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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit Dec. 18, 2013    SLAS2014    Moving? New job? Let SLAS know.    







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Chow named JALA Deputy Editor-in-Chief
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SLAS has appointed Edward Kai-Hua Chow, Ph.D., University of Singapore, to the position of Deputy Editor-in-Chief for the Journal of Laboratory Automation (JALA). In his new role, Chow will work closely with JALA Editor-in-Chief Dean Ho, Ph.D., University of California, Los Angeles, throughout 2014 to transition planning initiatives and management responsibilities before assuming full responsibilities as JALA Editor-in-Chief effective Jan. 1, 2015. More


SLAS2014 poster abstracts still being accepted / final deadline is Jan. 6
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There is still time to be considered for a scientific poster presentation at SLAS2014, Jan. 18-22. Submit your abstract by Monday, Jan. 6, to be reviewed by the SLAS2014 Program Committee. Take advantage of this opportunity to showcase your research and gain meaningful insight from your colleagues. View the SLAS2014 Poster Gallery to see posters already selected for presentation in San Diego. More

Sponsored Content

SLAS ELN Reports: Disruptive Technologies Poised to Transform Drug Discovery
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Innovators from Rice University, Promega Corporation, 908 Devices and the Genomics Institute of the Novartis Research Foundation are transforming researchers' efforts to identify new and effective treatments. Their disruptive technologies are streamlining drug discovery by making the process faster and more cost effective without sacrificing quality. Read about their efforts in the SLAS Electronic Laboratory Neighborhood e-zine. More


Maximize learning and minimize travel expenses at SLAS2014
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Past attendees have found that arriving a day or two before the SLAS conference to take a short course is an excellent use of time and financial resources. At SLAS2014, Short Course topics offered are as varied as:
  • Implementing the appropriate laboratory information management system, taught by an analytical chemist with 30-plus years of experience
  • Best practices in sample management — traditional compound management as well as biologics — led by expert practitioners spanning both realms
  • Introduction to microfluidics and application in the life sciences from course leaders who together have 65 years of global work in the field
See the full list of 17 SLAS2014 Short Courses.

Multispan: Your Drug Discovery Partner

Let Multispan be your one-stop shop partner from cell line and assay development to screening, lead optimization and profiling - reduce your cycle time to IND. More>> Email:
Chemistry Services for Drug Discovery
Life Chemicals specializes in organic synthesis for Drug Discovery. We provide compound libraries for HTS, collections of fragments, targeted libraries, building blocks and custom synthesis services.

Call for abstracts: JALA special issue on New Developments in Biosensing Technologies
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JALA Guest Editor Xianting Ding, Ph.D., of Shanghai Jiao Tong University, China, invites manuscript proposals by Aug. 1, 2014. This issue will present novel technologies and systems for the advancement of biosensing in all perspectives of biosystems from cancers, infectious diseases, aging diseases and chronics to surgery requested scenarios. SLAS members and nonmembers alike are welcome to submit proposals. More

Gravimetric Sample Preparation from METTLER TOLEDO
Weigh the substance AND the solvent using Quantos automated dispensing systems from METTLER TOLEDO. Preparing accurate concentrations using gravimetric dosing complies with the latest USP guidelines <841>. It offers the benefits of improved quality of results; enhanced user safety; guaranteed process security; and minimized substance and solvent consumption. MORE
Real-Time Monitoring Cardiomyocyte Beating
The xCELLigence RTCA Cardio System monitors cardiomyocyte beating functions in a 96-well format under physiological conditions, using a noninvasive label-free impedance-based technology. Rule out both acute and long-term cardiotoxicity in a single experiment. For more information, please visit
Add-and-Read Plate Reader
Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.

Reminder: SLAS2014 hotel reservation deadline is tomorrow!
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Thursday, Jan. 19, is the deadline for making reservations at the Hilton San Diego Bayfront and the San Diego Marriott Marquis & Marina at SLAS2014 discount rates. Rates are not guaranteed for rooms reserved after this date. More



Researchers grow kidney from stem cells
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
University of Queensland researchers have made a major leap forward in treating renal disease, announcing they have grown a kidney using stem cells. The breakthrough paves the way for improved treatments for patients with kidney disease and bodes well for the future of the wider field of bioengineering organs. Professor Melissa Little from UQ's Institute for Molecular Bioscience, who led the study, said new treatments for kidney disease were urgently needed. More

Murgocil is a highly bioactive staphylococcal-specific inhibitor of the peptidoglycan glycosyltransferase enzyme MurG
ACS Chemical Biology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Modern medicine is founded on the discovery of penicillin and subsequent small molecules that inhibit bacterial peptidoglycan and cell wall synthesis. However, the discovery of new chemically and mechanistically distinct classes of PG inhibitors has become exceedingly rare, prompting speculation that intracellular enzymes involved in PG precursor synthesis are not "druggable" targets. More


Portable thermo-powered high-throughput visual electrochemiluminescence sensor
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
This paper describes a portable thermo-powered high-throughput visual electrochemiluminescence sensor for the first time. This sensor is composed of a tiny power supply device based on thermal-electrical conversion and a facile prepared array electrode. The ECL detection could be conducted with thermo-power, which is easily accessible. For example, hot water, a bonfire, or a lighted candle enables the detection to be conducted. More

Researchers study evolution on the molecular level    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The theory of evolution suggests that present-day organisms evolved from earlier life forms. At the molecular level, evolution reshaped some of the enzymes that help complete chemical processes — such as converting food into energy — in humans and all other life forms. Now a University of Iowa researcher and his colleagues describe the evolution of various forms of the enzyme "dihydrofolate reductase" as it occurred from bacteria to humans. More

Scigilian Software, Inc.
Scigilian is a software company specializing in offering solutions to the problems encountered in pharmaceutical research, biotechnology, and contract research. Trusted, from large pharma to small CRO.
Dualsystems Biotech AG
Dualsystems Biotech is a provider of custom screening services for industry and academia, specializing in yeast two-hybrid, CaptiVate AP/MS-MS and cDNA library construction.

Nanoparticles loaded with curcumin boost memory in Alzheimer's animal model
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A natural compound found in turmeric has shown promise as a potential treatment for Alzheimer's disease but delivering it to the brain has been a challenge. Now researchers have packaged this compound, curcumin, inside polymer nanoparticles to help it get into the brain. For the first time, they've shown that this encapsulated curcumin can stimulate the production of neurons and improve memory in a rat model of Alzheimer's disease. More

The role of nanomaterials in the treatment of cerebral palsy
By Dr. Afsaneh Motamed-Khorasani    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Although there are different causes for the development of cerebral palsy, neuroinflammation plays a major role in brain injury. At present, there is no effective cure for this disorder. Therefore, a therapeutic approach that targets the brain with minimum side effects, crosses the blood-brain barrier and affects only cells involved in injury would be beneficial. Recently, nanoparticle-based therapeutic approaches have been studied for prevention and treatment of brain injury. Nanomaterials, such as dendrimers, have the benefit of a targeted delivery for multiple drugs, which can interact with several pathways involved in injury. More


Characteristics of cancer stem cells
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The focus of this GEN Market & Tech Analysis report is to frame the challenging space of cancer stem cells. Highlights of this report include: The potential relationship between circulating tumor cells and CSCs is unclear at present — this is important since it underlines the mechanism(s) by which components of the primary tumor migrate to distal sites and induce mets, the drivers for morbidity and mortality in late-stage cancer patients. More

A blood test that predicts suicide?
By Dorothy L. Tengler    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Suicide is the 10th-leading cause of death for Americans. In 2010, someone in the United States died by suicide every 13.7 minutes. Alexander Niculescu, a psychiatrist at Indiana University in Indianapolis, has been looking for biological signs of suicide risk in an effort to prevent these tragedies. Because of the brain's complexity and inaccessibility, he has focused on molecular signs, such as biomarkers. Niculescu and colleagues recently identified six such biomarkers in the blood that may identify people at risk of committing suicide. More

Noble gas molecule discovered in space
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A molecule containing a noble gas has been discovered in space by a team including astronomers from Cardiff University. The find was made using a Cardiff-led instrument aboard Europe's Herschel Space Observatory. The molecule, argon hydride, was seen in the Crab Nebula, the remains of a star that exploded 1,000 years ago. Before the discovery, molecules of this kind have only been studied in laboratories on Earth. More

Diet switch sparks gut bug revolution in just 24 hours
New Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
It takes just 24 hours to change the balance of power in your gut. Switching to a diet based exclusively on animals or plants triggers rapid changes to the microbes that rule your gut. This knowledge could help fine-tune diets to improve health, as well as reduce the risk of illnesses like inflammatory bowel disease. The human body contains a community of other organisms known as a microbiome. These microbial cells outnumber our own by 10 to 1, with most of them colonizing the gut. More

BMG LABTECH Introduces The CLARIOstar
BMG LABTECH is releasing its newest instrument, the CLARIOstar, a high performance microplate reader with advanced monochromators, spectrometer, and filters. With this cutting-edge, hybrid technology, the CLARIOstar offers clear superiority with unparalleled flexibility and sensitivity.

Anything is possible with BMG LABTECH’s CLARIOstar. Any wavelength. Any bandwidth. Any assay.
KMC360 Rapid Medical Product Development
Partner with KMC Systems to leverage over 30 years of medical manufacturing and engineering expertise. We specialize in bringing laboratory automation products to market. Visit us at Booth #1140 to learn more about the KMC360 Rapid Product Development Program. Click here to schedule a meeting.
Prestwick Chemical Library 1,280
The Prestwick Chemical Library moves into its 14th year of leading the industry with its collection of 1,280 approved drugs available in multiple formats. Applications range from assay development and calibration to single substance and combination screens. Prestwick also provides follow-up chemistry services for lead discovery and optimization.


Senior Software Engineer/Architect
US – ME – Westbrook

Assistant Professor Agricultural Engineering Technology
University of Wisconsin-River Falls
US – WI – River Falls

Associate Director – High-Throughput Screening
Vertex Pharmaceuticals, Inc.
US – CA – San Diego

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