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On-demand scientific presentations: Available 365/24/7 from the convenience of your home or office via your PC, laptop or tablet.
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SLAS2016 Scientific Session Sneak Peek
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Use the SLAS2016 Event Scheduler to plan your personal agenda. Prioritize your choices from more than 130 scientific podium presentations, such as "Droplet Microfluidics: Amphiphilic Nanoparticles as Droplet Stabilizers for High-Fidelity and Ultrahigh-Throughput Droplet Assays" by Sindy K.Y. Tang, Stanford University (Stanford, CA).
Droplet microfluidics, in which nanoliter- to picoliter-sized drops are used to encapsulate and compartmentalize molecules or cells, has enabled a wide range of biochemical applications. Examples include digital PCR and directed evolution of enzymes. The first part of Tang’s SLAS2016 presentation will focus on the design and synthesis of amphiphilic silica nanoparticles for the stabilization of aqueous drops in fluorinated oils for applications in droplet microfluidics. The second part will describe a high-throughput optofluidic droplet interrogation device capable of counting fluorescent drops at a throughput of 254,000 drops per second.
Tang presents at SLAS2016 on Monday, Jan. 25, at 10:30 a.m.
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Prepare for 2016: Renew your SLAS Membership
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To ensure uninterrupted access to all SLAS member benefits, be sure to renew your membership before Dec. 31. Benefits include event registration discounts and year-round educational resources tailored to help you leverage the power of scientific innovation. If you plan to attend SLAS2016, your dues must be paid to be eligible for deep registration discounts. (For your convenience, you can cover your member dues during the SLAS2016 registration process.)
Not able to attend SLAS2016? Membership still pays with on-demand webinars and recorded conference presentations, full access to 23,000+ pages of peer-reviewed science via the MEDLINE-indexed SLAS scientific journals and access to the annual North American Survey of Laboratory Purchasing Trends.
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SLAS and Spanish Drug Discovery Network Explore New Solutions for Drug Discovery
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Target validation, chemical biology, translational research, and new cellular models and technologies were among the topics explored by 120 participants in Barcelona last week during this two-day SLAS event held in collaboration with the Spanish Drug Discovery Network.
"We accomplished our goal of providing a high-value forum for those working in drug discovery in academia, biotech and pharma to discuss the latest solutions-based approaches to move their work forward," says Jordi Quintana, meeting chair and head of the Drug Discovery Platform at the Barcelona Science Park. View photos.
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New App Note! Agilent AssayMAP Sample Prep Platform Enables Reproducible Automated Phosphopeptide Enrichment.
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Win a $500 Amazon Gift Card: Enter the JALA & JBS Art of Science Contest
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Visualization plays an important role in the presentation of scientific work, and often scientific images create mesmerizing shapes, patterns and designs that capture attention and imagination. These are the images JALA and JBS seek for the 2016 Art of Science Contest.
Ten finalists will receive 60 days free online access to the SAGE Pharmacology and Biomedical Collection, and one grand prize winner will receive a $500 Amazon gift card. Entries are due Jan. 4, 2016. Image credit: George Hanson, Life Technologies, Eugene, OR.
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SLAS2016 Registration Discounts End Dec. 18
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Register for SLAS2016 before Friday, Dec. 18 and save up to $200. Additional discounts are available for SLAS members, academic/government professionals, students and organizations that register five or more employees at the same time.
You can renew your SLAS membership (or join the Society!) via the SLAS2016 registration process.
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Free JALA and JBS E-Alerts Deliver the Info that Matters Most to You
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Be the first to know when new scientific reports publish ahead-of-print and when new issues of JALA and JBS become available by signing up for free e-mail alerts at JALA Online and JBS Online. Sign up for keyword alerts to be the first to know when new material about a particular topic becomes available. Plus, authors whose work has been published in JALA and JBS can sign up for citation tracking alerts. All for FREE! More JALA /
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The fully automated Fragment Analyzer is transforming sample analysis in lab, for applications such as DNA, total RNA, gDNA and SSRs. Rapidly and simultaneously qualify and quantify nucleic acid samples in just one step. Choose the kit that meets your parameters, walk away, and resolve fragments in minutes—even if you run a thousand samples a day.
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The BioNex Advantage:
The BNX 1536 Liquid Handling System provides both precise dispensing and thorough microplate washing in a single self-contained instrument. Four independent dispense channels allow reagents to be added without risk of cross-contamination. Configurable for 96–1536 well plates with a dispense range of 500nl to 500ul.
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Scientists Find Surprising Trait in Anti-HIV Antibodies
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Scientists at The Scripps Research Institute have new weapons in the fight against HIV.
Their new study, published as the cover article of the November issue of Immunity, describes four prototype antibodies that target a specific weak spot on the virus. Guided by these antibodies, the researchers then mimicked the molecular structure of a protein on HIV when designing their own potential HIV vaccine candidate.
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Bacterial Molecules Transformed into Novel Potential Drugs
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Scientists at Syracuse University say they have created molecules that mimic and dominate toxic ones secreted by bacteria. They believe that these molecules might be turned into potential drugs.
"Using toxic molecules to develop therapeutic agents, such as a vaccine, is not easy," explains Yan-Yeung Luk, Ph.D., associate professor of chemistry "We're just beginning to understand how some molecules, synthetic or naturally occurring, control the activities of bacteria. This will help us develop, among other things, drugs with many different applications."
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Human Exomes Galore
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The ability to sequence a person's entire genome has led many researchers to hunt for the genetic causes of certain diseases. But without a larger set of genomes to compare mutations against, putting these variations into context is difficult. An international group of researchers has banked the full exomes of 60,706 individuals in a database called the Exome Aggregation Consortium.
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Some 3-D-Printed Parts May Leach Toxic Chemicals
Chemical & Engineering News Share
  
The three-dimensional printing craze has attracted hobbyists and researchers alike, making it easy to fabricate stuff from footwear to molecular models. As the technology becomes cheaper and more popular, however, researchers are investigating potential hazards of these products to people and the environment. A new study shows that parts made by a common 3-D printing method are toxic to zebrafish, a model organism often used to predict toxicological effects on humans.
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3-D Mapping a New Drug-Delivery Tool
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Cubosomes are small biological "capsules" that can deliver molecules of nutrients or drugs with high efficiency. They have a highly symmetrical interior made of tiny cubes of assembled fat molecules similar to the ones in cell membranes. This also means that cubosomes are safe to use in living organisms. Such features have triggered great interest in the pharmaceutical and food industry, who seek to exploit the structure of cubosomes for the controlled release of molecules, improving the delivery of nutrients and drugs.
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Crack-Photolithography for Membrane-Free Diffusion-Based Micro/Nanofluidic Devices
Analytical Chemistry Share
  
Recent advances in controlling the cracking phenomena established a novel unconventional fabrication technique to generate mixed-scale patterns/structures with resolution and accuracy comparable to conventional nanofabrication techniques. Here, we adapt our previous cracking-assisted nanofabrication technique (called "crack-photolithography") relying on only the standard photolithography to develop micro/nanofluidic devices with greatly reduced time and cost.
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Keeping Cool Under Pressure
Lab Manager Share
  
Recently the Safety Guys were asked to help evaluate a stem cell laboratory for possible safety concerns. Though calling it a lab may be a stretch. It was a converted storage room, now housing about a dozen ultra-low temperature freezers and a half dozen large dewars that contained liquid nitrogen used to fill the freezers. As you might imagine, cryopreservation is fraught with dangers and serious potential hazards.
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Primordial Goo Used to Improve Implants
Science Daily Share
  
Australia's national science research organization, CSIRO, has developed an innovative new coating that could be used to improve medical devices and implants, thanks to a "goo" thought to be have been home to the building blocks of life.
The molecules from this primordial goo — known as prebiotic compounds — can be traced back billions of years and have been studied intensively since their discovery several decades ago.
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The comPOUND system comprises a high-density sample storage unit and an additional suite of specialized delivery and processing modules to enable easy integration into any compound management or screening system.
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SLAS Point-to-Point
Colby Horton, Vice President of Publishing, 469.420.2601 Download media kit
Dennis Hall, Executive Editor, 469.420.2656 Contribute news
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