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Certified UPS’s to protect your laboratory’s critical instrumentation and resolve current and potential power issues.
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See how the Thermo Scientific Versette automated liquid handler can meet your liquid handling needs!
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A collaborative compilation of the world's laboratory technology knowledge grown and updated by an online community.
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Vote in the 2014 JALA & JBS Art of Science Contest
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VOTE NOW for your favorite finalist in the 2014 JALA & JBS Art of Science Contest. Share this link with all who appreciate the artistic value of scientific images to captivate and communicate. Online voting, open through Jan. 31, will determine the grand prize winner of a $500 Amazon gift card. SLAS members and nonmembers are invited to vote.
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 Dec. 5: Third phenotypic drug discovery SLAS Webinar
SLAS Share
Mark your calendar for the SLAS Webinar, "Modern Phenotypic Drug Discovery is a Viable Pharma Strategy" presented by Jonathan Lee, Ph.D., of Eli Lilly and Company. Lee is chair of the SLAS PDD Special Interest Group and co-guest editor of the December 2013 and January 2014 two-part special issue of JBS on phenotypic drug discovery; part one of the special issue is now online and available to SLAS Biomolecular Sciences Section members and JBS subscribers. The two previous webinars in the series, featuring David Swinney and Ellen L. Berg, are available on demand. Read more about the three leaders, their work and SLAS Webinar content in the SLAS Electronic Laboratory Neighborhood e-zine.
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SLAS ELN Reports: Olufemi Adeluyi: A Doctor of Technology
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"I advise others to believe in themselves and not be intimidated by challenges," says Olufemi Adeluyi, Chosun University, Gwangju, South Korea. "They should be prepared to work hard and be courageous enough to keep going when they do not succeed on the first try. Never balk regardless of the challenge; rather think big, but start small and scale fast!" Read more about this SLAS member and 2013 Tony B. Academic Travel Award recipient in the SLAS Electronic Laboratory Neighborhood e-zine.
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 JALA podcast on circulating tumor cell enrichment
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Ramdane A. Harouaka, Merisa Nisic and Si-Yang Zheng of Pennsylvania State University talk with JALA Podcast David Pechter about metastatic dissemination and spread of malignant circulating tumor cells (CTCs) and how physical enrichment technologies may enable analysis of rare CTC phenotypes that may not be otherwise obtained. The manuscript is featured on the cover of JALA 18.6 December 2013, part one of the two-part JALA Special Issue on Advancements in Biomedical Micro/Nano Tools and Technology.
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Let Multispan be your one-stop shop partner from cell line and
assay development to screening, lead optimization and
profiling - reduce your cycle time to IND.
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Life Chemicals specializes in organic synthesis for Drug Discovery. We provide compound libraries for HTS, collections of fragments, targeted libraries, building blocks and custom synthesis services.
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 Many SLAS2014 exhibitors to unveil new products in San Diego
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The SLAS Annual Conference and Exhibition is well known as THE place for new product launches and SLAS2014 will not be an exception. A growing list of exhibitors announcing new products and product descriptions is now available online; bookmark this webpage and check back often as the list continues to build.
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Weigh the substance AND the solvent using Quantos automated dispensing systems from METTLER TOLEDO. Preparing accurate concentrations using gravimetric dosing complies with the latest USP guidelines <841>. It offers the benefits of improved quality of results; enhanced user safety; guaranteed process security; and minimized substance and solvent consumption.
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The xCELLigence RTCA-DP System monitors cell migration/invasion using a noninvasive label-free impedance-based technology. This walk-away system allows you to measure cell invasion and migration continuously in real time over the entire time course of an experiment. Visit us at www.aceabio.com.
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Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.
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 Thank you SLAS community!
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As the United States celebrates the Thanksgiving holiday tomorrow in recognition of the Pilgrims who settled the country nearly 400 years ago, the SLAS professional team extends its thanks to you for the commitment you bring to laboratory science and technology. May the good things in life be yours in abundance not only at Thanksgiving, but also throughout the year.
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Researchers gain fuller picture of cell protein reactions
Phys.org Share
Over the past decade, advances in genetic mapping tools have provided great insight into how DNA influences cell behavior. But genetics is only half the equation; much of cells' behavior is the result of post-transcriptional processes, events that occur after DNA is transcribed, carried out by complex enzyme interactions within the cell. The roles that enzymes play in regulating cell behavior have been incompletely understood, largely because researchers have lacked the proper tools to measure the many simultaneous reactions in a cell.
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FDA tells 23andMe to halt sales of genetic test
Bioscience Technology Share
The Food and Drug Administration has ordered Google-backed genetic test maker 23andMe to halt sales of its personalized DNA test kits, saying the company has failed to show that the technology is supported by science. In a warning letter posted online, FDA regulators say that the Silicon Valley company has not shown that its tests are safe or effective despite "more than 14 face-to-face and teleconference meetings" and "hundreds of email exchanges."
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Steering electrons along chemical bonds
Science Daily Share
Electron motions induced by a strong electric field are mapped in space and time with the help of femtosecond x-ray pulses. An x-ray movie of the crystal lithium hydride shows that the electric interaction between electrons has a decisive influence on the direction in which they move. An ionic crystal is a regular arrangement of positively and negatively charged ions in space. A prototype material is the rock salt crystal sodium chloride with elementary units in form of a cube.
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Automated CE-SDS sample preparation webinar
Beckman Coulter Share
Learn the major challenges of CE-SDS sample preparation and when to consider automated sample preparation vs. manual sample preparation with real life data and examples. The speaker, a chemist from Eli Lilly and Company, will also share proven strategies to achieve reproducible peak areas and migration times, minimize user-to-user sample preparation variability and improve workflow efficiency through automated sample preparation. This is a free, on-demand webcast.
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Scigilian is a software company specializing in offering solutions to the problems encountered in pharmaceutical research, biotechnology, and contract research. Trusted, from large pharma to small CRO.
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ASGH workshop now available online
Oxford Gene Technology Share
The recent American Society of Human Genetics workshop, "Complementing next generation sequencing experiments with high-resolution copy number variation detection," discusses the need for comprehensive genomic analysis. It features Professor Madhuri Hegde, professor of human genetics at Emory University School of Medicine and Oxford Gene Technology Chief Executive Dr. Mike Evans. The video is free.
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Momentum builds for Obama's brain initiative
Live Science Share
A new initiative to understand the human brain, announced by President Barack Obama earlier this year, has left people wondering exactly what its goals will be. The project's leaders provided some answers and a healthy dose of enthusiasm at the Society for Neuroscience meeting Nov. 9-13. The BRAIN Initiative (short for Brain Research through Advancing Innovative Neurotechnologies) is a collaborative effort between government agencies and private funding organizations.
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Novel oral anticoagulants for thromboembolic disease
By Dr. Afsaneh Motamed-Khorasani Share
 Vitamin K antagonists are commonly used for the treatment of thromboembolic disease. However, the slow onset of action for these medications limits their use. Therefore, a bridging therapy with the use of low molecular weight heparin, or LMWH is advantageous for the treatment. LMWH has a reduced rate of adverse effects and has replaced the use of heparin. Since heparin and LMWH are parenteral drugs, continuous attempts have been made for alternative oral drugs, and many oral anticoagulants are in phase 3 clinical trials.
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Detecting molecules through bone
Chemical & Engineering News Share
To understand the brain and its chemical complexities, researchers would like to peer inside the skull and observe neurotransmitters at work. Unfortunately, research methods to measure levels of certain chemicals in the brain require drilling holes in the skull. Some neuroscientists have started to develop ways to use magnetic resonance imaging to monitor specific molecules. Now, as a first step toward another noninvasive imaging tool, researchers have shown that they can use Raman spectroscopy to detect chemical signatures through bone.
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Gut bacteria may help combat cancer
New Scientist Share
The friendly bacteria in our gut may help fight cancer. Two new studies in mice show that some anti-cancer therapies work best when the microbes in our body are strong and healthy — which suggests that antibiotics and cancer might not always make a good combination. We know that friendly, or commensal, bacteria can influence inflammation in the body, and that some forms of inflammation help cancers to grow — but it is unclear whether commensal bacteria have a direct influence on cancer development.
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Growth factors for cell culture
Genetic Engineering & Biotechnology News Share
The focus of this GEN Market & Tech Analysis Report is to present the market segmentation and quantitative landscape for growth factors as they are currently utilized for cell culture in various application spaces. We've characterized the marketplace based on telephone interviews as surveys of researchers around the world, and based on this bottom-up analysis we've identified the top growth factors that are currently utilized in the research environment.
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BMG LABTECH is releasing its newest instrument, the CLARIOstar, a high performance microplate reader with advanced monochromators, spectrometer, and filters. With this cutting-edge, hybrid technology, the CLARIOstar offers clear superiority with unparalleled flexibility and sensitivity.
Anything is possible with BMG LABTECH’s CLARIOstar. Any wavelength. Any bandwidth. Any assay.
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Introducing AusWasher MTP, a plate washer with residual volume < 0.01µl, enabling the highest specificity ELISA in 96, 384,1536 well plates with dramatically reduced number of wash steps. Centrifugation eliminates aspiration of wash buffer: no clogging, uniform buffer removal, no damage from physical contact with needles. Available standalone and OEM.
Info: Wolfgang Mann wmann@ausbio.de
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The Prestwick Chemical Library moves into its 14th year of leading the industry with its collection of 1,280 approved drugs available in multiple formats. Applications range from assay development and calibration to single substance and combination screens. Prestwick also provides follow-up chemistry services for lead discovery and optimization.
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SLAS Point-to-Point
Colby Horton, Vice President of Publishing, 469.420.2601
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Dennis Hall, Senior Content Editor, 469.420.2656
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