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SLAS
At the top of your "To Do" list today: Make plans for SLAS2019 (Feb. 2-6 in Washington, D.C., USA)! Today is the final day to take advantage of the Member-Only Registration Discount to save $90 off the early-bird discount rate. It's also the deadline to submit an abstract for the SLAS Ignite Academic Collaboration Presentations, an opportunity to present your academic research in order to find collaborative partners among our diverse community of engineers, researchers, scientists, business leaders and pioneering academic experts. Last-but-not-least, this is the final day to apply for SLAS Innovation AveNEW, a program that enables start-up companies to exhibit at SLAS's world-class event free of charge. After completing your tasks, take a moment to build a personalized list of preferred event activities for SLAS2019 using the "My Schedule" function of the newly launched SLAS2019 Event Scheduler. Explore the complete schedule of events, podium presentation abstracts, poster abstracts and image gallery, exhibitor listings and exhibition floor layout!
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SLAS
Thursday, Nov. 1 is the deadline for manuscript proposals (abstracts) for two SLAS Journals Special Issues:
- Membrane Proteins: New Approaches to Probes, Technologies and Drug Design, for publication in a 2019 special issue of SLAS Discovery. Guest Editors Veli-Pekka Jaakola, Ph.D. (NIBR, Switzerland) and Mariafrancesca Scalise, Ph.D. (University of Calabria, Italy) seek abstracts on topics related to developments in membrane protein biology, advances in X-ray crystallography, electron microscopy, assay technologies, expression and purification methods that enable the study of membrane protein targets. Invited submissions will be due March 1, 2019.
- Engineering Innovations for Fundamental Biology and Translational Medicine, for publication in a 2019 special issue of SLAS Technology. Guest Editors S.J. Claire Hur, Ph.D. (Johns Hopkins University) and Deok-Ho Kim, Ph.D. (University of Washington) seek abstracts on topics related to novel analysis and therapeutic methods that synergistically combine micro-/nanoengineering technologies, such as micro-/nanofabrication, microfluidics, nanomaterials, biosensors and imaging techniques for biological specimens to enable fundamental understanding of disease progression, early diagnostics, drug delivery and multiplexed assays. Invited submissions will be due Jan. 1, 2019.
(SLAS Discovery is formerly known as the Journal of Biomolecular Screening. SLAS Technology is formerly known as the Journal of Laboratory Automation.)
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SLAS
"SLAS is a professional society deeply rooted in sharing ideas and information. From its beginning, the SLAS leadership has believed this also means providing for the next generation of leaders," says SLAS President Sabeth Verpoorte, Ph.D., in her latest column in the SLAS Electronic Laboratory Neighborhood e-zine. "The SLAS Grant programs provide much-needed financial assistance to those early in their career and, perhaps more importantly, they grant stellar young scientists access to colleagues who have already navigated some of the early hurdles in the field."
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SLAS
There's still time to register for the inaugural 2018 SLAS Americas Sample Management Symposium, Managing Samples from Bench to Clinic (Nov. 13-14, Boston, MA, USA)! Sample managers working in government, industry or academic research laboratories will experience real world examples, expertise and engaging ideas that advance beyond traditional sample management. Mingle with SLAS sponsors and learn more about new products and services that support life sciences sample management during vendor snapshot presentations to be featured during breaks in the scientific program. SLAS heartily thanks platinum sponsors Evotec, Labcyte, Scigilian and Titian; gold sponsors, Brooks Life Sciences, Hamilton Storage, TTP Labtech and Xavo; and silver sponsor Scinomix.
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Anton Paar’s Modular Sample Processor allows pipetting, sampling, dosing and weighing to be automated. Available as a benchtop unit or a complete solution integration. MORE
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SLAS
Bookmark the SLAS2019 New Products Announcements page to monitor the fast-growing list of products to be unveiled at SLAS2019 in Washington, D.C., USA (Feb. 2-6, 2019). The latest additions to the list include: Abcam PLC (Cambridge, MA, USA) introducing the FirePlex-HT; Greiner Bio-One (Monroe, NC, USA) presenting the M3d 3D Cell Culture; Peak Analysis & Automation (Colorado Springs, CO, USA) revealing the S-LAB; Porvair Sciences (Vineland, NJ, USA) showing the 96-well Krystal 2000 Black and White Plates; MDZ Automation LLC (Bridgeton, MO, USA) highlighting the HTF Plate Dispenser; Sophion Bioscience (Ballerup, Denmark) rolling out the QPatch II; and Stilla Technologies (Villejuif, France) presenting the Opal Chip. SLAS2019 exhibitors: Add your new product launch to the list!
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SLAS
If you haven't been to the SLAS Electronic Laboratory Neighborhood e-zine lately, find out what's new:
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Journal of the American Chemical Society
A major challenge in performing reactions in biological systems is the requirement for low substrate concentrations, often in the micromolar range. Researchers report that copper cross-linked single-chain nanoparticles are able to significantly increase the efficiency of copper(I)-catalyzed alkyne–azide cycloaddition reactions at low substrate concentration in aqueous buffer by promoting substrate binding.
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Lab Manager
The century-old mission to understand how the proteins responsible for amyloid-based diseases such as Alzheimer's, Huntington's and Parkinson's work has taken major steps forward in the last 12 months, thanks to a revolution in a powerful microscopy technique used by scientists.
High-powered microscopes using electrons instead of light to "see" the actual shape of samples put under them at near atomic-levels of detail have only recently become available to UK scientists.
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Chemistry & Engineering News
When scientists talk about druggable targets, they're usually referring to proteins. But a new report confirms that RNA's tertiary structure could also provide a rich vein of druggable biomolecules. Yale University's Anna Marie Pyle and coworkers reasoned they could come up with druglike molecules by taking aim at the mitochondrial RNA tertiary structure known as self-splicing group II intron.
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Phys.org
Many drugs today are produced as powdered solids. But to fully understand how the active ingredients will behave once inside the body, scientists need to know their exact atomic-level structure. For instance, the way molecules are arranged inside a crystal has a direct impact on a compound's properties, such as its solubility. Researchers are therefore working hard to develop technologies that can easily identify the exact crystal structures of microcrystalline powders.
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Science Daily
A NIMS-Ehime University joint research team succeeded in discovering new materials that exhibit superconductivity under high pressures using materials informatics approaches (data science-based material search techniques). This study experimentally demonstrated that MI enables efficient exploration of new superconducting materials. MI approaches may be applicable to the development of various functional materials, including superconductors.
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Laboratory Equipment
Worldwide, resistance to antibiotics is on the rise. In order to understand why bacteria are becoming immune to previously well-functioning drugs, scientists are penetrating ever deeper into the molecular structure of cells.
A research group at Martin Luther University Halle-Wittenberg has now succeeded in isolating a membrane protein from the E. coli bacterium, shedding light on its molecular structure.
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Genetic Engineering & Biotechnology News
Scientists at the University of California San Diego have identified a gene that is involved in controlling the sensitivity of cancer cells to DNA-damaging agents. Their investigations found that the Schlafen 11 protein impacts on the function of the protein serine/threonine kinases ATM and ATR — which play key roles in cells' DNA damage response — by cleaving the transfer RNA (tRNA) tRNA-Leu-TAA.
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The Scientist
A defining shift in molecular biology over the past decade has been the application of whole genome and whole transcriptome sequencing methods to single cells. With advances in cell isolation and next generation sequencing, researchers no longer need to average out the signal from multiple cells in a population, but can instead study the DNA, RNA, proteins and chromatin cell by cell.
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Job Seekers: Post your résumé and sign up for new job alerts by keyword.
Employers: Search résumés, post an open position, internship or post-doc opportunity. SLAS Premier and Corporate Members get a discount on all new job postings.
Lab Automation Engineer 2-3
Calico
US – CA – South San Francisco
Postdoctoral Scientist – Pulmonary Research
Cedars-Sinai
US – CA – Los Angeles
Research Assistant II
Vanderbilt Health
US – TN – Nashville
SLAS Discovery / SLAS Technology Publishing Manager
SLAS
US – IL – Oak Brook
Search Jobs at SLAS Career Connections
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