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Certified UPS’s to protect your laboratory’s critical instrumentation and resolve current and potential power issues.
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See how the Thermo Scientific Versette automated liquid handler can meet your liquid handling needs!
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The SLAS Market Place offers access to new and existing technology products and services for your laboratory.
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46 students from 10 countries earn SLAS Tony B. Academic Travel Awards
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In service of its educational mission and to serve life sciences R&D professionals around the world, SLAS honors 46 undergraduate students, graduate students, post‐doctoral researchers and junior faculty members with SLAS Tony B. Academic Travel Awards for SLAS2014, Jan. 18‐22, 2014, San Diego, CA. Awards include roundtrip travel, hotel and conference registration. A panel of judges evaluated student abstract proposals and made selections based on scientific merit.
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Oct. 28 deadline: SLAS2014 Student Poster Competition and all poster abstracts
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| SLAS2013 student poster winners |
The SLAS2014 Student Poster Competition recognizes innovative research by students, graduate students, post-doctoral associates and junior faculty.
The top three earn cash awards of $500.
Additionally, Monday, Oct. 28, is the deadline for all poster abstract submissions to be judged and, if selected, included in the SLAS2014 Final Program.
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Become an SLAS member this month and get 15 months for the price of 12!
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SLAS memberships typically coincide with the calendar year, from January to December. But join SLAS now and receive all member benefits starting immediately — SLAS2014 registration discounts, journal subscription(s), Nov. 12 and Dec. 5 phenotypic drug discovery webinars for example — through December 2014.
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JALA Online features new manuscripts ahead-of-print
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"Exclusion-Based Capture and Enumeration of CD4+ T Cells from Whole Blood for Low-Resource Settings," "Automation of 3D Cell Culture Using Chemically Defined Hydrogels" and "Droplet Array Platform for High-Resolution Melt Analysis of DNA Methylation Density" are among the new manuscripts available only to SLAS Laboratory Automation Section members and JALA subscribers ahead-of-print.
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Let Multispan be your one-stop shop partner from cell line and
assay development to screening, lead optimization and
profiling - reduce your cycle time to IND.
More>> Email: info@multispaninc.com
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Life Chemicals specializes in organic synthesis for Drug Discovery. We provide compound libraries for HTS, collections of fragments, targeted libraries, building blocks and custom synthesis services.
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Oct. 31 deadline for SLAS2014 discounts
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Save up to $300 on your SLAS2014 participation by registering before the end of this month!
An outstanding scientific program of 132 podium sessions, 400-plus poster presentations and 17 Short Courses across seven in-depth tracks headlines the Jan. 18-22 event in San Diego.
See the SLAS2014 preliminary program for more information.
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Weigh the substance AND the solvent using Quantos automated dispensing systems from METTLER TOLEDO. Preparing accurate concentrations using gravimetric dosing complies with the latest USP guidelines <841>. It offers the benefits of improved quality of results; enhanced user safety; guaranteed process security; and minimized substance and solvent consumption.
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The xCELLigence RTCA-DP System monitors cell migration/invasion using a noninvasive label-free impedance-based technology. This walk-away system allows you to measure cell invasion and migration continuously in real time over the entire time course of an experiment. Visit us at www.aceabio.com.
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Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.
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LabAutopedia Book of the Month: Probably Approximately Correct
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Harvard computer scientist Leslie Valiant offers "probably approximately correct" algorithms to explain how effective behavior can be learned to help us survive and prosper in our complex world. New York Times book columnist Edward Frenkel says, "The book is written in a lively, accessible style and is surprisingly entertaining. It's funny how your perception of even mundane tasks can change after reading it — you start thinking algorithmically, confirming Dr. Valiant's maxim that computer science is 'more about humans than about computers.'"
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Complete the 2013 SLAS Membership Survey
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SLAS members: ensure SLAS knows what matters most to you. Respond to the 2013 membership survey before Oct. 31.
All who complete the survey are eligible for a Sweepstakes Drawing featuring some terrific prizes, including an expense-paid trip to attend SLAS2014.
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Automated digital microfluidic platform for magnetic-particle-based immunoassays with optimization by design of experiments
Analytical Chemistry Share
  
We introduce an automated digital microfluidic platform capable of performing immunoassays from sample to analysis with minimal manual intervention. This platform features (a) a 90 Pogo pin interface for digital microfluidic control, (b) an integrated (and motorized) photomultiplier tube for chemiluminescent detection, and (c) a magnetic lens assembly which focuses magnetic fields into a narrow region on the surface of the DMF device, facilitating up to eight simultaneous digital microfluidic magnetic separations.
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Physical cues help mature cells revert into stem cells
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Bioengineers at the University of California, Berkeley, have shown that physical cues can replace certain chemicals when nudging mature cells back to a pluripotent stage, capable of becoming any cell type in the body. The researchers grew fibroblasts — cells taken from human skin and mouse ears — on surfaces with parallel grooves measuring 10 micrometers wide and 3 micrometers high.
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China's pharma boom
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Because of considerable investment in China's pharmaceutical research and development sector, along with numerous government-initiated reforms, the Chinese pharmaceutical market value is projected to reach $315 billion by 2020. That would represent more than 650-percent revenue growth, according to a new report from research and consulting firm GlobalData, which also projects that China's medical device market will grow to $54 billion by same year.
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Scigilian is a software company specializing in offering solutions to the problems encountered in pharmaceutical research, biotechnology, and contract research. Trusted, from large pharma to small CRO.
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Discovery of a substrate selectivity motif in amino acid decarboxylases unveils a taurine biosynthesis pathway in prokaryotes
ACS Chemical Biology Share
  
Taurine, the most abundant free amino acid in mammals, with many critical roles such as neuronal development, had so far only been reported to be synthetized in eukaryotes. Taurine is the major product of cysteine metabolism in mammals, and its biosynthetic pathway consists of cysteine dioxygenase and cysteine sulfinic acid decarboxylase.
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Virus-sabotaging protein may help people defy HIV
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In a small number of people infected with HIV, the virus is naturally suppressed without medical treatment — and we might be closer to understanding why. They may carry high quantities of a protein that disrupts viral replication in cells. Called APOBEC3G, or "A3" for short, the protein sabotages reverse transcription, the process HIV relies on for its replication.
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Production of non-toxic flame retardants simplified
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Electronics, vehicles, textiles — almost all modern-day products contain some form of plastic. Its high combustibility means it must be protected from naked flames. New techniques simplify the production of environmentally friendly flame retardants. Alarmingly, some 600 people die in household fires in Germany every year. Often started by nothing more than a small tea light, such fires can soon take hold.
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Targeting mitochondrial ROS: A novel therapy for a number of diseases
By Dr. Afsaneh Motamed-Khorasani Share
  
Reactive oxygen species, or ROS, are generated in a number of physiological reactions in our body. They are responsible for a number of diseases, such as cancer, inflammatory, autoimmune and neurodegenerative disorders. Currently, an effective antioxidant therapy is not available. Therefore, an in-depth knowledge of the mechanisms responsible for the production of ROS and their role in the inflammation pathways is critical for the development of new drugs. Recent publications have demonstrated that the ROS derived from mitochondria were responsible for the up-regulation of cytokines through a number of signal transduction pathways.
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Toward a more water-based chemicals industry
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While all areas of human activity have an impact on the environment, the chemicals industry is often singled out as a particularly poor environmental performer, associated with high energy consumption and the generation of large quantities of toxic waste products. Thus, as chemical production continues to increase, the global industry faces both economic and environmental pressures, and growing regulatory constraints.
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Capturing carbon dioxide with a small pH change
Chemical & Engineering News Share
  
Coal-fired power plants produce one-third of the carbon dioxide emissions in the U.S. Scientists have been developing strategies to capture this carbon and prevent its release into the atmosphere, in hopes of curbing global climate change. But so far, those methods are too expensive to implement because of their high energy requirements. Now, researchers report a novel electrochemical method that could capture CO2 using less energy.
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BMG LABTECH is releasing its newest instrument, the CLARIOstar, a high performance microplate reader with advanced monochromators, spectrometer, and filters. With this cutting-edge, hybrid technology, the CLARIOstar offers clear superiority with unparalleled flexibility and sensitivity.
Anything is possible with BMG LABTECH’s CLARIOstar. Any wavelength. Any bandwidth. Any assay.
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Introducing AusWasher MTP, a plate washer with residual volume < 0.01µl, enabling the highest specificity ELISA in 96, 384,1536 well plates with dramatically reduced number of wash steps. Centrifugation eliminates aspiration of wash buffer: no clogging, uniform buffer removal, no damage from physical contact with needles. Available standalone and OEM.
Info: Wolfgang Mann wmann@ausbio.de
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The Prestwick Chemical Library moves into its 14th year of leading the industry with its collection of 1,280 approved drugs available in multiple formats. Applications range from assay development and calibration to single substance and combination screens. Prestwick also provides follow-up chemistry services for lead discovery and optimization.
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SLAS Point-to-Point
Colby Horton, Vice President of Publishing, 469.420.2601 Download media kit
Dennis Hall, Senior Content Editor, 469.420.2656 Contribute news
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