ASCLS eNewsBytes
Nov. 24, 2009

The increasing importance of clinical lab scientists
European Hospital
Clinical laboratory scientists, the medical technologists of the 21st century, are not only enjoying a rapidly expanding role in clinical work but are also increasingly undertaking non-clinical duties such as consultation, quality assurance, laboratory management, professional advocacy and education. It is because rapid access to test results is so crucial for diagnosis, treatment decisions and patient care that clinical laboratories have been in the forefront of computerized health care.More

Use of cardiac markers in the emergency department
eMedicine via Medscape
The role of cardiac markers in the diagnosis, risk stratification, and treatment of patients with chest pain and suspected acute coronary syndrome has continued to evolve. The clinical evaluation of patients with possible acute coronary syndrome is often limited by atypical symptoms. In most patients, the initial electrocardiogram is nondiagnostic. Despite increased vigilance on the part of emergency physicians and high admission rates to exclude acute myocardial infarction, the rate of missed myocardial infarction continues to hover at 1.5-2 percent.More

Drive-thru lab
The Scientist
It's a cloudy May afternoon in the Bronx, and cell biologist Ben Dubin-Thaler is standing in his cramped 1974 General Motors "Fishbowl" bus with a small group of seventh graders, ready to talk microscopy. "The first slide we're going to look at is an onion skin," he says to the group. "Now, who can draw what a plant cell looks like?" One student eagerly raises his hand and proceeds to draw a near-perfect rectangle on the mini-whiteboard to indicate the cell wall. More

Blood supply not affected by H1N1
USA Today
Except for scattered cancellations of high school blood drives because of high absenteeism, the H1N1 pandemic doesn't seem to have had much of an impact on the nation's blood supply. No case of seasonal flu transmitted through a blood transfusion has ever been reported anywhere in the world, according to a draft guidance issued by the Food and Drug Administration. And so far, the FDA says, the same goes for H1N1 flu.More

New research shows versatility of amniotic fluid stem cells
Science Daily
For the first time, scientists have demonstrated that stem cells found in amniotic fluid meet an important test of potential to become specialized cell types, which suggests they may be useful for treating a wider array of diseases and conditions than scientists originally thought.More

An altered pattern of liver Apolipoprotein A-I isoforms is implicated in male chronic hepatitis B progression
The Journal of Proteome Research
Chronic hepatitis B appears to progress more rapidly in males than in females, and CHB-related hepatic cirrhosis and hepatocellular carcinoma are predominately diseases that tend to occur in men and postmenopausal women. To obtain more insight into the underlying mechanisms of gender disparity of CHB progress, two-dimensional difference gel electrophoresis was employed to compare liver proteome of C57BL/6 and HBV transgenic (HBV-Tg) mice both in male and female groups.More

Study: RTLS technology can save hospitals time and money, boost care
Healthcare IT News
A study of the use of a real-time location system at Southeastern Regional Medical Center Lumberton, N.C., indicates the technology can save hospitals hundreds of thousands of dollars a year, improve clinical outcomes and boost staff morale. Another benefit noticed, was in improved clinical outcomes – driven by increased operational efficiency.More

Children's hearing loss from cisplatin chemotherapy associated with gene variants
Medscape Medical News
Scientists at the University of British Columbia, Vancouver, Canada, have identified genetic variants associated with ototoxicity that occur in more than half of children treated with cisplatin. The report, published in Nature Genetics, raises the possibilities that individuals at higher genetic risk for ototoxicity could receive lower cisplatin doses, alternative drug treatments, or be chosen for otoprotectant studies.More

Researchers track down protein responsible for chronic rhinosinusitis with polyps
Medical News Today
A protein known to stimulate blood vessel growth has now been found to be responsible for the cell overgrowth in the development of polyps that characterize one of the most severe forms of sinusitis, a study by Johns Hopkins researchers suggests. The finding gives scientists a new target for developing novel therapies to treat this form of the disease, which typically resists all current treatments.More