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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit November 15, 2017

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SLAS Announces New Board of Directors and Council Members
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Beginning three-year terms on the SLAS Board of Directors at SLAS2018 are:

  • Emilio Diez Monedero, Chief Scientific Officer, ATLAS Molecular Pharma & Drug Discovery Consultant, Madrid, Spain
  • Peter Brian Simpson, Chief Scientific Officer, Medicines Discovery Catapult, Alderley Park, UK
  • Severine Tamas-Lhoustau, Co-Founder and Managing Partner, Novoptim, Montigny le Bretonneux, France

  • Diez Monedero, Simpson and Tamas-Lhoustau will fill the vacancies created by the completion of terms of current members Scott Atkin, Michele Cleary and Susan Lunte.

    New to the SLAS Americas Council in 2018 are:

  • Mike Berke, Director, Research & Automation Technologies, Amgen, Inc., Thousand Oaks, CA
  • Jonathan O’Connell, Executive Director and Head of Early Discovery, FORMA Therapeutics, Watertown, MA
  • Joe Olechno, Senior Research Fellow, Labcyte Inc., San Jose, CA

  • New to the SLAS Europe Council in 2018 are:

  • Geert Van Minnebruggen, Head of the Science Policy Unit, VIB, Ghent, Belgium
  • Ute Vespermann, Drug Discovery Specialist, Corning Inc., Münster, Germany

  • Welcome! SLAS looks forward to your leadership.
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    NEW and FREE at SLAS Technology: Theranostic Nanoparticles for Tracking and Monitoring Disease State
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    Although the most basic definition of a "theranostic" nanoparticle is a nanoparticle that simply has a therapeutic moiety and imaging or diagnostic moiety on the same particle, the authors of a new SLAS Technology review article pay particular attention to and emphasize the platforms in which self-reporting and disease monitoring is possible in real-time through the synergistic nature of the components on the theranostic particles. The review is organized into theranostic nanoparticles of specific imaging and diagnostic modalities, including optical imaging, magnetic resonance imaging, ultrasound, computed tomography and nuclear imaging.

    Visit SLAS Technology Online to read Theranostic Nanoparticles for Tracking and Monitoring Disease State for free for a limited time. Image by Peter Allen.
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    SLAS2018 Video Previews: Produced by Life Scientists for Life Scientists ...
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    Gain insight from the knowledgeable SLAS2018 presenters offering their expertise as session chairs and subject matter experts. Videos available now are from Automation and High-Throughput Technologies Track Session Chair Shane Horman and Data Analysis and Informatics Track Session Chair Yohann Potier.

    Additional videos will be added to help potential SLAS2018 participants plan their scientific adventures in San Diego.
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    Upcoming SLAS Dates and Deadlines
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    Mark your calendar today!

  • Nov. 17 is the application deadline for the SLAS2018 Late Night with LRIG Rapid-Fire Innovation Session

  • Dec. 1 is the abstract deadline for the 2018 SLAS Europe Compound Management Conference

  • Dec. 8 is the abstract deadline for the 2018 SLAS Europe Conference and Exhibition

  • Dec. 11 is the application deadline for the $100,000 SLAS Graduate Education Fellowship Grant

  • Dec. 12 is the SLAS Webinar: How AstraZeneca is Revolutionizing Sample Management with Acoustic Tube-Based Technologies (free access to all)

  • Dec. 18 is the SLAS2018 advance registration deadline offering discounted rates

  • Jan. 4, 2018 is the deadline to reserve SLAS2018 hotel rooms at the negotiated SLAS2018 rate

  • Jan. 22, 2018 is the final due date for all SLAS2018 poster abstracts

  • Feb. 4, 2018 is the deadline for SLAS2018 New Product Award applications


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    Chemists Unlock the Potential of Fluoroalkenes
    Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    One of the strongest chemical bonds in organic chemistry is formed between carbon and fluorine, giving unique properties to chemical compounds featuring this group. Pharmaceutical researchers are very interested in carbon-fluorine bond containing molecules because of the way they mimic certain behaviors of biological compounds. However, the strength of the carbon-fluorine bond makes it difficult to remove and replace fluorine atoms in a molecule, greatly limiting the structures and types of chemicals that can be made. More


    Bright and Shining Molecules for OLEDs and New Drugs
    Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    Chemists from Ural Federal University (UrFU, Ekaterinburg) have suggested a new technique for synthesizing thiophene derivatives and studied their fluorescent properties experimentally as well as theoretically. Many organic compounds containing thiophene rings exhibit a significant pharmacological activity. Thanks to their unusual electronic nature and low aromaticity, thiophenes are an ideal molecule for synthesizing photoactive polymers, liquid crystals, and organic dyes for solar cells. The researchers described their discovery on the pages of the Chemistry - An Asian Journal. More


    Top 25 Biotech Companies of 2017
    Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    A wave of disappointing third-quarter results and clinical trial failures by the largest biotechs in late October 2017 signaled to some the start of another market swoon, akin to the one that dented share prices starting in late 2015 through 2016. "Biotech Heads for Worst Slump Since 2015 After Disappointing Earnings," predicted a Bloomberg headline on an Oct. 26 story that followed a week of largely bad news. More




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    How Chemists Are Responding to the Opioid Epidemic
    Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    Scroll through your news feed on any given day, and you're bound to come across the latest tragic story emerging from the opioid epidemic. Opioids — including illegal compounds like heroin, synthetic street drugs like fentanyl, and abused prescription painkillers like oxycodone — were responsible for more than half of the roughly 64,000 overdose deaths in the U.S. last year, according to the Centers for Disease Control & Prevention. Overdose deaths from opioids have nearly tripled in the past 15 years. More


    Mobile Platform for Multiplexed Detection and Differentiation of Disease-Specific Nucleic Acid Sequences, Using Microfluidic Loop-Mediated Isothermal Amplification and Smartphone Detection
    Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    New tools are needed to enable rapid detection, identification, and reporting of infectious viral and microbial pathogens in a wide variety of point-of-care applications that impact human and animal health. We report the design, construction, and characterization of a platform for multiplexed analysis of disease-specific DNA sequences that utilizes a smartphone camera as the sensor in conjunction with a hand-held "cradle" that interfaces the phone with a silicon-based microfluidic chip embedded within a credit-card-sized cartridge. More


    Engineering Non-Immune Cells to Kill Cancer Cells
    Phys.org    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    T-cells are one of the immune system's major weapons. They detect the body's cells infected with a virus and trigger their ablation, effectively killing the virus. T-cells cannot do the same with cancer cells, however, as they do not recognize them as foreign cells and are therefore unable to eliminate them. But researchers have recently used T-cells engineered in the laboratory to combat tumors. Modified to include additional functions, these immune cells can hunt down and kill cancer cells. Unfortunately, however, such immune cell therapies can have significant side-effects. More




    Researchers Discover New Mechanism for Battling Influenza
    Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    Just as flu season swings into full gear, researchers from the University of Colorado Boulder and University of Texas at Austin have uncovered a previously unknown mechanism by which the human immune system tries to battle the influenza A virus. The discovery sheds new light on how the virus — which kills 12,000 to 56,000 people in the United States annually — often wins, and it could ultimately lead to new treatments. More


    Targeting Unoccupied Surfaces on Protein-Protein Interfaces
    Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    The use of peptidomimetic scaffolds to target protein–protein interfaces is a promising strategy for inhibitor design. The strategy relies on mimicry of protein motifs that exhibit a concentration of native hot spot residues. To address this constraint, we present a pocket-centric computational design strategy guided by AlphaSpace to identify high-quality pockets near the peptidomimetic motif that are both targetable and unoccupied. More


    Career


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    Princeton University
    US – NJ – Princeton

    Scientists and Directors
    Primary Peptides Inc.
    China – Qingdao

    Post-Doctoral Research Fellow
    Burke Medical Research Institute
    US – NY – White Plains

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