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SLAS
Take a little wonder and the desire to do good. Throw in meaningful research experience, honest commitment, science smarts and a whole lot of energy, and you've taken one step toward describing SLAS's Scientific Director Michael (Mike) Tarselli, Ph.D. The Boston (MA, USA) native started his position with the Society in September and finds his new role yet another way to make life better for scientists, engineers and the world. "In my career, I've worked in start-ups, academia, large pharma and biotechs," says Tarselli in a new article that appears in the SLAS Electronic Laboratory Neighborhood (SLAS ELN). "At SLAS, I saw an opportunity to contribute in yet another way."
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SLAS
Register today for SLAS2019 and browse the Event Scheduler regularly as we continue to add events every day! The podium presentations capture the spectrum of life sciences discovery and technology innovations. Learn the latest from the world of IoT, AI-based analysis and robotics that integrate and provide a unified interface for the heterogeneous world of biological research. Delve into the critical role nanotechnology can play in abnormal scar therapy and diagnostic development. Examine how the disruptive development of new technologies, such as open-source automation technology, IoT and 3D printing, offer endless possibilities for in-house engineering of new laboratory devices, which are compact, adaptable and smart. Discover "cancer-on-a-chip" model systems that could impact the fundamental understanding of how cancer manipulates bone marrow at a new level of spatiotemporal control, and also be used to assess efficacy and toxicity of existing and new anti-cancer drug candidates. To date, the SLAS2019 conference and exhibition offers more than 144 podium presentations, 22 SLAS Short Courses and 281 exhibitors.
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SLAS
Outside, a cold and rainy, overcast Boston — but inside, an intellectual, energetic group traded tales of containers and compliance. The inaugural 2018 SLAS Americas Sample Management Symposium at the Omni Parker House hotel was a warm spot for more than 160 brave attendees from 11 countries and nearly 20 vendors. Symposium Chair Sue Holland-Crimmin, Ph.D., and SLAS CEO Vicki Loise opened a packed room. Keynote speaker Tyler Mulvihill (ConsenSys / Viant.io) challenged the audience to think about blockchain disrupting the space: "someday, every object in this room — or in your lab — will have its whole history and value available to anyone."
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SLAS
SLAS Technology is seeking manuscript proposals (abstracts) for publication in a 2020 special issue. Guest Editors Parastoo Azadi, Ph.D., and Christian Heiss, Ph.D., of the Complex Carbohydrate Research Center at the University of Georgia (Athens, GA, USA), invite manuscript proposals (abstracts) on topics that relate to new developments in carbohydrate structure analysis as well as applications of carbohydrate characterization. A few areas of interest include but are not limited to: mass spectrometry of oligosaccharides or glycoconjugates, NMR techniques for carbohydrate structure analysis, and higher order structures. Manuscript proposals (abstracts) are due May 1, 2019. Invited submissions will be due Aug. 10, 2019. (SLAS Technology is formerly known as the Journal of Laboratory Automation.)
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SLAS
Expand the opportunities for your studies — apply for one of two 2019 SLAS Grants by Monday, Dec. 17! SLAS is accepting applications for:
- SLAS Graduate Education Fellowship Grant — a $100,000 award (up to $50,000 per year, for a maximum of two years) that fosters educational opportunities for outstanding students pursuing graduate degrees related to quantitative biosciences and/or life sciences research.
- SLAS Visiting Graduate Researcher Program — a stipend for a North American or European degree-seeking graduate student to cover a maximum of six months of expenses for mentored or independent research at a different host institution.
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Anton Paar’s Modular Sample Processor allows pipetting, sampling, dosing and weighing to be automated. Available as a benchtop unit or a complete solution integration. MORE
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SLAS
The 2019 SLAS Europe Scientific Program Committee will soon be accepting abstract submissions for the 2019 SLAS Europe Conference and Exhibition, June 26-28, 2019, (Barcelona, Spain). Start assembling your abstract today. Research scientists, engineers, academics and business leaders are encouraged, and graduate students, post-doctoral associates and junior faculty are invited to submit podium presentation abstracts for three educational tracks:
- Advances in In Silico Drug Discovery (covering molecular modeling, data science, analytics and informatics, and advances in methodology)
- Advances in Experimental Drug Discovery (focusing on screening in disease relevant models, new approaches in target discovery and advances in biophysical and bioanalytical technologies)
- Advances in Laboratory Automation Technology (with emphasis on the rise of mass spectroscopy in early drug discovery, next generation high-content bioimaging – phenotypic discovery, and automation and high-throughput technologies)
Students: Apply for an SLAS Tony B. Academic Travel Award when you submit your podium abstract. The deadline for podium presentation abstracts and travel award applications is Feb. 18, 2019.
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SLAS
Video abstracts are a compelling way to boost awareness, readership and citations of your published life sciences research and require relatively little effort or technical expertise to accomplish. SLAS authors today can have a tremendous impact on how their published papers are discovered, recognized and used throughout the scientific community. Learn how with these instructions and helpful hints.
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Journal of the American Chemical Society
Water-mediated interactions play key roles in drug binding. In protein sites with sparse polar functionality, a small-molecule approach is often viewed as insufficient to achieve high affinity and specificity. Here researchers show that small molecules can enable potent inhibition by targeting key waters. The M2 proton channel of influenza A is the target of the antiviral drugs amantadine and rimantadine.
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Science Daily
If pharmaceutical chemists are the drug hunters who discover new medicines, scientists like Andrew McNally and Robert Paton are the armorers — the deft creators who arm drug hunters with the sharpest tools.
The pair of Colorado State University organic chemists have forged a powerful new such tool for drug hunters — a simple, elegantly designed chemical reaction that could fling open an underexplored wing of biologically relevant chemistry.
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Laboratory Equipment
New research reveals how a single protein interferes with the immune system when exposed to the bacterium that causes Legionnaires' disease, findings that could have broad implications for development of medicines to fight disease and infection. "Our immune system protects us from deadly infections, but successful pathogens have evolved many effective ways to subvert its function," said Zhao-Qing Luo, a Purdue University professor of biological sciences.
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Science Daily
An antibiotic called thanatin attacks the way the outer membrane of Gram-negative bacteria is built. Researchers at the University of Zurich have now found that this happens through a previously unknown mechanism. Thanatin, produced naturally by the spined soldier bug, can therefore be used to develop new classes of antibiotics.
The global emergence of multi-drug resistant bacteria is posing a growing threat to human health and medicine.
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Chemical & Engineering News
Carbon and hydrogen make stable bonds that are ubiquitous in organic molecules. That's why chemists spend so much energy looking for ways to break them and replace hydrogens with more useful moieties. One group recently found a new way to make a carbon atom release a hydrogen and accept new substituents. But they didn't understand why the intramolecular reshuffling worked as well as it did with relatively weak oxidants.
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The Scientist
Nanoparticles of indium phosphide — a semiconducting material used in solar cells — installed onto the surface of Saccharomyces cerevisiae allows the yeast to use light to fuel biosynthetic pathways, according to a report in Science. In proof-of-principal experiments, the researchers ramped up the production of shikimic acid, a precursor important for the synthesis of numerous drugs and chemicals.
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Genetic Engineering & Biotechnology News
Named after the two-faced god, newly developed Janus nucleic acid recognition elements target double-stranded DNA or RNA by engaging both strands at once. When strung together within a single-stranded protein nucleic acid, a synthetic construct, Janus elements may bind to natural targets in a sequence-specific manner. What's more, Janus elements, like Janus himself, look backward and forward at the same time.
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Lab Manager
Scientists hoping to develop better treatments for kidney disease have turned their attention to growing clusters of kidney cells in the lab. One day, so-called organoids — grown from human stem cells — may help repair damaged kidneys in people or be used to test drugs developed to fight kidney disease.
But new research from Washington University School of Medicine in St. Louis has identified rogue cells — namely brain and muscle cells — lurking within kidney organoids.
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Job Seekers: Post your résumé and sign up for new job alerts by keyword.
Employers: Search résumés, post an open position, internship or post-doc opportunity. SLAS Premier and Corporate Members get a discount on all new job postings.
Automation Scientist/Engineer for NIST Engineering Biology Program
National Institute of Standards and Technology (NIST)
US – MD – Gaithersburg
Assistant Clinical Investigators, NIAID Transition Program in Clinical Research
National Institute of Allergy and Infectious Diseases (NIAID) / National Institutes of Health
US – MD – Bethesda
SLAS Program Manager
Join the SLAS Professional Team
US – IL – Oak Brook
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