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SLAS ELN Reports: Left Brain, Right Brain, Happy Accidents and the JALA & JBS Art of Science Contest
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"Whether they're the result of careful planning or just happy accidents, laboratory research often yields striking and beautiful images that we just can't take our eyes off," says SLAS President Daniel G. Sipes in his latest column in the SLAS Electronic Laboratory Neighborhood. "These are the images JALA and JBS celebrate with the JALA & JBS Art of Science Contest. The due date for 2015 entries is December 24, 2014. I encourage you to think back at what crossed your benchtop this past year. If a particular cell structure, assay result or other lab creation comes to mind, it probably would be a great entry into this contest. Go for it!"
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JALA Special Issue Call for Manuscript Proposals: Advancing Scientific Innovation with Acoustic Droplet Ejection
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Guest Editors Clive Green, Ph.D.; Lynn Rasmussen; and Joe Olechno, Ph.D., invite manuscript proposals by Oct. 31 on topics related to the use of acoustic droplet ejection (ADE) in drug discovery and the biological sciences. Areas of interest include physics of ADE, ADE in combination drug therapy, ADE in cell-based analyses, ADE in protein crystallography and ADE in combinatorial chemistry. SLAS members and nonmembers alike are welcome to submit proposals.
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Reminder: Oct. 31 is SLAS2015 Early-bird Registration Deadline
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Take advantage of deepest discounts for SLAS2015 when you register by Friday, Oct. 31.
This early-bird discount is exclusively for dues-paying members of SLAS.
You can join SLAS, or renew your member dues, during the SLAS2015 registration process.
SLAS2015 will be held Feb. 7-11 in Washington, D.C.
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SLAS Asia Antibody Discovery Seminar Celebrates Success
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More than 140 researchers from contract research organizations, pharmaceutical companies and academic institutions participated in the one-day seminar Oct. 23. SLAS Asia presented the educational event in partnership with the Shanghai Institute for Advanced Immunochemical Studies of ShanghaiTech University. Sessions included:
- Cell Based Hybridoma Screening for Therapeutic Antibody Discovery
- A De Novo Antibody Fab Library Using Phage pIX Display
- Combinatorial Antibody Library, Theory & Applications
See photos on Facebook.
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Discover SLAS through the Words and Experience of its Members
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A new SLAS video series brings you face-to-face with several different people and priorities that comprise the SLAS community. Learn from 13 life sciences R&D professionals from academia and industry, from the U.S. and abroad, as they explain how SLAS membership pays them back personally and professionally.
"SLAS helps make my research better by making it more applicable and practical," says Dino Di Carlo of the University of California, Los Angeles. "SLAS is really open and friendly — you don't feel refrained from asking questions," says Sabrina Corazza of Axxam.
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Talking All Things Ebola with Laurie Garrett
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Laurie Garrett, SLAS2015 keynote speaker, is featured on the Oct. 20 Humanosphere podcast with Tom Paulson and Gabe Spitzer.
When asked how the Ebola outbreak spun out of control and got so big, Garrett responded, "You know, we had a set of factors line up in a way that I haven't seen since the early days of HIV, and a lot of similar, in an abstract sense, very similar patterns of problems. The first was the virus emerged in an area that had never seen Ebola before, either in animals or humans, so there was no sense of alarm. It wasn't on anybody's radar screens."
Listen to the other factors; the interview with Garrett begins at about 9:25 in the podcast.
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White House Halts Gain-of-Function Research
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While it reviews safety procedures, the White House is temporarily shutting down all federal research exploring how certain viruses and bacteria become more dangerous. "During this pause, the National Institutes of Health will not provide new funding for any projects involving these experiments," NIH Director Francis S. Collins says.
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Protein Discovery May Unlock New HIV Treatment
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Like a slumbering dragon, HIV can lay dormant in a person's cells for years, evading medical treatments only to wake up and strike at a later time, quickly replicating itself and destroying the immune system.
Scientists at the Salk Institute have uncovered a new protein that participates in active HIV replication, as detailed in the latest issue of Genes & Development.
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Scientists Create New Protein-Based Material With Some Nerve
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UC Berkeley scientists have taken proteins from nerve cells and used them to create a "smart" material that is extremely sensitive to its environment. This marriage of materials science and biology could give birth to a flexible, sensitive coating that is easy and cheap to manufacture in large quantities.
The work, published in the journal Nature Communications, could lead to new types of biological sensors, flow valves and controlled drug release systems, the researchers said.
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Protein Fiber Engineered for First Time on the Microscale
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Scientists at the New York University Polytechnic School of Engineering say they have made a major advance in the development of proteins that form specialized fibers used in medicine and nanotechnology. For as long as scientists have been able to create new proteins that are capable of self-assembling into fibers, their work has taken place on the nanoscale.
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Study Investigates Inherent Contamination in Deep Well Microplates
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A recent study by the Department of Chemistry at the University of Kent, U.K., provides a detailed analysis of deep well microplates and the significant levels of contamination found in more than 50 percent of the commercially available plates tested. The study, following on from an earlier study in 2005, gives data on a large range of microplates from numerous manufacturers based in Europe, the United States and China.
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More Predictive Model for Early Stage Cancer Therapeutics Screening
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A new application report introduces a more predictive and realistic model for early stage drug screening of cancer therapeutics.
The report shows that incorporating vascular and stromal cells with breast cancer tumor spheroids allows them to more closely mimic the extracellular environment, cellular architecture and behavior of actual tumors; this triculture promotes growth, invasion and endothelial recruitment.
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Microfluidic Assay for Continuous Bacteria Detection Using Antimicrobial Peptides and Isotachophoresis
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We present a novel microfluidic assay for continuous and quantitative detection of bacteria in water. We leverage isotachophoresis (ITP), an electrophoretic focusing technique, to create a stationary high concentration zone of fluorescently labeled antimicrobial peptides (AMPs) in a microfluidic channel.
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Researchers Discover How Microbes Build a Powerful Antibiotic
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Researchers report in the journal Nature that they have made a breakthrough in understanding how a powerful antibiotic agent is made in nature. Their discovery solves a decades-old mystery, and opens up new avenues of research into thousands of similar molecules, many of which are likely to be medically useful.
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This is What Brain Cell Conversations Look Like
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Call them the neuron whisperers. Researchers are eavesdropping on conversations going on between brain cells in a dish. Rather than hearing the chatter, they watch neurons that have been genetically modified so that the electrical impulses moving along their branched tendrils cause sparkles of red light. Filming these cells at up to 100,000 frames a second is allowing researchers to analyze their firing in unprecedented detail.
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How Cells Know Which Way to Go
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Amoebas aren't the only cells that crawl: Movement is crucial to development, wound healing and immune response in animals, not to mention cancer metastasis. In two new studies, researchers answer long-standing questions about how complex cells sense the chemical trails that show them where to go — and the role of cells' internal "skeleton" in responding to those cues.
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SLAS Point-to-Point
Colby Horton, Vice President of Publishing, 469.420.2601 Download media kit
Dennis Hall, Executive Editor, 469.420.2656 Contribute news
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