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.FSP NEWS
Check Your Mailbox for your Invitation from FSP
FSP
Check your mailbox for your official invitation from the Florida Society of Pathologists to join us for our first-ever virtual edition of the FSP’s Annual Pathology Conference on Feb. 12-14, 2021. The FSP Education Committee has been hard at work producing an educationally impactful and socially enriching virtual conference, no easy feat! With the ability to watch the sessions live and earn up to 12 hours of CME credit, the opportunity to interact with your colleagues and our expert faculty through live question and answer sessions and the chance to catch any of the sessions you missed live through our virtual platform for up to 60 days after the meeting, there is no reason not to participate! To learn more about the meeting and to register online visit the FSP website here.
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FSP Nominating Committee Recommends Slate for 2021-2023
FSP
The FSP Nominating Committee is pleased to announce the recommendations for the new slate of officers for the FSP Board of Directors for the 2021-2023 term. The FSP membership will vote on the slate during the Annual Business Meeting to be held on Sunday, Feb. 14 in conjunction with the 47th Annual Pathology Conference taking place virtually. To read the full report by the Nominating Committee visit the FSP website here.
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.INDUSTRY NEWS
Bleeding disorder linked to poor clinical outcomes in COVID-19 patients
News-Medical.Net
The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the pathogen responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic. Approximately 20-55% of hospitalized COVID-19 patients are reported to have deranged hemostatic laboratory parameters, which suggests coagulopathy.
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Alzheimer's progression tracks with blood biomarkers
MedPage Today
Blood-based biomarkers paralleled the progression of Alzheimer's disease neurodegeneration, a large longitudinal cohort study showed.
Increases of phosphorylated tau at threonine 181 (p-tau181) in blood plasma over time were linked with progressive neurodegeneration in brain regions associated with Alzheimer's disease and cognitive decline in people with elevated brain amyloid-beta (Aβ), reported Michael Scholl, PhD, of University of Gothenburg in Sweden, and colleagues, in JAMA Neurology.
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Tissue stiffness likely drives immune responses in many chronic diseases
EurekAlert
Stiffness in our tissues causes tension in our cells. Research from the Buck Institute, the University Health Network (University of Toronto), Stanford University, and the University of Alberta shows that stiffness impacts the innate immune system by upping its metabolism. The findings suggest the cellular tension likely sets off an inflammatory loop that contributes to the development of chronic diseases of aging. Publishing in Cell Reports, Buck Associate Professor Dan Winer, MD, and colleagues present an emerging way of looking at how the immune system functions, possibilities for new immunotherapeutics, and a call for scientists to reconsider the way they do research.
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How effective are antibodies for treating COVID-19?
News-Medical.Net
As of January 5, 2020, approximately 1.86 million people have died from infection by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This unprecedented global health and economic crisis has led scientists to investigate alternative treatment approaches that might be able to treat and/or prevent the effects of this highly infectious disease, one of which includes monoclonal antibody therapies.
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University of Vermont microbiology laboratory identifies inefficiencies when performing pooled testing for COVID-19
Dark Daily
Experts believe pooled testing for COVID-19 could reduce the number of standard tests for SARS-CoV-2 by conserving testing resources and cutting lab spending on tests and testing supplies. However, some clinical laboratories have found pooled testing causes inefficiencies due to the lab’s lack of staff, limitations of existing equipment, and biosafety hood space, as well as not having a laboratory information system (LIS) that can manage the large volume of specimens and retesting involved in pooled testing.
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Triple-negative breast cancer: Assessing the role of immunohistochemical biomarkers on neoadjuvant treatment
MDLinx
Researchers determined the impact of immunohistochemical biomarkers in the response to neoadjuvant chemotherapy as well as survival results in the subset of locally advanced triple-negative breast cancer. Overall 171 cases of TNBC submitted to NACT and subsequently to surgery participated in this study. In these cases, epidermal growth factor receptor, androgen receptor, cytokeratins (CK5/6, CK14 and CK17), Ki67 and p53 immunohistochemistry were assessed.
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Research shows why COVID pneumonia is more deadly
WebMD
Unlike regular pneumonia, COVID-19 pneumonia spreads like many "wildfires" throughout the lungs, researchers say.
This may explain why COVID-19 pneumonia lasts longer and causes more harm than typical pneumonia, according to the researchers at Northwestern Medicine in Chicago.
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1 in 5 brain cancers fueled by overactive mitochondria
Columbia University Irving Medical Center
A new study has found that up to 20% of glioblastomas — an aggressive brain cancer — are fueled by overactive mitochondria and may be treatable with drugs currently in clinical trials.
Mitochondria are responsible for creating the energy that fuels all cells. Though they are usually less efficient at producing energy in cancer, tumor cells in this newly identified type of glioblastoma rely on the extra energy provided by overactive mitochondria to survive.
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