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SLAS ELN Reports: Power and Potential — MALDI Mass Spec at 30
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The December 2017 SLAS Discovery Special Issue on Advances in MALDI Mass Spectrometry within Drug Discovery captures examples of diverse and exciting advances that inform life sciences researchers about the expanding range of applications of matrix assisted laser desorption/ionization time of flight (MALDI TOF) technology. The issue marks the 30th anniversary of MALDI TOF at a time when "the technology has gained momentum and researchers are recognizing MALDI and applying the technology in innovative ways," says Co-Guest Editor Michael Scholle of SAMDI Tech.
Read more about what's happening with this exciting technology in the SLAS Electronic Laboratory Neighborhood e-zine.
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8 Companies Earn Spots on SLAS Innovation AveNEW at SLAS2018
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With judging criteria that considered technology impact, commercial viability and laboratory automation and technology potential, these start-up companies are featured on Innovation AveNEW at SLAS2018:
Automation Trainer LLC
Benchling
Cell X Technologies
Censo Biotechnologies
The Genomic Automation Company
iota Sciences
VasculoTox, Inc.
Visikol, Inc.
Through this program, SLAS provides entrepreneurs with tremendous exposure and prestige by way of exhibit space and promotional support for their participation at the SLAS Annual Conference and Exhibition.
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NEW SLAS Technology Podcast: Emerging Microtechnologies and Automated Systems for Rapid Bacterial Identification and Antibiotic Susceptibility Testing
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Listen to author Weian Zhao of the University of California, Irvine, as he talks about his new review article, which summarizes and analyzes representative emerging micro- and nanotechnologies and automated systems for bacterial ID/AST, including phenotypic and molecular methods; discusses representative point-of-care systems that integrate sample processing, fluid handling, and detection for rapid bacterial ID/AST; and highlights major challenges and potential future endeavors toward improving clinical outcomes.
Zhao's report is featured in the December 2017 issue of SLAS Technology, and is available for free for a limited time. The full issue is online for SLAS Premier Members, SLAS Technology subscribers and pay-per-view readers.
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New Products to Debut at SLAS2018
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Keep your browser pointed to the SLAS2018 New Products Announcements page for the ever-expanding list of new life sciences breakthrough technologies to be unveiled at the SLAS2018 Exhibition! For example, Axion BioSystems debuts the Maestro Pro Maestro Edge advanced microelectrode array (MEA) systems; IMI Precision Engineering offers the Cadent 3 Syringe Pump; and Visikol Inc. presents its HISTO-M tissue clearing technique. SLAS2018 exhibitors — will you be launching a new product at SLAS2018?
Click here to add your product to the list!
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Groups that rely on Excel files to manage scientific data and communicate results run the risk of operating inefficiently, and their scientific innovation and new development candidates frequently suffer. With this free report, learn how viDA Therapeutics streamlined their processes and improved collaboration.
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NEW at SLAS2018! Solutions Spotlight Presentations
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Quick 20-minute exhibitor presentations are slated for the new SLAS2018 Exhibition Theater in San Diego. A dozen are scheduled to date with many more expected. Once finalized, presentation details can be found in the SLAS2018 Event Scheduler (access the Event Scheduler; browse by Event Type; enter Solutions Spotlight).
SLAS2018 participants should find these informative presentations a nice educational addition to their time spent in the Exhibition.
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Upcoming SLAS Dates and Deadlines
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Mark your calendar today!
Dec. 1 is the abstract deadline for the 2018 SLAS Europe Compound Management Conference
Dec. 8 is the abstract deadline for the 2018 SLAS Europe Conference and Exhibition
Dec. 11 is the application deadline for the $100,000 SLAS Graduate Education Fellowship Grant
Dec. 12 is the SLAS Webinar: How AstraZeneca is Revolutionizing Sample Management with Acoustic Tube-Based Technologies (free access to all)
Dec. 18 is the SLAS2018 advance registration deadline offering discounted rates
Dec. 31 is the deadline to cover Premier/Premier Plus Membership dues for 2018 to ensure no interruption in member benefits
Jan. 4, 2018 is the deadline to reserve SLAS2018 hotel rooms at the negotiated SLAS2018 rate
Jan. 22, 2018 is the final due date for all SLAS2018 poster abstracts
Feb. 4, 2018 is the deadline for SLAS2018 New Product Award applications
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CRISPR Harnessed to Turn Bacteria into Microscopic Tape Recorders
Genetic Engineering & Biotechnology News Share
Scientists have harnessed the bacterial CRISPR/Cas immune system to generate miniature living tape recorders that could feasibly be used to diagnose disease, carry out environmental or microbiological sensing, and record changes in body organs or systems such as the gut.
"Such bacteria, swallowed by a patient, might be able to record the changes they experience through the whole digestive tract, yielding an unprecedented view of previously inaccessible phenomena," comments Harris Wang, Ph.D.
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Biology and Chemistry Combine to Generate New Antibiotics
Phys.org Share
Combining the innovations of synthetic biology with biology and chemistry, a team of scientists at the University of Bristol have generated a brand-new platform that will allow the production of desperately needed brand-new antibiotics.
With resistance growing to existing antibiotics, there is a vital and urgent need for the discovery and development of new antibiotics that are cost effective.
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Biological samples don't have to spoil the day for your compound management team. Much of your automation and processes can be applied to biological sample screening, but there are a few things that might trip you up.
Read Titian's blog and see what you can do to avoid common problems.
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Adenosine-Phosphate-Fueled, Temporally Programmed Supramolecular Polymers with Multiple Transient States
Journal of the American Chemical Society Share
Natural systems have been an inspiration to synthetic supramolecular chemistry. Synthetic demonstrations of dissipative biological systems such as actin filaments are a formidable scientific challenge in attaining future life-like materials. Dynamic instability of such structures beckons control of self-organization in the temporal regimes. In this study, we present a fuel-dependent helical assembly of a supramolecular polymer.
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Clinical Implications of Single-Cell Microfluidic Devices for Hematological Disorders
Analytical Chemistry Share
Microfluidic devices have proven to be valuable platforms with which to synthesize micro- and nanomaterials, develop immunological and environmental assays fabricate in vitro models to study biological systems, as well as develop clinical diagnostics. The plethora of techniques for microfluidic device fabrication provides significant customization in the design of the device specific to the application.
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Good Cells Gone Bad
Bioscience Technology Share
A new study from The Scripps Research Institute (TSRI) is the first to show precisely how a process in nerve cells called the S-nitrosylation (SNO) reaction — which can be caused by aging, pesticides and pollution — may contribute to Parkinson's disease.
The leader of the study, TSRI Professor Stuart Lipton, M.D., Ph.D., is now investigating how new pharmaceuticals might counteract this harmful S-nitrosylation reaction.
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New Method Benchmarks Organic Mixed Conductors
Science Daily Share
Within the past five years, Northwestern University's Jonathan Rivnay has noticed a surge in the development of new organic mixed conductors — polymer materials that can transport both electrons and ions. Lighter, more flexible and easier to process than their inorganic counterparts, the carbon-based materials show promise in a broad assortment of applications, ranging from medical devices to energy storage. But with increased productivity and innovation comes a perhaps unforeseen problem.
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Metal-Binding Polymer Continues to Surprise
Chemical & Engineering News Share
The world's oceans contain more than 4 billion tons of uranium, an amount that could supply fuel for nuclear power production for centuries. The trick is how to harvest the metal ions, which occur at a dilute 3.3 ppb in the vast and deep blue sea.
Chemists have long been developing polymeric materials that selectively absorb uranium, gold and other valuable metals from seawater.
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New Catalyst Controls Activation of a Carbon-Hydrogen Bond
Lab Manager Share
Chemists have developed another catalyst that can selectively activate a carbon-hydrogen bond, part of an ongoing strategy to revolutionize the field of organic synthesis and open up new chemical space.
The journal Nature is publishing the work by chemists at Emory University, following on their development of a similar catalyst last year. Both of the catalysts are able to selectively functionalize the unreactive carbon-hydrogen bonds of an alkane without using a directing group, while also maintaining virtually full control of site selectivity and the three-dimensional shape of the molecules produced.
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Faculty Position, Molecular Imaging Program
Stanford University Medical Center
US – CA – Stanford
Postdoctoral Position, Function of Sensory Neurons
Georgia Institute of Technology
US – GA – Atlanta
Clinical Research Coordinator
University of Washington
US – WA – Seattle
Search Jobs at SLAS Career Connections
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SLAS Point-to-Point
Colby Horton, Vice President of Publishing, 469.420.2601
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Dennis Hall, Executive Editor, 469.420.2656
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