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SLAS Board of Directors election
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Learn more about the eight candidates in the race for three positions on the 2013 SLAS Board of Directors. All dues-paid SLAS members will receive a ballot with voting instructions via e-mail today. Voting ends Dec. 3, 11:59 p.m. central standard time. Questions? Contact Mary Geismann. More

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SLAS2013 short courses extend learning
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Based on registrations to date, SLAS2013 short courses are in high demand this year. From "Introduction to Design of Experiments" to "Next Generation Sequencing Technology Fundamentals and Applications" to "Introduction to Laboratory Automation," SLAS2013 short courses allow focused study in small groups with expert instructors. Space in each is limited, so register today. More

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SLAS LinkedIn group exceeds 4,000 members
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Congratulations and welcome to Yong Shin, scientist at the Institute of Microelectronics, Agency for Science, Technology and Research (A*STAR) in Singapore, who became member No. 4,000 at SLAS LinkedIn on Nov. 6. Glad you have joined the conversation! More

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Daniel Sipes sails into science
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In the latest SLAS Electronic Laboratory Neighborhood e-zine member profile, read about SLAS Board of Directors member Dan Sipes' uncanny ability to weave personal interests into career opportunities. "It is important to take advantage of various life experiences and apply them in different areas of your life," says Sipes in the e-zine feature story. More

Manuscript proposals now being accepted for JALA and JBS special issues
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Manuscript proposals are now being accepted for three upcoming special issues of JALA and JBS on Phenotypic Drug Discovery (JBS), Advancements in Biomedical Micro/Nano Tools and Technologies (JALA), and New Developments in Global Health Technologies (JALA). More


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SLAS2013 student poster award competition deadline is Nov. 19
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Students, post-docs and junior faculty — submit your innovative work for an opportunity to be seen by 4,500 laboratory science and technology leaders at SLAS2013. Abstracts received after Nov. 19 will not be considered for the student poster award, which includes cash prizes. More

JBS December issue now at JBS Online for members and subscribers
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"Development and Validation of Reagents and Assays for EZH2 Peptide and Nucleosome High-Throughput Screens," "Evaluation of Phosphatidylserine-Binding Peptides Targeting Apoptotic Cells" and "A Multiplexed siRNA Screening Strategy to Identify Genes in the PARP Pathway" are among the original research articles in the December issue. SLAS Biomolecular Sciences Section members can view the issue online now. More


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Enzyme redesign guided by cancer-derived IDH1 mutations
Nature Chemical Biology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Mutations in an enzyme can result in a neomorphic catalytic activity in cancers. We applied cancer-associated mutations from isocitrate dehydrogenases to homologous residues in the active sites of homoisocitrate dehydrogenases to derive enzymes that catalyze the conversion of 2-oxoadipate to (R)-2-hydroxyadipate, a critical step for adipic acid production. More

Crowdsourcing chemistry
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Bruce Parkinson, a chemistry professor at the University of Wyoming, wants to turn sunlight into fuel. All he needs is the right catalyst — a material that would drive the photoelectrolysis of water to make renewable hydrogen fuel and be stable in sunlight for decades. The answer, he's come to believe, is a semiconducting oxide made of several different metals, but the problem is finding the right mix. More



The challenges of the changing drug discovery model
Drug Discovery World    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The drug development industry is restructuring worldwide. This brings different ways of working and new challenges. As the industry moves away from internally focused research to an external model, project management and communication of science will often be more critical than outstanding science. There is a real danger the key skills will be lost across the world, not least in the translation of potential drugs into early clinical trials. More

A major step for fusion energy
Science & Technology Review    Share    Share on FacebookTwitterShare on LinkedinE-mail article
An R&D 100 Award-winning technology will help the world move away from a fossil-fuel-based electricity supply. Sustaining natural resources, reducing carbon emissions, and stabilizing greenhouse gas levels are essential in the face of global warming. One of the most attractive solutions for humankind's future energy needs is controlled thermonuclear fusion. More


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Big data brings big challenges
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Big data and data-enabled science have found their way into the life sciences, bringing challenges that can be summed up in 5 Vs: volume, veracity, velocity, variety and value. Life-sci data are challenging for their variety, value and especially the critical need for veracity — compared with, say, banking, where volume and velocity are the biggest challenges. More

Mass spectrometry today : Fast-growing, innovative, but still somewhat enigmatic
Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The mass spectrometry market continues to be one of the fastest-growing areas of analytical instrumentation. MS's growing popularity can be explained by its ability to provide, in many cases, verifiable molecular weights and thereby positive identification of known molecules. For unknowns, MS fragmentation patterns help scientists piece the molecule of interest together, like pieces of a puzzle. More

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A carbon microthread that makes contact with the mind
MIT Technology Review    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Connecting a human brain to a computer is as much a materials science problem as a biology one. What kind of interface is delicate enough not to damage nerve tissue, but resilient enough to last decades? Researchers have come up with what they call a "stealthy neural interface" made from a single carbon fiber and coated with chemicals to make it resistant to proteins in the brain. More

Stable compounds of oxygen and 'inert' gas xenon predicted
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An international team led by Artem R. Oganov, PhD, a professor of theoretical crystallography in the Department of Geosciences and Department of Physics and Astronomy at Stony Brook University, has established stability of several oxides of normally inert xenon. These compounds are predicted to be stable at high pressures above 830,000 atmospheres, i.e. at pressures corresponding to Earth's mantle and readily achievable in the laboratory. More

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Corals chemically cue mutualistic fishes to remove competing seaweeds
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Corals in the genus Acropora generate much of the structural complexity upon which coral reefs depend, but they are susceptible to damage from toxic seaweeds. Acropora nasuta minimizes this damage by chemically cuing symbiotic goby fishes (Gobiodon histrio or Paragobiodon echinocephalus) to remove the toxic seaweed Chlorodesmis fastigiata. More

The road also taken: Alternative and hidden pathways in biological electron transfer
Phys.org    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Photosynthesis, cellular respiration and many other biological processes have something in common: long-range electron transfer, the simplest known chemical reaction that is known to occur efficiently high over distances up to 20 Å. However, determining the ways in which biological electron transfer is optimized has been a subject of considerable discussion. More


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Career


Lab Automation Expert/Practitioner
Pfizer
USA – CT – Groton

MEG Technologist
Florida Hospital for Children
USA – FL – Orlando

Research Scientist
NYU Langone Medical Center
USA – NY – NY

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