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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit December 09, 2015

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The Lab Man in SLAS ELN: Effective Drug Discovery Begins with the Right Assay
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Developing assays properly is the cornerstone for life sciences R&D. Those new to high-throughput screening and lead discovery may struggle to know where to start. They lean on their more experienced colleagues who have learned the intricacies of effective assay development over the years.

Practical how-to information from those in the know is one of the most valuable ways to transfer information in science, and SLAS can help. Editors of the NIH Assay Guidance Manual present a highly interactive full-day workshop at SLAS2016. Learn more from The Lab Man in the SLAS Electronic Laboratory Neighborhood e-zine.
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Poster Abstracts Still Being Accepted for SLAS2016: Deadline Jan. 11
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There's still time to share your recent achievements on the SLAS2016 global stage, Jan. 23-27, San Diego. The SLAS2016 Program Committee is still accepting poster abstracts for review and consideration from life sciences R&D and technology professionals at all career stages.

Poster presenters must be registered SLAS2016 participants. Register by Dec. 18 to take advantage of advance discounts.
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The Right Kind of Crazy: A True Story of Teamwork, Leadership and High Stakes Innovation
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The SLAS2016 closing session on Wednesday, Jan. 27, at 3:45 p.m., features a keynote presentation by Adam Diedrich Steltzner, Jet Propulsion Laboratory aeronautics engineer and team lead responsible for the thrilling landing of the Curiosity rover on Mars. His team struggled for almost a decade with design challenges and setbacks. How did he keep the team focused and on task? What makes a team gel and enables truly innovative thinking? How do team dynamics drive that process forward or inhibit it? And how can organizational culture create an environment for sustained performance?

The challenges Steltzner and his team faced, and the lessons learned from those struggles, offer advice to those striving to improve their leadership of high-performing teams, manage innovation and achieve excellence.
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JALA and JBS Special Issue Calls for Papers
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SLAS guest editors are gathering manuscript proposals (abstracts) for four upcoming special issues of JALA and JBS. Share your expertise and recent research via review papers, original research reports or technology briefs on: Watch the scientific journals page at SLAS.org for additional announcements. More


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Spotlight on Emerging Technologies, Best Practices and More
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Exhibitor Tutorials are one more way SLAS2016 delivers unique educational value. Led by experts from SLAS2016 exhibiting companies, these tutorials provide in-depth explorations of product-specific advances in small group, interactive settings.

Exhibitor Tutorials are held Monday and Tuesday, Jan. 25 and 26.
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SIG Meetings Now in SLAS2016 Event Scheduler
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Sixteen SLAS Special Interest Groups are meeting in San Diego during SLAS2016.

These 75-minute idea exchanges will bring together professionals who share specific interests and scientific priorities.

Search Special Interest Group in the Browse by Track option in the Podium Presentations & Abstracts section of the SLAS2016 Event Scheduler.
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JALA and JBS Online Spotlight China
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JALA and JBS deliver peer-reviewed reports about life sciences R&D achievements from around the world, and a new main menu feature at JALA Online and JBS Online spotlights recently published reports from SLAS authors in China.

Learn more about Chinese innovations, such as "Development and Implementation of Autoverification Rules for ELISA Results of HBV Serological Markers," "Gold Nanorods Bioconjugates for Intracellular Delivery and Cancer Cell Apoptosis" and more in JALA.

JBS features "Emergence of Chinese Drug Discovery Research: Impact of Hit and Lead Identification," "High-Content Functional Screening of AEG-1and AKR1C2 for the Promotion of Metastasis in Liver Cancer" and more.
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Summit Urges Caution But Doesn't Rule Out Future Gene Editing of Human Embryos
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
International scientists and bioethicists who debated gene editing at a summit in Washington, D.C., have issued a statement that does not rule out the controversial use of the technology on human eggs, sperm and early-stage embryos. The statement, released Thursday by the organizers of the International Summit on Human Gene Editing, strongly advocates, however, that any clinical use of edited human embryo or germline DNA should move forward only after certain criteria are met. More


Nuclear Receptor's Side Pocket Could Cue Up New Drugs
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Drug development is like a game of molecular billiards in which one must sink drugs into receptors. In the case of nuclear receptors, which are targeted by about 13% of all available pharmaceuticals, the game can be particularly challenging. It has been 50 years since an effective means of binding a novel site on a nuclear receptor has been identified. Calling receptor-binding shots in drug development, however, may soon become easier. More


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Breakthrough Imaging Tool Maps Cells' Composition in 3-D
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A one-of-a-kind instrument built at Colorado State University lets scientists map cellular composition in three dimensions at the nanoscale, allowing researchers to watch how cells respond to new medications at the most minute level ever observed. The new mass-spectral imaging system is the first of its kind in the world, and its applications are just beginning to surface, said Carmen Menoni, a University Distinguished Professor in the Department of Electrical and Computer Engineering. More


Eye-on-a-Chip Represents New Way to Do Disease Research
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A clump of cells in a Petri dish may have the same DNA as their counterparts in the body, but most of the similarities end there. Testing how they respond to new drugs, toxins or environmental pollutants provides some insight into how cells might behave in the real world, but such tests can't account for a myriad of factors that come along with the rich, three-dimensional environment they naturally exist within. Animal models provide a closer picture, but come with their own anatomical idiosyncrasies and ethical concerns. More


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Australian Scientists Welcome New Government's 'Ideas Boom'
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Scientists at Australia's premier science agency are breathing a sigh of relief. After losing $84 million in funding and 1,400 jobs since 2013, the new government will hand the Commonwealth Scientific and Industrial Research Organisation a welcome $166 million. It's part of Prime Minister Malcolm Turnbull's $730 million signature National Innovation and Science Agenda, announced in Canberra, and billed as an "ideas boom." More


Engineers Build Biologically Powered Chip
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Columbia Engineering researchers have, for the first time, harnessed the molecular machinery of living systems to power an integrated circuit from adenosine triphosphate, the energy currency of life. They achieved this by integrating a conventional solid-state complementary metal-oxide-semiconductor integrated circuit with an artificial lipid bilayer membrane containing ATP-powered ion pumps, opening the door to creating entirely new artificial systems that contain both biological and solid-state components. More




Ghosts in the Genome
The Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In one of the 20th century's most disastrous collisions of political ideology and science, the Russian botanist Trofim Lysenko steered the USSR's agricultural research policies to deemphasize the deterministic concepts of Mendelian inheritance. Instead, Lysenko was committed to the idea that, within the space of a single generation, the environment could alter the phenotype of future generations, an idea that is now often (imprecisely) referred to as "Lamarckian" inheritance. More


Discovery Puts Designer Dopamine Neurons Within Reach
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
For decades, the elusive holy grail in Parkinson's disease research has been finding a way to repair faulty dopamine neurons and put them back into patients, where they will start producing dopamine again. Researchers have used fetal material, which is difficult to obtain and of variable quality. Embryonic stem cells represented a tremendous innovation, but making dopamine neurons from stem cells is a long process with a low yield. More


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Career


Scientist I/II
ImmunoGen
US – MA – Waltham

Account Manager Global Chemistry
Merck & Company Inc.
US – NJ – Rahway

Assistant, Associate or Full Professor: Malleable Nervous System – From Molecule to Circuit to Behavior
University of California, Riverside
US – CA – Riverside

More jobs at SLAS Career Connections


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