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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit Dec. 4, 2013    SLAS2014    Moving? New job? Let SLAS know.    







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SLAS announces finalists for 2014 SLAS Innovation Award
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Nine scientists delivering podium presentations at SLAS2014 are being honored as SLAS Innovation Award finalists, but only one will receive a $10,000 cash prize at the event, Jan. 18-22 in San Diego. The final step in the evaluation process occurs in San Diego as the SLAS Innovation Award judges score each finalist's presentation based on impact on laboratory automation and screening, originality/creativity, quality of science and oral presentation performance. More


The Lab Man's must-see SLAS2014 presentations
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The Lab Man identifies SLAS2014 presentations that have caught his interest for being off the usual path. One SLAS2014 topic even resurrected memories of The Lab Boy's adventures with the Mattel Thingmaker, Plasti-Goop and toy army men. Are you curious? Visit The Lab Man blog and podcast to find out more! More

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Call for abstracts: JBS special issue on Novel Therapeutic Approaches for Neglected Infectious Diseases
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JBS Guest Editors Julio Martin, Ph.D., and Eric Chatelain, Ph.D., invite manuscript proposals by March 10, 2014, for technological and/or strategic approaches undertaken to discover and advance new chemical entities for the treatment of neglected tropical diseases. This may involve novel methods, success stories and lessons learned. SLAS members and nonmembers alike are welcome to submit proposals. More


Reminder: Tomorrow's SLAS Webinar on phenotypic drug discovery
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Jonathan Lee, Ph.D. Eli Lilly and Company, presents "Modern Phenotypic Drug Discovery is a Viable Pharma Strategy" Thursday, Dec. 5, at 11:30 a.m. EST. This is the third in the phenotypic drug discovery SLAS Webinar series. Previous installments by David Swinney and Ellen L. Berg are available on demand. More

Multispan: Your Drug Discovery Partner

Let Multispan be your one-stop shop partner from cell line and assay development to screening, lead optimization and profiling - reduce your cycle time to IND. More>> Email:
Chemistry Services for Drug Discovery
Life Chemicals specializes in organic synthesis for Drug Discovery. We provide compound libraries for HTS, collections of fragments, targeted libraries, building blocks and custom synthesis services.

Membership renewal tip from SLAS Headquarters
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Mary Geismann, SLAS manager of member services, reminds you that if you want to renew your SLAS membership to take advantage of discounted member rates for SLAS2014, start the process on the SLAS2014 registration page to save yourself some time. Through the convenient and secure online form, you can renew and register seamlessly to maximize your SLAS membership value. The same tip applies to those wishing to become new members of SLAS. But act fast — SLAS2014 advance registration discounts end Dec. 9. More

Intelligent Networking at SLAS2014
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The SLAS2014 conference committee members know that facilitating connections is just as important as presenting high-quality education and exhibits. Therefore, SLAS2014 announces that The Field, Jolt'n Joe's and Rockin' Baja will offer 15 percent discounts off food and beverages for SLAS2014 attendees who show their conference badges. These popular spots near the San Diego Convention Center are perfect for continuing the conversations started during conference programs. More

Gravimetric Sample Preparation from METTLER TOLEDO
Weigh the substance AND the solvent using Quantos automated dispensing systems from METTLER TOLEDO. Preparing accurate concentrations using gravimetric dosing complies with the latest USP guidelines <841>. It offers the benefits of improved quality of results; enhanced user safety; guaranteed process security; and minimized substance and solvent consumption. MORE
Real-Time Monitoring Cell Migration/Invasion
The xCELLigence RTCA-DP System monitors cell migration/invasion using a noninvasive label-free impedance-based technology. This walk-away system allows you to measure cell invasion and migration continuously in real time over the entire time course of an experiment. Visit us at
Add-and-Read Plate Reader
Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.


Toward a single-layer 2-dimensional honeycomb supramolecular organic framework in water
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The self-assembly of well-defined 2D supramolecular polymers in solution has been a challenge in supramolecular chemistry. We have designed and synthesized a rigid stacking-forbidden 1,3,5-triphenylbenzene compound that bears three 4,4'-bipyridin-1-ium (BP) units on the peripheral benzene rings. Three hydrophilic bis(2-hydroxyethyl)carbamoyl groups are introduced to the central benzene ring to suppress 1D stacking of the triangular backbone and to ensure solubility in water. More


Colleges with the most Nobel Prize winners
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You probably wouldn't be surprised to hear that Harvard University has more Nobel Prize winners than any other American higher education institution. But you may not have guessed that Yale University has fewer winners than the University of Chicago. Or that New York University has more Nobel laureates than their upstate neighbor Cornell University. Another Ivy League institution, Princeton, only ties with the City University of New York City College with four Nobel winners each. More

Human stem cells converted to functional lung cells    Share    Share on FacebookTwitterShare on LinkedinE-mail article
For the first time, scientists have succeeded in transforming human stem cells into functional lung and airway cells. The advance, reported by Columbia University Medical Center researchers, has significant potential for modeling lung disease, screening drugs, studying human lung development, and, ultimately, generating lung tissue for transplantation. The study was published in the journal Nature Biotechnology. More


Substrate-integrated hollow waveguides: A new level of integration in mid-infrared gas sensing
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new generation of hollow waveguide (HWG) gas cells of unprecedented compact dimensions facilitating low sample volumes suitable for broad- and narrow-band mid-infrared (MIR; 2.5–20 Μm) sensing applications is reported: the substrate-integrated hollow waveguide (iHWG). iHWGs are layered structures providing light guiding channels integrated into a solid-state substrate material, which are competitive if not superior in performance to conventional leaky-mode fiber optic silica HWGs having similar optical pathlengths. More

Dance your Ph.D.: And the winner is ...
Science Mag    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The votes are in, and the top prize for the 2013 "Dance Your Ph.D." contest goes to ... Cedric Tan, a biologist at the University of Oxford in the United Kingdom, who finished his Ph.D. there last year with a thesis titled "Sperm competition between brothers and female choice." His dance interpretation of that research illustrates the chicken mating process using a range of styles, from swing and water ballet — yes, in actual water — to modern jazz and what can only be described as cockfighting. More

Scigilian Software, Inc.
Scigilian is a software company specializing in offering solutions to the problems encountered in pharmaceutical research, biotechnology, and contract research. Trusted, from large pharma to small CRO.
Dualsystems Biotech AG
Dualsystems Biotech is a provider of custom screening services for industry and academia, specializing in yeast two-hybrid, CaptiVate AP/MS-MS and cDNA library construction.

Cannabidiol: Medical miracle or shameful street drug?
By Maria Frisch    Share    Share on FacebookTwitterShare on LinkedinE-mail article
This summer, CNN's chief medical correspondent, Dr. Sanjay Gupta, led the premiere of a one-hour documentary on medical marijuana. This event reignited many discussions on the topic of medical marijuana and shed some light on the changing politics surrounding this drug. Riding on the coattails of that story is the recent announcement that GW Pharmaceuticals received U.S. Food and Drug Administration orphan drug designation for Epidiolex, a drug that touts cannabidiol as its active ingredient. More

Process holds promise for production of synthetic gasoline from carbon dioxide
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A chemical system developed by researchers at the University of Illinois at Chicago can efficiently perform the first step in the process of creating syngas, gasoline and other energy-rich products out of carbon dioxide. A novel "co-catalyst" system using inexpensive, easy to fabricate carbon-based nanofiber materials efficiently converts carbon dioxide to carbon monoxide, a useful starting-material for synthesizing fuels. The findings have been published online in advance of print in the journal Nature Communications. More


Promise for possible HIV cure
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers have used radioimmunotherapy to destroy remaining human immunodeficiency virus-infected cells in the blood samples of patients treated with antiretroviral therapy, offering the promise of a strategy for curing HIV infection. Results of the study were presented at the annual meeting of the Radiological Society of North America. Highly active antiretroviral therapy has transformed the outlook for patients infected with HIV by suppressing the replication of the virus in the body. More

Are Alzheimer's and diabetes the same disease?
NewScientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Having type 2 diabetes may mean you are already on the path to Alzheimer's. This startling claim comes from a study linking the two diseases more intimately than ever before. There is some good news: the same research also offers a way to reverse memory problems associated with diabetes — albeit in rats — which may hint at a new treatment for Alzheimer's. "Perhaps you should use Alzheimer's drugs at the diabetes stage to prevent cognitive impairment in the first place," says Ewan McNay from the University at Albany in New York. More

The pesticide connection
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The rats in a room at the University of Pittsburgh regularly get hit with doses of pesticide. But the researchers in J. Timothy Greenamyre's lab don’t expose the rodents because of an infestation problem. They give the neurotoxin to the animals to learn more about Parkinson's disease. After receiving a low daily dose of the pesticide rotenone for a week or two, rats in Greenamyre's lab begin to lose mobility in ways similar to Parkinson's patients. More

Finding dollars
Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
If you ask a roomful of research scientists to characterize the competitive process for research funding during the last decade or two, several of them will use words like grueling or even ruthless — a few may even call it cutthroat. Now, however, a number of researchers, and in some cases their professional organizations, appear to be openly implying that the United States is cutting its own throat by defunding innovation-sprouting research via a bludgeon known as the sequester, or more properly, the 2011 Budget Control Act. More

BMG LABTECH Introduces The CLARIOstar
BMG LABTECH is releasing its newest instrument, the CLARIOstar, a high performance microplate reader with advanced monochromators, spectrometer, and filters. With this cutting-edge, hybrid technology, the CLARIOstar offers clear superiority with unparalleled flexibility and sensitivity.

Anything is possible with BMG LABTECH’s CLARIOstar. Any wavelength. Any bandwidth. Any assay.
KMC360 Rapid Medical Product Development
Partner with KMC Systems to leverage over 30 years of medical manufacturing and engineering expertise. We specialize in bringing laboratory automation products to market. Visit us at Booth #1140 to learn more about the KMC360 Rapid Product Development Program. Click here to schedule a meeting.
Prestwick Chemical Library 1,280
The Prestwick Chemical Library moves into its 14th year of leading the industry with its collection of 1,280 approved drugs available in multiple formats. Applications range from assay development and calibration to single substance and combination screens. Prestwick also provides follow-up chemistry services for lead discovery and optimization.


Senior Software Engineer/Architect
US – ME – Westbrook

Research Lab Specialist
St. Jude Children's Research Hospital
US – TN – Memphis

Imaging Post-Doctorial Research Scientist
GlaxoSmithKline (GSK)
UK – Stevenage

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