This message was sent to ##Email## To advertise in this publication please click here May 8, 2023 To view email in web browser, click here. Liver Transplant Survivor's Recovery Linked to Sociodemographic Factors, Study Shows Medical Xpress The resilience and coping abilities of patients who've had liver transplants vary and change over time and are often linked to sociodemographic factors including income, race and education, a study led by UT Southwestern Medical Center researchers shows. The findings could lead to tailored interventions to optimize clinical and patient-centered outcomes among liver transplant recipients. READ MORE .SOCIETY NEWS Brand-New Conference: Normothermic Regional Perfusion (NRP) ASTS Saturday, June 3 | 7 a.m. - 12 p.m. PT Mark your calendars for a brand-new conference in San Diego, CA! Join experts in the field at this half-day event will discuss important issues related to normothermic regional perfusion (NRP). LEARN MORE AND REGISTER Register Today for the American Transplant Congress ASTS June 3 - 7, 2023 Join us in beautiful San Diego for the American Transplant Congress (ATC)! Register today to learn more about the cutting-edge advances in research and exchange ideas and insights with your colleagues and peers. READ MORE .TOP NEWS The Expanded Role of the Transplant Pharmacist: A Ten Year Follow-up American Journal of Transplatation The role of the transplant pharmacist is recognized by transplant programs, governmental groups and professional organizations as an essential part of the transplant multidisciplinary team. This role has evolved drastically over the last decade with the advent of major advances in the science of transplantation and the growth of the field that necessitate expanded pharmacy services to meet the needs of patients. READ MORE Millions Are Willing to Donate Organs, but Relatively Few Do. Here's Why The Lawton Constitution The scene at OneLegacy in Asuza on a recent Friday morning would have been familiar to anyone who's been in a hospital intensive care unit. Three adults were tucked into hospital beds, still and apparently asleep, with ventilators and other machines of artificial life doing the work that their bodies couldn't do. If you didn't know better, you'd think all the tubes and wires and boxes and screens were designed to save the lives of these patients, but it was too late for that. READ MORE  SPONSORED VIDEO Kidney Transplant Patients and Immunosuppression Now you can see the different ways that different formulations are released and absorbed in the gastrointestinal system. You’ll also have the opportunity to explore comparative pharmacokinetic results in rapid metabolizers, efficacy data over 2 years, and safety information. WATCH VIDEO Deaths From Alcohol-Related Liver Disease Soared During COVID-19 The Harvard Gazette During the pandemic, deaths from alcohol-associated liver disease for American Indian and Alaska Native populations was six times higher than that of white people, according to a study by Massachusetts General Hospital. The study was published in JAMA Health Forum. READ MORE Microvascular Inflammation in the Absence of Human Leukocyte Antigen-Donor-Specific Antibody and C4d: An Orphan Category in Banff Classification With Cytotoxic T and Natural Killer Cell Infiltration American Journal of Transplantation Isolated microvascular inflammation without HLA donor-specific antibodies or C4d deposition in peritubular capillaries remains an enigmatic phenotype that cannot be categorized as antibody-mediated rejection in recent Banff classifications. We included 221 kidney transplant recipients with biopsies with ABMR (n = 73), iMVI (n = 32), and normal (n = 116) diagnoses. We compared peripheral blood leukocyte distribution by flow cytometry and inflammatory infiltrates in kidney transplant biopsies among groups. READ MORE  SPONSORED CONTENT Promoted by Natera Groundbreaking new dd-cfDNA results from the Trifecta Study Combining donor-derived cell-free DNA fraction and amount to detect kidney transplant rejection New findings from the landmark Trifecta Study just published in Transplantation Newly published in Transplantation: the Trifecta Study New donor-derived cell-free DNA results from the Trifecta Study FDA Fast Track for Memo's Kidney Transplant Infection Treatment Labiotech Memo Therapeutics AG, a biotech company developing therapeutic antibodies, says the U.S. Food and Drug Administration has granted fast track designation to AntiBKV, MTx's lead antibody therapeutic that targets the BK polyomavirus infection commonly seen in renal transplant patients. AntiBKV has successfully completed a phase I clinical study and, following FDA clearance, has started actively recruiting patients for a pivotal phase II/III clinical trial. READ MORE Comparison of Two Donor-Derived Cell-Free DNA Tests and a Blood Gene-Expression Profile Test in Heart Transplantation Clinical Transplantation Donor-derived cell-free DNA testing is an emerging screening modality for noninvasive detection of acute rejection. This study compared the testing accuracy for AR of two commercially available dd-cfDNA and gene-expression profiling testing in heart transplant recipients. READ MORE  PRODUCT SHOWCASE Kidney Transplant Tolerance Clinical Trial The FREEDOM-1 Phase 3 clinical trial is evaluating FCR001, an investigational cell therapy with the potential to induce durable immune tolerance without the need for chronic immunosuppression across all levels of HLA mismatch. FREEDOM-1 is now enrolling de novo living donor kidney transplant patients. LEARN MORE Effect of Vitamin K Supplementation on Serum Calcification Propensity and Arterial Stiffness in Vitamin K-Deficient Kidney Transplant Recipients: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial American Journal of Transplantation Vitamin K deficiency is common among kidney transplant recipients and likely contributes to progressive vascular calcification and stiffness. In this single-center, randomized, double-blind, placebo-controlled trial, we aimed to investigate the effects of vitamin K supplementation on the primary end point, serum calcification propensity, and secondary end points arterial stiffness and vitamin K status in 40 vitamin K-deficient KTRs. READ MORE Legislators Reintroduce Bill to Protect Organ Donors Healio A bill aimed at eliminating discrimination against individuals who are turned down for life, disability and long-term care insurance because they are organ donors has been reintroduced in Congress. The Living Donor Protection Act of 2023 is similar to previous versions of the bill, which was first introduced in 2012, according to Healio/Nephrology News & Issues sources, and is sponsored this year by Sen. Kirsten Gillibrand, D-NY, and Rep. Jerrold Nadler, D-NY. APPLY  PRODUCT SHOWCASE A Narrower Profile for Broader Possibilities 15% narrower Based on report #RE00142825, Image creation for Signia™ small diameter reload. March 26, 2019. Compared to the Ethicon Echelon Flex™* powered vascular stapler with advanced placement tip. LEARN MORE CT Volumetry Can Be Used for Monitoring Liver Function Recovery in Auxiliary Partial Orthotopic Liver Transplantation Transplantation Scintigraphy with a 99mTC-trimethyl-Br-IDA tracer is used to monitor liver function regeneration after auxiliary partial orthotopic liver transplantation for acute liver failure. As computed tomography is also regularly performed during patient follow-up, CT volumetry could be used as an alternative to monitor native liver recovery after APOLT for ALF. READ MORE Drone-Delivered Lungs Are a Game-Changer for Organ Transplant Science Boing Boing In September 2022, a groundbreaking drone test in Canada successfully delivered lungs for transplant, marking a game-changing moment for organ transplant science. The drone transported the human donor lung in just five minutes, compared to 25 minutes by road. This achievement suggests that drone delivery could be especially beneficial for organs like hearts and lungs with shorter tolerable times on ice. READ MORE Surgical Treatment of Hepatocellular Carcinoma: Multicenter Competing-Risk Analysis of Tumor-Related Death Following Liver Resection and Transplantation Under an Intention-To-Treat Perspective Transplantation Early-stage hepatocellular carcinoma could benefit from upfront liver resection or liver transplantation, but the optimal strategy in terms of tumor-related outcomes is still debated. We compared the oncological outcomes of LR and LT for hepatocellular carcinoma, stratifying the study population into a low-, intermediate- and high-risk class according to the risk of death at 5-y predicted by a previously developed prognostic model. The impact of tumor pathology on oncological outcomes of low- and intermediate-risk patients undergoing LR was investigated as a secondary outcome. READ MORE  FEATURED ARTICLE   Financial support for kidney transplant patients Promoted by Veloxis Pharmaceuticals Immunosuppressive medications can be a financial burden for kidney transplant patients, potentially costing as much as $10,000 to $14,000 a year. These expenses can have a negative impact on patients’ lives and may play a role in medication nonadherence, which is associated with transplant failure. Learn more about support that is available with a free 30-day trial to allow your patients to start immediately at no cost. And, for patients who are eligible with commercial insurance coverage, a $0 co-pay card offers significant savings. LEARN MORE   Cedars-Sinai Performs a Record-Setting Number of Solid Organ Transplants in 2022 News-Medical Cedars-Sinai is reporting a record-setting year for calendar year 2022. Together, surgeons at the Cedars-Sinai Comprehensive Transplant Center and Smidt Heart Institute performed 583 solid organ transplants during calendar year 2022, surpassing 2021's record of 573 transplants and establishing a new benchmark for the medical center. READ MORE  SPONSORED VIDEO Disparities in Kidney Transplantation: By the Numbers Learn more about disparities in kidney transplantation faced by underrepresented minorities. The future of transplantation starts with you - the providers. As your partner in transplant, we proudly stand by your side. To learn more and access a downloadable infographic PDF, please visit the Sanofi AST PartnerConnect page. © 2021 sanofi-aventis U.S. LLC. All rights reserved. MAT-US-2106427-v1.0-07/2021 WATCH VIDEO Study Suggests Fixes for Persistent Geographic Inequity in Liver Transplants Maryland Today The recent overhaul of the federal policy on allocating deceased donor livers has not significantly improved geographical inequities yet has led to a greater loss in viable organs, according to a new study co-authored by University of Maryland researchers. They recommend improving the broader sharing approach outlined in the 2020 policy, known as Acuity Circles, to mitigate inequities across regions of the country; these include variations in transplant rates, patient survival rates, waiting times and organ offers. READ MORE PRODUCT SHOWCASE Experience Uncompromised Exposure The Thompson Retractor delivers like no other. We understand exposure is key to the success of this procedure. That’s why we’re with you every step of the way with the right design - and the most dedicated team in the business. There’s just one choice. And it’s a great one.   LEARN MORE   Reach Your Prospects Every Week Thousands of industry professionals subscribe to association news briefs, which allows your company to push messaging directly to their inboxes and take advantage of the association's brand affinity.     LEARN MORE   BK Virus Treatment for Renal Transplant Patients Gets Fast Track Status MPR The Food and Drug Administration has granted Fast Track designation to AntiBKV, an investigational antibody therapeutic that targets BK polyomavirus infection in kidney transplant recipients. BKV infection can pose a significant threat to immunocompromised individuals such as renal transplant patients, resulting in impaired graft function and premature transplant loss. READ MORE The Leading dd-cfDNA Test in Transplant AlloSure is the only dd-cfDNA test validated for long-term transplant surveillance LEARN MORE Sociodemographic Factors Linked to Liver Transplant Recovery Hep Magazine A study led by UT Southwestern Medical Center found that the resilience and coping abilities of people who have had liver transplants may evolve over time according to sociodemographic factors, such as race, income and education, reports a UTSMC news release. READ MORE   ASTS News Brief Connect with ASTS Hailey Golden, Director of Publishing, Multiview, 469-420-2630 | Download media kit Mary Todd Anthony, Content Editor, Multiview, 972-373-2013  | Contribute News American Society of Transplant Surgeons 1401 S. Clark St., Suite 1120  |  Arlington, VA 22202   703.414.7870  |  Contact Us  |  asts.org Click here to unsubscribe.  Learn how to add us to your safe sender list so our emails get to your inbox. ADVERTISE SUBSCRIBE PAST ISSUES   7701 Las Colinas Ridge, Ste. 800, Irving, TX 75063