This message contains images. If you don't see images, click here to view. Advertise in this news brief. Advertisement Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit December 09, 2015 SLAS.org    SLAS2016    Moving? New job? Let SLAS know.       Advertisement Advertisement Advertisement Advertisement Advertisement Advertisement   Advertisement The Lab Man in SLAS ELN: Effective Drug Discovery Begins with the Right Assay SLAS    Share    Developing assays properly is the cornerstone for life sciences R&D. Those new to high-throughput screening and lead discovery may struggle to know where to start. They lean on their more experienced colleagues who have learned the intricacies of effective assay development over the years. Practical how-to information from those in the know is one of the most valuable ways to transfer information in science, and SLAS can help. Editors of the NIH Assay Guidance Manual present a highly interactive full-day workshop at SLAS2016. Learn more from The Lab Man in the SLAS Electronic Laboratory Neighborhood e-zine. More Advertisement Poster Abstracts Still Being Accepted for SLAS2016: Deadline Jan. 11 SLAS    Share    There's still time to share your recent achievements on the SLAS2016 global stage, Jan. 23-27, San Diego. The SLAS2016 Program Committee is still accepting poster abstracts for review and consideration from life sciences R&D and technology professionals at all career stages. Poster presenters must be registered SLAS2016 participants. Register by Dec. 18 to take advantage of advance discounts. More Advertisement View 50+ peer reviewed videos for 3D cell culture See how to grow and analyze spheroids in one microplate Get better accuracy and reproducibility from your automation tips Learn how to improve image capture and data quality during HCS Download a comprehensive selection guide for laboratory automation products The Right Kind of Crazy: A True Story of Teamwork, Leadership and High Stakes Innovation SLAS    Share    The SLAS2016 closing session on Wednesday, Jan. 27, at 3:45 p.m., features a keynote presentation by Adam Diedrich Steltzner, Jet Propulsion Laboratory aeronautics engineer and team lead responsible for the thrilling landing of the Curiosity rover on Mars. His team struggled for almost a decade with design challenges and setbacks. How did he keep the team focused and on task? What makes a team gel and enables truly innovative thinking? How do team dynamics drive that process forward or inhibit it? And how can organizational culture create an environment for sustained performance? The challenges Steltzner and his team faced, and the lessons learned from those struggles, offer advice to those striving to improve their leadership of high-performing teams, manage innovation and achieve excellence. More Advertisement ROBOTIC SAMPLE HANDLING SYSTEMS Experience accelerated research and increased throughput with robotic sample loading systems and accessories from Prior Scientific. Select from our automated slide and well plate loaders, LED and metal halide fluorescence illuminators, Piezo Z stages, motorized filter wheels, high speed shutters as well as custom and OEM electromechanical and optical systems. JALA and JBS Special Issue Calls for Papers SLAS    Share    SLAS guest editors are gathering manuscript proposals (abstracts) for four upcoming special issues of JALA and JBS. Share your expertise and recent research via review papers, original research reports or technology briefs on: Cancer Metabolism (JBS manuscript proposals due April 1, 2016) Micro and Nanotechnologies for Quantitative Biology and Medicine (JALA manuscript proposals due April 1, 2016) Personalized and Precision Medicine (JALA manuscript proposals due June 1, 2016) Quantitative Imaging in Life Sciences and Biomedical Research (JALA manuscript proposals due April 1, 2017) Watch the scientific journals page at SLAS.org for additional announcements. More Advertisement Sartorius Stedim Biotech adds testing services for Biopharma to its offering through acquisition of UK-based CRO BioOutsource. Sartoclear Dynamics is a new single-use technology for harvesting animal cell cultures with high cell densities. BIOSTAT® A - Professional Entry-level Solution for Cell Culture and Microbial Fermentation. Spotlight on Emerging Technologies, Best Practices and More SLAS    Share    Exhibitor Tutorials are one more way SLAS2016 delivers unique educational value. Led by experts from SLAS2016 exhibiting companies, these tutorials provide in-depth explorations of product-specific advances in small group, interactive settings. Exhibitor Tutorials are held Monday and Tuesday, Jan. 25 and 26. More Advertisement SIG Meetings Now in SLAS2016 Event Scheduler SLAS    Share    Sixteen SLAS Special Interest Groups are meeting in San Diego during SLAS2016. These 75-minute idea exchanges will bring together professionals who share specific interests and scientific priorities. Search Special Interest Group in the Browse by Track option in the Podium Presentations & Abstracts section of the SLAS2016 Event Scheduler. More JALA and JBS Online Spotlight China SLAS    Share    JALA and JBS deliver peer-reviewed reports about life sciences R&D achievements from around the world, and a new main menu feature at JALA Online and JBS Online spotlights recently published reports from SLAS authors in China. Learn more about Chinese innovations, such as "Development and Implementation of Autoverification Rules for ELISA Results of HBV Serological Markers," "Gold Nanorods Bioconjugates for Intracellular Delivery and Cancer Cell Apoptosis" and more in JALA. JBS features "Emergence of Chinese Drug Discovery Research: Impact of Hit and Lead Identification," "High-Content Functional Screening of AEG-1and AKR1C2 for the Promotion of Metastasis in Liver Cancer" and more. More Advertisement AUTOMATED, REPRODUCIBLE PHOSPHOPEPTIDE ENRICHMENT New App Note! Agilent AssayMAP Sample Prep Platform Enables Reproducible Automated Phosphopeptide Enrichment. Advertisement Welcome to RAD Source Since 1997 Rad Source Technologies has been the expert in providing renewable, non-isotope, ionizing radiation replacements for self-shielded gamma irradiators. Currently, there are over 300 renowned hospital, university, and pharmaceutical research institutions using Rad Source X-ray technology. To find out more about our equipment, select your application and you will find equipment specifications, literature references, white papers, training videos, discussion forums, as well as other helpful info. Advertisement Nanodrop Low-volume Automated Pipetting The BioNex Advantage: Nanodrop Automated Pipettors are the complete high-throughput solution for low-volume, high-precision pipetting from 100nl to 500µl. Aspirate and dispense up to 16 channels with individual volume control. Valve-free fluid path assures long life and easy maintenance. Ideal for PCR template and cocktail additions, DNA normalization and assay miniaturization. Summit Urges Caution But Doesn't Rule Out Future Gene Editing of Human Embryos Chemical & Engineering News    Share    International scientists and bioethicists who debated gene editing at a summit in Washington, D.C., have issued a statement that does not rule out the controversial use of the technology on human eggs, sperm and early-stage embryos. The statement, released Thursday by the organizers of the International Summit on Human Gene Editing, strongly advocates, however, that any clinical use of edited human embryo or germline DNA should move forward only after certain criteria are met. More Nuclear Receptor's Side Pocket Could Cue Up New Drugs Genetic Engineering & Biotechnology News    Share    Drug development is like a game of molecular billiards in which one must sink drugs into receptors. In the case of nuclear receptors, which are targeted by about 13% of all available pharmaceuticals, the game can be particularly challenging. It has been 50 years since an effective means of binding a novel site on a nuclear receptor has been identified. Calling receptor-binding shots in drug development, however, may soon become easier. More Advertisement Breakthrough Imaging Tool Maps Cells' Composition in 3-D Science Daily    Share    A one-of-a-kind instrument built at Colorado State University lets scientists map cellular composition in three dimensions at the nanoscale, allowing researchers to watch how cells respond to new medications at the most minute level ever observed. The new mass-spectral imaging system is the first of its kind in the world, and its applications are just beginning to surface, said Carmen Menoni, a University Distinguished Professor in the Department of Electrical and Computer Engineering. More Eye-on-a-Chip Represents New Way to Do Disease Research Lab Manager    Share    A clump of cells in a Petri dish may have the same DNA as their counterparts in the body, but most of the similarities end there. Testing how they respond to new drugs, toxins or environmental pollutants provides some insight into how cells might behave in the real world, but such tests can't account for a myriad of factors that come along with the rich, three-dimensional environment they naturally exist within. Animal models provide a closer picture, but come with their own anatomical idiosyncrasies and ethical concerns. More Advertisement It's All About Your Data CLICK to see why CDD Vault is the Drug Discovery Informatics platform your Project Team will embrace, allowing you to effortlessly store & mine all data. Advertisement Become a Lab Superhero! The Mantis will revolutionize your workflow for applications including NGS sample prep, qPCR, assay development, and cellular assays. Automation made simple. Australian Scientists Welcome New Government's 'Ideas Boom' Science Magazine    Share    Scientists at Australia's premier science agency are breathing a sigh of relief. After losing $84 million in funding and 1,400 jobs since 2013, the new government will hand the Commonwealth Scientific and Industrial Research Organisation a welcome $166 million. It's part of Prime Minister Malcolm Turnbull's $730 million signature National Innovation and Science Agenda, announced in Canberra, and billed as an "ideas boom." More Engineers Build Biologically Powered Chip Phys.org    Share    Columbia Engineering researchers have, for the first time, harnessed the molecular machinery of living systems to power an integrated circuit from adenosine triphosphate, the energy currency of life. They achieved this by integrating a conventional solid-state complementary metal-oxide-semiconductor integrated circuit with an artificial lipid bilayer membrane containing ATP-powered ion pumps, opening the door to creating entirely new artificial systems that contain both biological and solid-state components. More Ghosts in the Genome The Scientist    Share    In one of the 20th century's most disastrous collisions of political ideology and science, the Russian botanist Trofim Lysenko steered the USSR's agricultural research policies to deemphasize the deterministic concepts of Mendelian inheritance. Instead, Lysenko was committed to the idea that, within the space of a single generation, the environment could alter the phenotype of future generations, an idea that is now often (imprecisely) referred to as "Lamarckian" inheritance. More Discovery Puts Designer Dopamine Neurons Within Reach Bioscience Technology    Share    For decades, the elusive holy grail in Parkinson's disease research has been finding a way to repair faulty dopamine neurons and put them back into patients, where they will start producing dopamine again. Researchers have used fetal material, which is difficult to obtain and of variable quality. Embryonic stem cells represented a tremendous innovation, but making dopamine neurons from stem cells is a long process with a low yield. More Advertisement Quality Assurance in GLP Environments New White Paper from Xybion Corpororation - Download the Key Elements of Quality Assurance in the Good Laboratory Practice (GLP) Environment. This in-depth white paper explores how quality management and GLP can and should work in harmony in your laboratory. Learn key quality assurance principles such as CAPA and how they apply to labs. Click Here to download Advertisement CLARIOstar innovative microplate reader BMG LABTECH’s most innovative microplate reader with advanced LVF Monochromators™. No longer choose performance over flexibility with this powerful and versatile reader. Filter-like performance, continuously adjustable bandwidths and wavelengths, a dedicated AlphaScreen® laser, UV/Vis spectrometer, and more. For all your assay needs. Advertisement Sample Screening from your Compound The comPOUND system comprises a high-density sample storage unit and an additional suite of specialized delivery and processing modules to enable easy integration into any compound management or screening system. Scientist I/II ImmunoGen US – MA – Waltham Account Manager Global Chemistry Merck & Company Inc. US – NJ – Rahway Assistant, Associate or Full Professor: Malleable Nervous System – From Molecule to Circuit to Behavior University of California, Riverside US – CA – Riverside More jobs at SLAS Career Connections   SLAS Point-to-Point Colby Horton, Vice President of Publishing, 469.420.2601 Download media kit Dennis Hall, Executive Editor, 469.420.2656    Contribute news This edition of SLAS Point-to-Point was sent to ##Email##. To unsubscribe from receiving SLAS Point-to-Point, click here. To unsubscribe from all SLAS e-mail communications, please click here. Did someone forward this edition to you? Subscribe here — it's free! SLAS Terms of Use Policy Recent issues Dec. 2, 2015 Nov. 25, 2015 Nov. 18, 2015 Nov. 11, 2015 7701 Las Colinas Ridge, Ste. 800, Irving, TX 75063