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  Mobile version   RSS   Subscribe   Unsubscribe    SLAS2012   Moving? New job? Let SLAS know.    Oct. 26, 2011




Innovation in Education: Bridging the Gap
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A new SLAS Electronic Laboratory Neighborhood feature discusses how colleges and universities are tailoring courses in business essentials to address the needs of life sciences companies. More

Oct. 31 deadline for SLAS2012 registration discounts
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Reserve your place at the First Annual SLAS Conference and Exhibition on Feb. 4-8 in San Diego and save money, too. Explore the SLAS2012 preliminary program for details on the powerful scientific program. More

Small automated pipettors perform big
SOLO & SOLOPlus Automated Pipettors are the perfect choice for automating repetitive and time consuming applications. Available in single channel, 8-channel and 12- channel configurations the SOLO handles serial dilutions, kinase assays and next-gen sequencing prep with ease. Multiple deck configurations, accessories and robotics are available. See more at Email

First chemical space module sparks interest
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Chris Lipinski opened the four-part SLAS virtual course, "Interrogating Chemical Space — Rules, Filters, Fragment-Based Screening and Beyond," on Oct. 25. Next modules are set for Nov. 1, Nov. 8 and Nov. 15. More


SLAS president discusses presence in Asia
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"This is another exciting moment in SLAS history," says SLAS President Michelle Palmer about the opening of an SLAS office in Asia and the June 19-21, 2012, dates for its second China conference. More

Screen Your Compounds at Multispan

In human and ortholog GPCR stable cell lines in Calcium, cAMP, IP-1, GTPγS, ligand-binding and internalization assays, offering the fastest turnaround, highest quality and most diversity. More>>

Enter the JALA and JBS Art of Science Contest
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Share your mesmerizing original scientific images with SLAS by Dec. 2, and you might win an iPad 2 or one of ten $50 Amazon gift cards! More

SLAS365: Value all year round
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It's SLAS membership renewal time. Reply now to stay connected with the international laboratory science and technology community. Remember, members receive discounts on SLAS2012 registration and other SLAS programs. More
Fifteen Minute
ELISA Assays
Do less and get more from your ELISAs

• Quantitate 96 protein samples in 15 minutes, not hours
• Take advantage of a 4-log dynamic range and dilute less
• Analyze crude samples with less prep
• Get information-rich direct binding data, not end-point results
• Develop new assays in a few hours, not weeks

Octet Systems with Dip and Read assays. No hassle, label-free ELISAs.

Contact us to learn more.
Introducing the BIND® SCANNER from SRU Biosystems
SRU Biosystems has introduced the first and only high resolution, optical, label-free plate reader. Capable of measuring functional responses in individual cells, the SCANNER represents a new paradigm in drug discovery enabling the use of primary cells earlier in drug discovery process. Contact us to learn more.
Scale-up Ion Channel Expression using MaxCyte Transfection
Express multi-subunit ion channels with ease including toxic or previously intractable channels using the proven MaxCyte® STX™ Scalable Transfection System. Scale-up your automated electrophysiology and calcium flux screening assays by transfecting up to 1E10 cells in less than 30 minutes!
Find out more about MaxCyte Large Volume Transfection.


Label-free cell-based assays using photonic crystal optical biosensors
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Biosensor technologies that have been primarily used in the past for characterizing biomolecular interactions are now being used to develop new approaches for performing cell-based assays. Biosensors monitor cell attachment to a transducer surface, and thus provide information that is fundamentally different from that provided by microscopy. More


On the selective ion binding hypothesis for potassium channels
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The mechanism by which K+ channels select for K+ over Na+ ions has been debated for the better part of a century. The prevailing view is that K+ channels contain highly conserved sites that selectively bind K+ over Na+ ions through optimal coordination. More


Nature Middle East is a FREE resource for scientists and clinicians to connect, research, network and exchange information and ideas. Sign up to the latest research coming out of the Arab world and become part of the of Nature Middle East community.

You can also follow Nature Middle East on Facebook and Twitter.

Robots to help children with autism
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An endearing little robot named Bandit may be the newest technology to help children with autism better understand social cues and emotional behavior. Researchers at the Robotics Research Lab at University of Southern California have created studies for children with autism to interact and play with Bandit, a small human-like robot with movable eyebrows and mouth, and motion sensors that allow him to back away or move forward. More

NIMBUS Personalized Pipetting Workstation

MICROLAB® NIMBUS, first in a new class of personalized pipetting workstations, offering speed, flexibility, performance and affordability, all in a compact, space-efficient footprint.

New role for vascular endothelial growth factor in regulating skin cancer stem cells
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In a study published in Nature, researchers identify a new role for vascular endothelial growth factor in regulating skin cancer stem cells. The study was lead by Cédric Blanpain, Welbio investigator at Université Libre de Bruxelles, in collaboration with the groups of Peter Carmeliet (VIB/K.U.Leuven) and Jody J. Haigh (VIB/UGent). The results could have important implications for the prevention and treatment of different epithelial cancers. More


Ligand-binding domain of an α7-nicotinic receptor chimera and its complex with agonist
Nature Neuroscience    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The α7 acetylcholine receptor mediates pre- and postsynaptic neurotransmission in the central nervous system and is a potential therapeutic target in neurodegenerative, neuropsychiatric and inflammatory disorders. We determined the crystal structure of the extracellular domain of a receptor chimera constructed from the human α7 AChR and Lymnaea stagnalis acetylcholine binding protein, which shares 64 percent sequence identity and 71 percent similarity with native α7. More


SCINOMIX’S SCI-PRINT VX2 is a small footprint multifunction vial handling system. The SCI- PRINT MP2+ is a high throughput fully automated barcode label printer for microtiter plates and deep well blocks. Click here to see product videos and more!

Glimpsing fusion with the world's fastest light deflector
Science & Technology Review    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Fusion, the world's great promise for a source of clean and virtually limitless energy, could replicate the very process that powers the stars to meet our most pressing needs on Earth. Lawrence Livermore's National Ignition Facility is conducting experiments aimed at achieving fusion ignition and energy gain, the process whereby more energy is released than is required to initiate the fusion reaction. More

A flow cytometry-based assay for screening FimH antagonists
ASSAY and Drug Development Technologies via Liebert Inc.    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Urinary tract infections, including cystitis and pyelonephritis, affect a large proportion of the population and account for significant medical costs. In more than 80 percent of UTIs, uropathogenic Escherichia coli is the causative pathogen. The initial step in the pathogenesis of the infection is the adherence of UPEC to the human bladder epithelium, enabling the invasion into the host cells and the development of UTIs. More

Phthalazinone pyrazoles as potent, selective, orally bioavailable inhibitors of Aurora-A kinase
Journal of Medicinal Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The inhibition of Aurora kinases in order to arrest mitosis and subsequently inhibit tumor growth via apoptosis of proliferating cells has generated significant discussion within the literature. The following study reports a novel class of Aurora kinase inhibitors based upon a phthalazinone pyrazole scaffold. More

Ultra Low Attachment Surface in HTS
Ultra Low Attachment Surface plates feature a covalently bound hydrogel layer that effectively inhibits cellular attachment, minimizes protein absorption, enzyme activation, and cellular activation. Corning® introduces 384 well black clear bottom Ultra Low Attachment Surface plates for HTS applications of tumor spheroid and stem cell embryoid body screening.
DNA Extraction WorkStation

Thermo Scientific Orbitor KingFisher Flex Extraction Workstation allows users to extract more nucleic acids/proteins in less time. The small, easy-to-use solution provides unattended walk-away time, better control of processes and greater sample consistency combined with an audit trails of all operations performed (time-stamped, stored records). Contact us to learn more.
Sample Screening from your Compound
The comPOUND system comprises a high-density sample storage unit and an additional suite of specialized delivery and processing modules to enable easy integration into any compound management or screening system.


Molecular Breeding Lab Lead
USA – CA - Woodland

Scientist III
Boehringer Ingelheim
USA – CT – Ridgefield

Assistant/Associate Professor
The University of Iowa College of Pharmacy
USA – IA – Iowa City

More jobs at SLAS Career Connections





Submicron Motion Control & More

Hardware for sub-micron micropositioning & microscopy. Products include XYZ stages, Piezo stages, Optics, Microscopy, & Turnkey systems built to user specifications. We utilize long life components for demanding OEM applications.


Discovery is our mission...

Venenum BioDesign specializes in HTS of 5.5 million compounds including new libraries for protein-protein interactions.

The SLAS Electronic Laboratory Neighborhood

It's new. It's newsy. And it's available now. Check out this interactive e-zine today.

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Boost your career or find the perfect candidate. SLAS Career Connections offers both online and in-person career services.

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