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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit December 24, 2014    SLAS2015    Moving? New job? Let SLAS know.    






The SLAS Electronic Laboratory Neighborhood

Interactive e-zine sharing experiences and perspectives on science-related topics. Send article ideas to




SLAS ELN Reports: Integrated Impact — The 2014 SLAS Annual Report
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SLAS began 2014 by implementing ambitious plans for a regionalized leadership structure to help foster global growth for the Society.

By the close of 2014, three regional Councils are actively engaged in successfully customizing SLAS's reach and impact in the Americas, Europe and Asia, making it more convenient for life sciences R&D professionals everywhere to Come Transform Research!

Learn more about the year's accomplishments in the SLAS Electronic Laboratory Neighborhood e-zine.


Three New Members Join SLAS Board of Directors
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Welcome Scott Atkin, managing director, SAGIAN Ventures; Michele Cleary, executive director, Merck; and Sue Lunte, professor of chemistry and pharmaceutical chemistry at the University of Kansas, to three-year terms on the SLAS Board of Directors. Atkin, Cleary and Lunte together bring a host of knowledge, experience and industry connections to their new roles on the SLAS Board of Directors.

They will fill vacancies created as Frank Fan, Robyn Rourick and Daniel G. Sipes complete their terms. Read the full release.

TODAY: Last Day to Enter to Win $500 Amazon Gift Card and SLAS2016 Registration in the JALA & JBS Art of Science Contest
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Submit your image by 10:00 p.m. U.S. central time Dec. 24 and you may be a winner!

Click MORE for details.


SLAS2015 Keynote Speaker Francis Collins:
Alzheimer's-in-a-Dish: New Tool for Drug Discovery

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"Researchers want desperately to develop treatments to help the more than 5 million Americans with Alzheimer's disease and the millions more at risk," notes Francis Collins in his Dec. 9 blog as he reports on a Massachusetts General Hospital team that found success when adding a third dimension to their disease model.

As director of the National Institutes of Health, Collins regularly sees results from those funded by the agency. He will share the latest in his Wednesday morning, Feb. 11, keynote address at SLAS2015 in Washington, DC, "Exceptional Technologies and the Transformation of Biomedicine."

SLAS Asia Offers Seminar Jan. 23 in Beijing
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Systemic Screening of Natural Products Targeting Multiple-Targets and Discovery of Drug Candidates is the next SLAS Asia Seminar to be held Friday afternoon, Jan. 23, at the Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences in Beijing. The program features:

Du Guanhua, Academy of Materia Medica, Chinese Academy of Medical Science; Institute of Materia Medica, Chinese Academy of Medical Science; Chinese Pharmacological Society; The National Centre for Drug Screening (Beijing)

Ye Qizhuang, Thousand Talents Program; formerly with Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Shuyi Si, SLAS Asia Council member; Vice Chair of SLAS Asia Education Advisory Committee vice chair; National Center for Screening New Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences

Dai Huanqing, Institute of Microbiology, Chinese Academy of Sciences

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    Why Your Employer Should Reward You for Publishing Your Work in JALA and JBS
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    We've got five good reasons why you should share your achievements with the laboratory science and technology community by publishing in SLAS's two official, rigorously peer-reviewed, MEDLINE-indexed journals. Scientific manuscripts are accepted on an ongoing basis from SLAS members and nonmembers. In addition, manuscript proposals for the following special issues are being accepted now: More

    Next Week: Top 10 SLAS Point-to-Point Stories of 2014
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    In a special end-of-the-year edition of this weekly e-mail news brief, the Dec. 31 issue will look back at the most-popular articles published in SLAS Point-to-Point throughout the past year.

    It's been a great 52 weeks!



    Happy Holidays from SLAS!
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    Even scientists have to admit it's a magical time of the year! As a community of scientists and supporters of science, we deal in fact and reason.

    However, at this time of year, fact and reason often make way for awe and wonder. The leadership and professional teams of SLAS wish you and yours much awe and wonder this holiday season.

    We are constantly amazed by the generous, diverse and inspiring group of people that is the SLAS global community. Above all else, we are grateful that we are able to serve and support you. Happy holidays and happy new year from SLAS!


    Aptamer-Controlled Reversible Inhibition of Gold Nanozyme Activity for Pesticide Sensing
    Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    This study addresses the need for rapid pesticide (acetamiprid) detection by reporting a new colorimetric biosensing assay. Our approach combines the inherent peroxidase-like nanozyme activity of gold nanoparticles (GNPs) with high affinity and specificity of an acetamiprid-specific S-18 aptamer to detect this neurotoxic pesticide in a highly rapid, specific, and sensitive manner. More

    It's All About Your Data
    During SLAS, visit CDD (Booth 1155) to see how you can effortlessly store, analyze, & mine your biological study data & chemical structures with CDD Vault®. Finally, a modern approach to drug research informatics. Click here!

    New Class of Synthetic Molecules Mimics Antibodies    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    A Yale University lab has crafted the first synthetic molecules that have both the targeting and response functions of antibodies. The new molecules — synthetic antibody mimics (SyAMs) — attach themselves simultaneously to disease cells and disease-fighting cells. The result is a highly targeted immune response, similar to the action of natural human antibodies. More

    Glycan Imaging in Intact Rat Hearts and Glycoproteomic Analysis Reveal the Upregulation of Sialylation during Cardiac Hypertrophy
    Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    In the heart, glycosylation is involved in a variety of physiological and pathological processes. Cardiac glycosylation is dynamically regulated, which remains challenging to monitor in vivo. Here we describe a chemical approach for analyzing the dynamic cardiac glycome by metabolically labeling the cardiac glycans with azidosugars in living rats. More

    Tackling One of The Biggest Questions in Dementia Research
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    Researchers in Southampton, United Kingdom, are tackling one of the biggest questions in dementia research; why might current approaches in Alzheimer's trials be failing? The new study is published in the Journal of Pathology and funded by Alzheimer's Research UK and the Medical Research Council. The researchers, led by Dr Delphine Boche at the University of Southampton, wanted to understand the results of a clinical trial that took place over a decade ago. More

    Nanoparticle Sensor Rapidly Profiles Anticancer Drugs
    Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    Scientists at the University of Massachusetts-Amherst say they have developed a multichannel sensor technique using gold nanoparticles that can accurately profile various anticancer drugs and their mechanisms in minutes. As Vincent Rotello, Ph.D., explains, to discover a new drug for any disease, researchers must screen billions of compounds, which can take months. More

    Study Suggests Academic Press Releases May Exaggerate Health Research Claims
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    In the study, published in the BMJ, researchers from Cardiff University found that 40 percent of the press releases they looked at contained exaggerated advice. They added that 33 percent (26 percent to 40 percent) contained exaggerated causal claims, and 36 percent (28 percent to 46 percent) contained exaggerated inference to humans from animal research. More

    The Simplest Element: Turning Hydrogen into 'Graphene'
    Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    New work from Carnegie's Ivan Naumov and Russell Hemley delves into the chemistry underlying some surprising recent observations about hydrogen, and reveals remarkable parallels between hydrogen and graphene under extreme pressures. Their work is the cover story in the December issue of Accounts of Chemical Research. More


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