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  Mobile version   RSS   Subscribe   Unsubscribe    SLAS2012   Moving? New job? Let SLAS know.    Dec. 21, 2011



SLAS2012 short courses are filling up
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Thinking about taking an SLAS2012 short course Feb. 4 or Feb. 5? Sign up now, as each short course accommodates a limited number of attendees for maximum effectiveness, and many are reaching capacity. More


JALA announces special issue call for papers
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Guest Editors Wen J. Li, Ph.D., and Ning Xi, Ph.D., of City University of Hong Kong, invite submissions on topics exploring robotics for laboratory automation. Abstracts are due Feb. 15, 2012. More

Small automated pipettors perform big
SOLO & SOLOPlus Automated Pipettors are the perfect choice for automating repetitive and time consuming applications. Available in single channel, 8-channel and 12- channel configurations the SOLO handles serial dilutions, kinase assays and next-gen sequencing prep with ease. Multiple deck configurations, accessories and robotics are available. See more at Email

SLAS2012 speaker Peter Schultz's work heralded
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The work of the Peter Schultz laboratory at Scripps Research Institute to insert an unnatural amino acid into proteins made by Escherichia coli by borrowing a synthetase and a tRNA from an archaea microbe is featured in Chemical & Engineering News Chemical Year in Review 2011. More


Humans on a chip?
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"This new NIH DARPA challenge is to combine microfabrication techniques with modern tissue engineering to allow different populations of cells to connect, communicate and form a more complete physiological system that can better mimic the behavior of human organs,” says Dino Di Carlo, Ph.D. Read about it in a new SLAS Electronic Laboratory Neighborhood feature. More

JBS epigenetics special issue released
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The December 2011 issue, Epigenetic-Targeted Drug Discovery, Part I, is now available at JBS Online. Guest editors Tom Heightman, Astex Pharmaceuticals, and Andrew Pope, GlaxoSmithKline, say the issue features contributions from leading public sector, biotech and pharmaceutical groups who are applying 21st century drug discovery techniques to allow the generation and characterization of small molecule inhibitors of epigenetic regulatory proteins. More

Screen Your Compounds at Multispan

In human and ortholog GPCR stable cell lines in Calcium, cAMP, IP-1, GTPγS, ligand-binding and internalization assays, offering the fastest turnaround, highest quality and most diversity. More>>

JALA scientific advisor joins PrimeraDx board
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PrimeraDx appointed Leroy Hood, M.D., Ph.D., of the Institute for Systems Biology and a global leader in the molecular device industry, to its Scientific Advisory Board. More

Thank you, Mark Herrmann!
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SLAS member Mark Herrmann, ARUP Laboratories, provided stunning photography for a recent SLAS Electronic Laboratory Neighborhood feature, "Bridging the Valley of Death: How Can Academia and Pharma Best Work Together?" More
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Introducing the BIND® SCANNER from SRU Biosystems
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MaxCyte Excels in Difficult-to-Transfect Cells

CHO, HEK, Jurkat, insect cells, primary cells…The MaxCyte® STX™ Scalable Transfection System transiently transfects even the most Difficult-to-Transfect Cells with ease! Transfect up to 1E10 cells in less than 30 minutes! The STX produces the quality transfected cells you need for screening and antibody production. Find out more about MaxCyte Transfection.


Cornell wins NYC Tech Campus bid
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New York Mayor Michael R. Bloomberg, Cornell University President David J. Skorton and Technion-Israel Institute of Technology President Peretz Lavie announced an historic partnership to build a two-million-square-foot applied science and engineering campus on Roosevelt Island in New York City. More


Naked mole rats evolved to handle acid
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A new study explains why naked mole rats surprisingly feel no pain from acid. The findings, by scientists at the Max Delbrück Center for Molecular Medicine in Berlin, Germany, may prove useful in tackling human pain. Their results are published in this week's issue of Science. More

NIMBUS Personalized Pipetting Workstation

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US agencies collaborate to test 10,000 chemicals
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A high-speed robotic screening system jointly initiated by three key US health agencies began testing more than 10,000 chemical compounds for potential toxicity on Dec. 7. The National Institutes of Health, the Environmental Protection Agency and the Food and Drug Administration aim to improve how chemicals, including many consumer products, food additives and pharmaceuticals, are tested for safety. More

Track Cell Behavior Kinetically

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A map of minor groove shape and electrostatic potential from hydroxyl radical cleavage patterns of DNA
ACS Chemical Biology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
DNA shape variation and the associated variation in minor groove electrostatic potential are widely exploited by proteins for DNA recognition. Here we show that the hydroxyl radical cleavage pattern is a quantitative measure of DNA backbone solvent accessibility, minor groove width and minor groove electrostatic potential, at single nucleotide resolution. More


SCINOMIX’S SCI-PRINT VX2 is a small footprint multifunction vial handling system. The SCI- PRINT MP2+ is a high throughput fully automated barcode label printer for microtiter plates and deep well blocks. Click here to see product videos and more!

A gene-fusion strategy for stoichiometric and co-localized expression of light-gated membrane proteins
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The precise co-localization and stoichiometric expression of two different light-gated membrane proteins can vastly improve the physiological usefulness of optogenetics for the modulation of cell excitability with light. Here we present a gene-fusion strategy for the stable 1:1 expression of any two microbial rhodopsins in a single polypeptide chain. More


Evolutionary paths to antibiotic resistance under dynamically sustained drug selection
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Antibiotic resistance can evolve through the sequential accumulation of multiple mutations. To study such gradual evolution, we developed a selection device, the "morbidostat," that continuously monitors bacterial growth and dynamically regulates drug concentrations, such that the evolving population is constantly challenged. More

Twist in the tail of eukaryotic origins
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Complex life may have had parasitic origins. New evidence suggests that the relatives of the mitochondria within our cells once had a tail, like many parasitic bacteria. Life on Earth is packaged into three domains: the simple bacteria, the archaea and the complex eukaryotes that make up most of the life we see with the naked eye. More

Corning® Bar Coded Storage Tubes
Corning Bar Coded Storage Tubes are a superior storage solution designed to provide maximum identification with synchronized 2D/linear bar codes and a marking spot on the tube side wall. Both 96 and 384 tube formats feature a 14 x 14 dot, 2D, laser-etched bar code.

Scientists uncover evidence on how drug-resistant tuberculosis cells form
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A new study led by Harvard School of Public researchers provides a novel explanation as to why some tuberculosis cells are inherently more difficult to treat with antibiotics. The discovery, which showed that the ways mycobacteria cells divide and grow determine their susceptibility to treatment with drugs, could lead to new avenues of drug development that better target tuberculosis cells. More

A full work-up for Alzheimer's disease
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Moving a step closer to increasing opportunities to diagnose Alzheimer's disease before memory loss occurs, the Cleveland Clinic's Lou Ruvo Center for Brain Health has been chosen by Paris-based Exonhit SA to conduct the first U.S. pilot clinical trial for AclarusDx, a blood-based investigational diagnostic test. More

Cockroach 'let's hook up' chemical signal could benefit endangered woodpecker
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A North Carolina State University discovery of the unique chemical composition of a cockroach signal — a "Let's hook up" sex pheromone emitted by certain female wood cockroaches to entice potential mates — could have far-ranging benefits, including improved conservation of an endangered woodpecker. More

Phthalazinone pyrazoles as potent, selective, and orally bioavailable inhibitors of Aurora-A kinase
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The inhibition of Aurora kinases in order to arrest mitosis and subsequently inhibit tumor growth via apoptosis of proliferating cells has generated significant discussion within the literature. We report a novel class of Aurora kinase inhibitors based upon a phthalazinone pyrazole scaffold. More

DNA Extraction WorkStation

Thermo Scientific Orbitor KingFisher Flex Extraction Workstation allows users to extract more nucleic acids/proteins in less time. The small, easy-to-use solution provides unattended walk-away time, better control of processes and greater sample consistency combined with an audit trails of all operations performed (time-stamped, stored records). Contact us to learn more.
Douglas Scientific's Soellex™ PCR Thermocycler
The Soellex™ PCR thermocycler is optimized for Array Tape™ to provide ultra high capacity DNA amplification – simultaneously processing up to 230,000 reaction wells in a standard run. The heating system in the Soellex™ tightly controls the temperature throughout the water column delivering efficient and rapid energy transfer. MORE
Tecan brings you HP Direct Digital Titration
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Associate Director, CMC Operations
Biotie Therapies
USA – CA – South San Francisco

DNA Assembly Process Lead
Ginkgo BioWorks
USA – MA – Boston

Clinical Laboratory Scientist Team Leader
Cedars-Sinai Medical Center
USA – CA – Los Angeles

More jobs at SLAS Career Connections






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Precision System Science Latest Innovations

Announcing geneLead® Fully Automated Real Time PCR system and Next Gen Sequencing size selection and chemical shearing reagents on the 8G Compact.

Ten Research-Packed Issues Annually

JBS is the leading peer-reviewed journal focused on drug discovery sciences.

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