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August 12, 2024

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TOP NEWS

Enhancing Liver Transplant Outcomes Through Donor Interventions
Current Opinion in Organ Transplantation
Donor risk factors and donation events impact liver transplant graft quality. Interventions, particularly in brain death and circulatory death donors, aim to mitigate these risks. Critical care and specific treatments in DBD donors can improve outcomes. Limiting warm ischemia in DCD donors is crucial. For living donors, dietary, exercise programs and minimally invasive surgeries enhance donation outcomes. Read More

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SOCIETY NEWS

2024 Transplant Surgeon Demographic Workforce Census
We need your input to understand the current job market in the U.S. for transplant surgeons! Your responses will provide a snapshot of the current state of the job market and help us forecast for the future. Take the 2-minute survey: https://www.surveymonkey.com/r/7J6DJHR

Submit Your Abstracts to the Winter Symposium
ASTS
Deadline: September 9
Presenting your research is a foundational aspect of the Winter Symposium. By submitting your abstract, you're contributing to the collective knowledge of our members, you'll build strong connections with other transplant professionals, and you're getting your research in front of top experts in the field!
 Learn More

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Give your patients a dose they can manage
Promoted by Veloxis Pharmaceuticals
Your patients probably have a lot to manage after their kidney transplant. Help them with a management strategy they can follow. Read More

INDUSTRY NEWS

Subthreshold Rejection Activity Found in Many Kidney Transplant Biopsies
American Journal of Transplantation
A study of 5,086 kidney transplant biopsies revealed that subthreshold T cell-mediated and antibody-mediated rejection activity exists in many cases classified as no rejection. Elevated molecular classifier scores were found, indicating potential future rejection. This unrecognized activity correlates with increased risk of graft loss and other complications, suggesting the need for more precise monitoring and diagnosis. Read More

UW Faculty to Develop Test Detecting Key Factor in Kidney Transplant Rejection
University of Wisconsin-Madison, Department of Surgery
University of Wisconsin-Madison transplant faculty are developing a test to detect a significant contributor to kidney transplant rejection. The project aims to improve post-transplant outcomes by identifying early signs of rejection, allowing for timely interventions and better management of transplant patients. Read More

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Impact of Size Matching on Survival Post-Heart Transplant in Infants: Estimated Total Cardiac-Volume Ratio Outperforms Donor-Recipient Weight Ratio
Journal of Heart and Lung Transplantation
Cardiac volume-based estimation offers an alternative to donor-recipient weight ratio in pediatric heart transplantation but has not been correlated to posttransplant outcomes. We sought to determine whether estimated total cardiac volume ratio is associated with HT survival in infants. Read More

Kidney Transplants Reduce Depression Risk Compared to Dialysis
Renal and Urology News
A study of 19,806 end-stage kidney disease patients found lower depression and suicide rates in kidney transplant recipients compared to dialysis patients. The dialysis group had a higher incidence of depression (22.8% vs 8.6%) and suicide (0.19% vs 0.12%) than transplant recipients. Read More

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How Dr Sanjeev Akkina and Dr. Jessica Coleman approach the continuity of transplant recipient care with their Prospera surveillance protocols
How Dr. Sanjiv Anand’s experience in the ProActive Study informed his center’s Prospera surveillance protocol
How Dr German Lozano-Guzman introduced a Prospera surveillance protocol to his pediatric transplant program
How Dr Rodolfo Batarse diagnosed ABMR despite a negative biopsy - from his routine ProsperaTM protocol
Promoted by Natera

Gastroenterologist Weighs Pros and Cons of Liver Transplant
News9 Live
Liver transplants can save lives but come with risks. Benefits include prolonged life and improved health. However, cons involve surgical risks, potential for rejection and lifelong immunosuppressive therapy. Patients must weigh these factors with their healthcare providers to make informed decisions. Read More

Expanding Split Liver Transplants Could Save More Lives
STAT
Split liver transplantation can save two lives from a single donor. Despite its potential, barriers remain. Jacob's story exemplifies its success: receiving 40% of a liver while Miranda got 60%. Expanding this practice could help the 2,400 Americans who die waiting for a liver transplant each year. Read More

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A Tailored Virtual Program for Alcohol Use Disorder Treatment Among Liver Transplant Candidates and Recipients Is Feasible and Associated With Lower Post-Transplant Relapse
Clinical Transplantation
Alcohol-associated liver disease is a leading indication for liver transplant in the U.S. Rates of early liver transplant with less than six months of sobriety have increased substantially. Read More

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Study: MASLD, MetALD Cause One-Third of ICU Cirrhosis Cases
Medical Xpress
A study found that one-third of ICU cirrhosis cases are due to MASLD and MetALD. MASLD patients were older with lower scores on liver disease severity scales. Despite similar transplant-free survival rates, MASLD patients had higher risks of developing hepatic encephalopathy. The study suggests rapid liver transplantation discussions for severe cases. Read More

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Looking for immunosuppression data?
Promoted by Veloxis Pharmaceuticals

Efficacy and safety are important when it comes to immunosuppression after kidney transplantation. Explore clinical data to learn more about the efficacy and safety of your immunosuppression options. Explore the clinical data

Bravery Leads to Life-Saving Liver Transplant for 6-Year-Old
Spectrum News
Lucy Sughroue, a 6-year-old diagnosed with PFIC 2 and liver cancer, received a life-saving liver transplant. Despite challenges, she now thrives a year post-surgery, thanks to a donor match found within a month. Her journey emphasizes resilience and bravery in overcoming illness. Read More

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Promoted by sanofi
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Learn more about disparities in kidney transplantation faced by underrepresented minorities.

The future of transplantation starts with you - the providers. As your partner in transplant, we proudly stand by your side.

To learn more and access a downloadable infographic PDF, please visit the Sanofi AST PartnerConnect page.

© 2021 sanofi-aventis U.S. LLC. All rights reserved. MAT-US-2106427-v1.0-07/2021
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Evaluating COVID-19 Vaccination Efficacy in Solid Organ Transplant Recipients
American Journal of Transplantation
A systematic review and network meta-analysis assessed the efficacy and safety of COVID-19 vaccination in solid organ transplant recipients, incorporating data from six RCTs and 43 observational studies. The evidence, primarily nonrandomized, indicated low to very low certainty regarding vaccine impact on infection, mortality, hospitalization, ICU admission and rejection due to biases. The review highlights the need for higher-quality research in future public health emergencies to better support this vulnerable population. Read More

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Liver Transplant Boosts Progression-Free Survival in Colorectal Metastasis Patients
Medscape
Liver transplants significantly improved progression-free survival in patients with unresectable colorectal liver metastasis, with higher PFS rates at 1, 2 and 3 years compared to alternative therapies. Despite better overall survival and lower recurrence rates in the transplant group, these benefits did not reach statistical significance, possibly due to the small sample size. Read More

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The Leading dd-cfDNA Test in Transplant
Promoted by CareDx
AlloSure is the only dd-cfDNA test validated for long-term transplant surveillance. Learn More

Post-Transplant Diabetes Heightens Risk for Kidney Transplant Recipients
Medical Dialogues
Post-transplant diabetes, common in solid organ recipients, significantly raises mortality and morbidity risks for kidney transplant patients. Effective diabetes management, including continuous glucose monitoring, is crucial for these individuals, who face unique challenges like hypoglycemia and limited therapeutic options. Proper screening and tailored treatment plans are vital for improving outcomes. Read More

ASTS News Brief
American Society of Transplant Surgeons
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