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SLAS wishes its members and the global life sciences discovery and technology community all the best for 2019! Enjoy this look back at the most-read SLAS Point-to-Point articles of 2018. We resume regular weekly publication on Jan. 2, 2019.
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SLAS
From Feb. 14: 
SLAS Discovery Editor-in-Chief Robert M. Campbell (Eli Lilly & Company) and SLAS Technology Editor-in-Chief Edward Kai-Hua Chow (National University of Singapore) were busy at SLAS2018. They greeted prospective authors in the SLAS Journals Information Station and shared a step-by-step overview of how to design and write scientific research papers more clearly and effectively to improve their chances for publication.
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SLAS
From Feb. 14: 
Paul Ju Sung Hung, Ph.D., chief executive officer of COMBiNATi, Palo Alto, CA, took home top honors and $10,000 for his SLAS2018 presentation "Microfluidic Siphoning Array (MSA) — A Novel Scalable Digital PCR Integrated Platform." In his presentation, Hung described the advantages enabled by this platform, which include lowering both the workflow and cost barriers of digital PCR without compromising the performance in precision and sensitivity. In addition to the cash award, Hung receives an SLAS Premier membership, is invited to have his work featured in either SLAS Discovery or SLAS Technology and joins the judging panel for the 2019 SLAS Innovation Award.
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SLAS
From Jan. 31: 
"The 2018 SLAS Technology Ten represent some of the most innovative scientific achievements that were featured in SLAS Technology in the past 12 months," says Editor-in-Chief Edward Kai-Hua Chow, Ph.D., (National University of Singapore). "SLAS is proud and appreciative that the 83 authors who contributed to the 2018 SLAS Technology Ten for their hard work, ingenuity, and willingness to stretch the boundaries of what is possible in life sciences and biomedical technology." Read more about the 10 honorees in Chow's editorial in the February 2018 issue.
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SLAS
From March 21: 
Hugo Sinha, a master's student in the Department of Electrical and Computer Engineering at Concordia University (Montreal, Canada), is hoping to make automated CRISPR technology accessible to as many cancer researchers as possible. His vision is to "empower all cancer biologists to be able to program their gene editing experiments on their own benchtop instruments." For a closer look at his work in an SLAS Electronic Laboratory Neighborhood e-zine feature article,
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SLAS
From Feb. 7: 
SLAS Discovery and SLAS Technology celebrate honorees in three categories — Readers Choice, Authors Choice and Reviewer Excellence. The 2018 SLAS Journal Achievement Awards reflect popularity of published articles with readers and authors throughout 2017 and exceptional volunteer service in 2017. All articles are now freely available at SLAS Discovery Online and SLAS Technology Online.
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Explore the best combination of kits and instruments to ensure gentle and fast isolation of primary cells for your drug discovery and in vitro assays. Curious? Watch our video on high-throughput cell isolation using the MultiMACS™ X Cell Separator for maximum efficiency and reproducibility.
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SLAS
From June 20: 
A new and free-to-access (for a limited time) SLAS Discovery review article by GlaxoSmithKline researchers in the U.K. and U.S., offers an informative guide to the established and emerging tools available for early drug discovery and screening. The article also provides illustrative scenarios demonstrating considerations that drive decisions on choice of lead discovery tactics. Image courtesy of Melanie Leveridge.
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SLAS
From Sept. 12: 
A new review that can be accessed for free for a limited time in SLAS Discovery, explores how improved safety screening strategies and methods are improving the pharmaceutical discovery and development process. Terry R. Van Vleet et al. of AbbVie (Chicago, IL, USA) outline several fundamental methods of the current drug screening processes and emerging techniques and technologies that promise to improve molecule selection. In addition, the authors discuss integrated screening strategies and provide examples of advanced screening paradigms.
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SLAS
From June 13: 
In a new SLAS Discovery original research article available now for free ahead-of-print, researchers from the Genomics Institute of the Novartis Research Foundation (GNF) highlight a diversity of approaches that their automated high-throughput flow cytometry has enabled for phenotypic drug discovery. Flow cytometry is a very powerful tool that has been used for decades and allows for multiparametric readouts at the single cell level within heterogeneous cell populations. However, in the context of high-throughput screening, flow cytometry is slow, low-throughput, and is not amenable to automation. The GNF group has developed a fully automated screening system that solves this problem.
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SLAS
From June 13: 
In a new SLAS Technology original research article available now for free ahead-of-print, researchers in Switzerland describe the development of a novel screening platform with automated production of 3D muscle- and tendon–like tissues using 3D bioprinting. The novelty and importance of this new approach is the combination of the automated musculoskeletal tissue production using 3D bioprinting with a new microwell plate addressing the specific tissue attachment requirements. Thus, this screening platform represents a promising new tool for musculoskeletal drug discovery and development. Image courtesy of Zurich University of Applied Sciences (ZHAW).
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SLAS
From April 25: 
2018 SLAS Innovation Award Winner Paul Hung, Ph.D., started out as an electrical engineer, but halfway through his graduate studies at the University of California, Berkeley, he switched to bioengineering. "I was fascinated by how many unsolved problems and unlimited possibilities there were in biology and hoped that my engineering expertise could help," says Hung, a serial entrepreneur, and now the CEO of COMBiNATi. A new article in the SLAS Electronic Laboratory Neighborhood (SLAS ELN) reveals how Hung saw "huge potential in the field of genomics" and earned the award for his presentation, "Microfluidic Siphoning Array: A Novel Scalable Digital PCR Integrated Platform."
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