triggered at the border of a nanochannel-induced ion-depleted zone. This depletion zone acts as a terminating electrolyte and is created by
concentration polarization over the nanochannel. We show both continuous and discrete sample injections as well as separation of up to four analytes.
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Pharmaceutical firms shift business to generics and emerging markets
Chemical & Engineering News Share
  
Names such as Pfizer, Merck & Co., and GlaxoSmithKline have long been synonymous with the discovery and sale of proprietary, high-priced small-molecule drugs. But the realities of healthcare markets are leading many firms to broaden their definitions of what they do. As conventional markets wane and new geographies emerge, many of the biggest companies are outlining new strategies.
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The nonproton ligand sensing domain is required for paradoxical stimulation of ASIC3 channels by amiloride
The Journal of Biological Chemistry Share
  
Acid-sensing ion channels, which belong to the epithelial sodium channel/degenerin family, are activated by extracellular protons and are inhibited by amiloride, an important pharmacological tool for studying all known members of ENaC/DEG.
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The MaxCyte STX enables rapid, large-scale transfection of cell lines, primary cells, and other difficult-to-transfect cells for use in cell-based functional assays. Power up your high throughput GPCR functional screening by transfecting up to 1E10 cells in less than 30 minutes.
Learn more about MaxCyte STX Transfection for GPCR Assays.
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Thermo Scientific Orbitor KingFisher Flex Extraction Workstation allows users to extract more nucleic acids/proteins in less time. The small, easy-to-use solution provides
unattended walk-away time, better control of processes and greater sample consistency combined with an audit trails of all operations performed (time-stamped, stored records). Contact us to learn more.
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The comPOUND system comprises a high-density sample storage unit and an additional suite of specialized delivery and processing modules to enable easy integration into any compound management or screening system.
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Hardware for sub-micron micropositioning &
microscopy. Products include XYZ stages, Piezo stages, Optics, Microscopy, & Turnkey systems built to user specifications. We utilize long life components for demanding OEM applications.
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Venenum BioDesign specializes in HTS of 5.5 million compounds including new libraries for protein-protein interactions. MORE
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JBS is the leading peer-reviewed journal focused on drug discovery sciences.
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The SLAS Market Place offers access to new and existing technology products and services for your laboratory.
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