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Drive to DC Program for Students and Early Career Professionals
SLAS Share
  
Would you like SLAS to pay for your gas to SLAS2105?
Participate in the SLAS2015 Drive to DC program. The first 30 teams of Students and Early Career Pros to sign up for this new program will have their gas expenses (up to $150) reimbursed. Take and tweet pictures of your SLAS2015 Drive to DC car magnet along the way to #SLAS2015 and #DrivetoDC for a chance to win the Kerouac Prize of $100 cash.
Sign up for Drive to DC program is required by Jan. 23, 2015 — contact Mary Geismann to register for this program and for more details. The Drive to DC program is just one of many perks for young scientists attending SLAS2015. Check the website for registration discounts, career workshops, counseling sessions and networking events with food and drink.
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SLAS ELN Reports: Marc Bickle — A Quest for Cell Culture Relevance
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SLAS member Marc Bickle, Ph.D., is fascinated with cell culture and its link to life sciences. He is also obsessed with data quantification. His interests led him from researching worms to yeast to high-content screening and beyond, now as head of the Technology Development Studio of the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany.
Read more about this SLAS2015 Short Course instructor, JBS Editorial Board member and guest editor of the upcoming JBS special issue, Screening by RNAi and Precise Genome Editing Technologies, in the SLAS Electronic Laboratory Neighborhood e-zine.
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JALA Special Issue Call for Manuscript Proposals: High-Throughput Imaging Technologies
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Guest Editor Michael Kuo, M.D., invites manuscript proposals by April 1.
"Rapid improvements in imaging capabilities, including advances in molecular imaging and radiogenomics, are enabling the non-invasive capture of macroscopic and subcellular features," Kuo states.
"Thus, imaging is no longer a tool of simple detection but is now being used to characterize and quantify disease, predict treatment response and guide and select therapy, provide insights into fundamental biology and identify and localize molecular targets. In this issue, we will highlight and explore diverse imaging approaches and their applications."
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BAMS brings a new paradigm to mass spectrometry by combining bead-based multiplexing and plate-based self-assembly.
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SLAS Online Learning — Growing to Meet Education Needs
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The SLAS Online Learning Center allows SLAS members to experience conference quality professional education from the comfort of home or office. In 2014, the SLAS eLearning Advisory Committee re-engineered its approach to SLAS Webinars, shifting from a series model of three related presentations to individual, single topic-focused presentations. The change was well received and live audience levels increased while the catalog of SLAS Webinars On-Demand grew to nearly 40. Recently added to the recordings list are:
March and April 2015 SLAS Webinar topics and speakers also are on the website.
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Attention JALA & JBS Authors & Reviewers: Update Your Info & Opt-in Today
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Be sure you receive important e-mail announcements by updating your personal profile information in the JALA and JBS SAGEtrack systems. Pay special attention to your "attributes" (areas of expertise) selections and be sure to "OPT-IN," so SLAS can keep you informed of special issues and other publication opportunities.
- JALA SAGEtrack Users: Login, click on your name (top/right of homepage), select User ID & Password from the dropdown menu.
- JBS SAGEtrack Users: Login, click on your name (top/right of homepage), select User ID & Password from the dropdown menu.
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Welcome Genedata — New SLAS Corporate Member
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Headquartered in Switzerland, Genedata transforms data into intelligence with a portfolio of advanced software solutions to make research data accessible and understandable and research processes more efficient. The Genedata Screener captures, visualizes and manages data from high, medium and low-throughput screens performed with a range of technologies on a wide array of instruments, including high-content screening, ion channel screening and label-free screening. The software's screening-oriented business logic enables rapid processing and comprehensive analysis of complete campaigns, regardless of the number of plates or read-outs.
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• Functional, mixed population of atrial, ventricular, nodal cells
• Confirmed utility in identifying therapeutic approaches
• Demonstrated value in targeted and phenotypic screening
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Save time and money with Acquire™ lab supplies management software.
Streamline compound management with Store™
Make internal and external compounds and assays accessible to all project teams with Request™
Visualize™ enables securely sharing compound and biological assay results.
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Cytation™ 3 is a cell imaging multi-mode microplate reader that combines automated digital microscopy and conventional microplate detection. This unique patent pending design provides rich phenotypic cellular information with well-based quantitative data.
Click here to learn more.
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Drug Development in a Time of Ebola
Bioscience Technology Share
  
Forbes kicked off the 2014 Healthcare Summit with this session titled, "Drug Development in A Time of Ebola." Forbes senior editor Matthew Herper interviewed Edward Cox and Lucianna Borio, two high-ranking officials at the U.S. Food and Drug Administration.
Cox leads the Office of Antimicrobial Products along with the Center for Drug Evaluation and Research, while Borio serves as the Assistant Commissioner for Counterterrorism Policy.
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Nanoparticle Cluster Manufacturing Technique Using DNA Binding Protein Developed
Science Daily Share
  
Scientists in South Korea used the Zinc Finger protein to develop a new manufacturing technique for size-controllable magnetic Nanoparticle Clusters. Professor Hak-Sung Kim of the Department of Biological Sciences at Korea Advanced Institute of Science and Technology and Yiseul Ryu, a doctoral candidate, used the Zinc Finger protein that specifically binds to target DNA sequence to develop a new manufacturing technique for size-controllable magnetic Nanoparticle Clusters.
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Single-Cell Analysis Hints at Stem Cell Code Linking Transcription and Development
Genetic Engineering & Biotechnology News Share
  
Exercising unprecedented delicacy, researchers probed the regulatory circuits that govern the transitions between stem cells' pluripotent states. The researchers uncovered far more variation in pluripotent stem cells than was previously appreciated. In addition, they learned that there are many small fluctuations in the state of a stem cell's pluripotency that can influence which developmental path it will follow.
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Chemists Create 'Artificial Chemical Evolution' for First Time
Phys.org Share
  
Scientists have taken an important step towards the possibility of creating synthetic life with the development of a form of artificial evolution in a simple chemistry set without DNA. A team from the University of Glasgow's School of Chemistry report in the journal Nature Communications how they have managed to create an evolving chemical system for the first time. The process uses a robotic "aid" and could be used in the future to "evolve" new chemicals capable of performing specific tasks.
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During SLAS, visit CDD (Booth 1155) to see how you can effortlessly store, analyze, & mine your biological study data & chemical structures with CDD Vault®. Finally, a modern approach to drug research informatics. Click here!
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Scigilian is a software company specializing in offering solutions to the problems encountered in pharmaceutical research, biotechnology, and contract research. Trusted, from large pharma to small CRO.
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Making Chemistry Green
The New York Times Share
  
For nearly 40 years, the Food and Drug Administration has wrestled with regulating the chemicals triclosan and triclocarban as they have become among the world's most ubiquitous environmental contaminants. Designed to kill bacteria, they have been added to antibacterial soaps, cosmetics and other consumer products despite longstanding concerns about their impacts on humans and the environment.
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Unusual Electronic State Found in New Class of Unconventional Superconductors
Lab Manager Share
  
A team of scientists from the U.S. Department of Energy's Brookhaven National Laboratory, Columbia Engineering, Columbia Physics and Kyoto University has discovered an unusual form of electronic order in a new family of unconventional superconductors. The finding, described in the journal Nature Communications, establishes an unexpected connection between this new group of titanium-oxypnictide superconductors and the more familiar cuprates and iron-pnictides.
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Mixed Signals
Chemical & Engineering News Share
  
Within a week of publication of C&EN's 2013 Pharmaceutical Year in Review, a new drug called Sovaldi was introduced. Like others before, it came with a backstory and kicked off a new adventure for the firm that developed it and the patients, physicians and payers that populate the market. In the case of Sovaldi, a highly effective treatment for hepatitis C, the narrative illuminates the key issues and dilemmas characterizing the drug industry in 2014.
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Expanding the Analytical Toolbox: Pharmaceutical Application of Quantitative NMR
Analytical Chemistry Share
  
In response to the changing market pressures being applied to the pharmaceutical industry, a greater emphasis is being made to advance new drugs to market with minimal investment in early development stages. The use of quantitative NMR (q-NMR) has been shown to be a single point replacement for routine early development testing which previously combined elements of identity testing, chromatographic assay, moisture analysis, residual solvent analysis, and elemental analysis.
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6.2 Shipping Training is required biennially – when was the last time you trained?
All training is conducted in accordance with the regulations published by IATA, ICAO, US DOT, Transport Canada, RID/ADR and the Universal Postal Union
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The xCELLigence RTCA Cardio System monitors cardiomyocyte beating functions in a 96-well format under physiological conditions, using a noninvasive label-free impedance-based technology. Rule out both acute and long-term cardiotoxicity in a single experiment. For more information, please visit www.aceabio.com.
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