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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit November 16, 2016

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SLAS Member Survey Responses Due Nov. 21
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Your opinion matters! Please respond to the survey currently being conducted to help SLAS understand and prioritize what members need and want in terms of educational programs and member services.

All SLAS members received a link to the survey via e-mail on Nov. 1 (reminder sent Nov. 10). Respond before Nov. 21 and you could be one of three prize winners in the Survey Sweepstakes. Can't find the survey link? Contact Mary Geismann.


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SLAS Nominations Committee Endorses New Members for 2017 SLAS Board of Directors
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The SLAS Nominations Committee endorses Alan Fletcher of PerkinElmer (USA), Cathy Tralau-Stewart of University of California, San Francisco (USA) and Steve Young of Arcus Biosciences for three-year terms of Board service beginning February 2017.

Fletcher, Tralau-Stewart and Young were selected for the breadth and depth of experience they will bring to the SLAS Board of Directors. In accordance with SLAS Policy, if no valid petition nominating alternate candidates is received by Dec. 14, 2016, the appointment of these three individuals will be moved forward to the current Board for official acclamation.
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December Issue Now at JBS Online for Members and Subscribers
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"In Vitro Assays for the Discovery of PCSK9 Autoprocessing Inhibitors," "Functional Characterization of Acetylcholine Receptors Expressed in Human Neurons Differentiated from Hippocampal Neural Stem/Progenitor Cells" and "Matrix-Based Activity Pattern Classification as a Novel Method for the Characterization of Enzyme Inhibitors Derived from High-Throughput Screening" are among the original research articles in the December issue.

Featured on the front cover is a perspective paper providing an overview of knowledge gained in microplate formatting of cellular thermal shift assay and offering a forecast of future applications. SLAS Biomolecular Sciences Section members and JBS subscribers can view the issue online now.
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SLAS Names Vicki Loise Chief Executive Officer
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Following a rigorous executive search, SLAS named Vicki Loise, CMP, CAE as the Society's new CEO. As CEO, Loise will lead the Society's professional team, ensure the Board of Directors' vision is realized and maximize opportunities to fulfill the Society's mission, while maintaining sound business operations and diligent oversight of the Society.

"I'm thrilled to serve as CEO of SLAS," says Loise. "With a foundation that's firmly established and a clear vision forward thanks to the efforts of the Board of Directors, exceptional volunteers and professional team, I believe SLAS is poised for significant growth. I look forward to facilitating that growth, resulting in increased value for our membership, vendor partners and the life sciences discovery and technology community across the globe." Loise takes the helm Jan. 1, 2017.
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Have You Submitted Your $100K SLAS Graduate Education Fellowship Grant Application? Due Today (Nov. 16)
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The SLAS Graduate Education Fellowship Grant Program facilitates educational opportunities for outstanding students pursuing graduate degrees related to quantitative biosciences and/or life sciences research. SLAS awards up to $50,000 per year, for a maximum of two years, to a qualified educational institution on behalf of deserving students enrolled in a graduate program at that institution.

A student's primary research investigator or mentor needs to apply on behalf of the student. Applications for 2017 consideration are due today, Nov. 16, 2016.
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SLAS2017 Short Course Spotlight: High Content Screening - An Introduction to Instrumentation, Assay Development, Screening, Image and Data Analysis
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Course topics include:
  • Introduction to High-Content Analysis and Screening (HCA/HCS)
  • HCS instrumentation overview
  • Reagents and assay development for HCS
  • Image analysis
  • Data management and analysis
  • Case studies of high-content RNAi and small molecule screens
Instructors are Eberhard Krausz of VIB Discovery Sciences and Steffen Jaensch of Janssen R&D, Pharmaceutical Companies of Johnson & Johnson. This is one of 21 short courses to be held at SLAS2017.
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What Election 2016 Means for the Chemistry Enterprise
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The election of Donald Trump as U.S. president and a Republican-controlled Congress portend significant impacts to the chemistry enterprise. Given Republican's campaign statements, academic researchers are likely to feel a federal research funding pinch while the chemical industry could benefit from new energy policies and relaxed regulation. "It is too early to tell what his defined policies and approaches will be toward science," says Glenn S. Ruskin, director of public affairs for the American Chemical Society, which publishes C&EN. More


Slow Motion Waves of Jumping Genes in the Human Genome
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Nature is full of parasites — organisms that flourish and proliferate at the expense of another species. Surprisingly, these same competing roles of parasite and host can be found in the microscopic molecular world of the cell. A new study by two Illinois researchers has demonstrated that dynamic elements within the human genome interact with each other in a way that strongly resembles the patterns seen in populations of predators and prey. More


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A Self-Activated Mechanism for Nucleic Acid Polymerization Catalyzed by DNA/RNA Polymerases
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The enzymatic polymerization of DNA and RNA is the basis for genetic inheritance for all living organisms. It is catalyzed by the DNA/RNA polymerase (Pol) superfamily. Here, bioinformatics analysis reveals that the incoming nucleotide substrate always forms an H-bond between its 3'-OH and β-phosphate moieties upon formation of the Michaelis complex. This previously unrecognized H-bond implies a novel self-activated mechanism (SAM), which synergistically connects the in situ nucleophile formation with subsequent nucleotide addition and, importantly, nucleic acid translocation. More


Researchers Create Synthetic Cells to Isolate Genetic Circuits
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Synthetic biology allows scientists to design genetic circuits that can be placed in cells, giving them new functions such as producing drugs or other useful molecules. However, as these circuits become more complex, the genetic components can interfere with each other, making it difficult to achieve more complicated functions. MIT researchers have now demonstrated that these circuits can be isolated within individual synthetic "cells," preventing them from disrupting each other. More


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Chemists Discover Structure of Bacterial Enzyme That Generates Useful Polymers
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MIT chemists have determined the structure of a bacterial enzyme that can produce biodegradable plastics, an advance that could help chemical engineers tweak the enzyme to make it even more industrially useful. The enzyme generates long polymer chains that can form either hard or soft plastics, depending on the starting materials that go into them. Learning more about the enzyme's structure could help engineers control the polymers' composition and size. More


Detection of Silver Ions Using Dielectrophoretic Tweezers-Based Force Spectroscopy
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Understanding of the interactions of silver ions (Ag+) with polynucleotides is important not only to detect Ag+ over a wide range of concentrations in a simple, robust and high-throughput manner but also to investigate the intermolecular interactions of hydrogen and coordinate interactions that are generated due to the interplay of Ag+, hydrogen ions (H+) and polynucleotides since it is critical to prevent adverse environmental effects that may cause DNA damage and develop strategies to treat this damage. More


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DNA-Based Zika Vaccine Showed Protection From Infection, Brain Damage and Death
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As the global spread of the Zika virus continues, efforts are underway to halt the disease's transmission. While no licensed therapies or vaccines to protect against the Zika virus are currently available, new research published in the journal npj Vaccines demonstrates how a synthetic DNA vaccine approach successfully protected against infection, brain damage and death caused by the mosquito-borne Zika virus in vivo. More


Creating a Functional Cure for HIV
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The addition of adjuvants to vaccines to stimulate the immune system toward the antigen being injected is a common practice of vaccine delivery. However, trying to awaken the reservoir of dormant viruses in combination with vaccine administration represents a novel approach for human immunodeficiency virus research. Yet, that is precisely the path a team of researchers from Beth Israel Deaconess Medical Center, Walter Reed Army Institute of Research, Janssen Vaccines & Prevention B.V. and Gilead Sciences has taken. More




Career


Open Rank Tenure Track Biomedical Engineering Faculty
Bucknell University
US – PA – Lewisburg

Postdoctoral Research Fellow Neuroscience Early Discovery
Merck
US – MA – Boston

Assistant Professor, Teaching Stream – Neuroscience
University of Toronto
CA – ON – Toronto

Search Jobs at SLAS Career Connections


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