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.FSP NEWS
Register for Early FSP Virtual and Get a Gift From FSP!
FSP
Register early for our first-ever virtual conference and if you are one of the first 100 attendees to register and you reside in the United States, you will receive a conference swag box from the FSP. A box curated with specialty FSP items will be delivered to your home or office before the start of the virtual meeting. Thank you to Neogenomics Laboratories, Inc. for their gracious sponsorship of the conference swag box. Register early to claim your swag box!
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Attend FSP Business Meeting — Feb.14 at 10:30 am
FSP
The FSP will host a virtual business meeting at the FSP’s 47th Annual Pathology Conference on Sunday, Feb. 14 at 10:30 am ET. The business meeting will update FSP members on current events with a report on FSP finances, an update on membership, a report from the FSP Pathology PAC, and a report from the nominating committee regarding the recommended slate of officers and at-large board members for the 2021-2023 term. There will also be a presentation of awards where the top three winners of the FSP Poster Competition will be awarded and FSP President Dr. Morton Levitt will present his Presidential Service Awards. Attendees will hear remarks from President-Elect, Dr. Qihui “Jim” Zhai as he officially begins his terms as your next FSP President. The business meeting is complimentary and only open to FSP members. To register for the virtual conference, visit the FSP website.
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FSP Member Spotlight — Meet Ali Saad, MD from University of Miami
FSP
This month we are delighted to feature Ali Saad, MD. Dr. Saad is relatively new to the state of Florida and FSP as a Professor and Director at the University of Miami Miller School of Medicine. Dr. Saad’s practice includes pediatric pathology and neuropathology. He also serve as director of Pediatric & Perinatal Pathology Service and director of Pediatric & Perinatal Pathology Fellowship Program. Read Dr. Saad’s full member profile by visiting the FSP website here.
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.INDUSTRY NEWS
FDA guides on COVID considerations in cell and gene therapy
Regulatory Affairs Professionals Society
Manufacturers of cell and gene therapies have a new guidance from the US Food and Drug Administration that provides pandemic-related manufacturing considerations.
The guidance specifically addresses both licensed and investigational cell and gene therapy manufacture, and “is intended to supplement the recommendations to drug and biological product manufacturers provided in FDA’s ‘Good Manufacturing Practice Considerations for Responding to COVID-19 Infection in Employees in Drug and Biological Products Manufacturing; Guidance for Industry’ issued in June 2020,” according to the guidance.
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What is new in the world of imaging?
Drug Target Review
Imaging, in its many forms, is an essential part of life sciences research. It enables researchers to visualize what is hidden by size or many layers of membranes to unearth potential drug targets and, in some cases, explore how drugs targeting them work. In this article find out about some of the latest innovations in imaging that are driving drug target identification and drug development forward.
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Nixing bone cancer fuel supply offers new treatment approach, mouse study suggests
Medical Xpress
An innovative approach to treating bone tumors — starving cancer cells of the energy they need to grow — could one day provide an alternative to a commonly used chemotherapy drug without the risk of severe side effects, suggests a new study from Washington University School of Medicine in St. Louis. Studying human cancer cells and mice, the researchers said that a two-drug combination targeting a tumor's energy sources could be as effective and less toxic than methotrexate, a long-used chemotherapy drug often given in high doses to treat osteosarcoma, a bone cancer.
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Studies extend hopes for antibody drugs against COVID-19
Medical Xpress
New results extend hopes for drugs that supply antibodies to fight COVID-19, suggesting they can help keep patients out of the hospital and possibly prevent illness in some uninfected people. Eli Lilly said recently that a two-antibody combo reduced the risk of hospitalizations or death by 70% in newly diagnosed, non-hospitalized COVID-19 patients at high risk of serious illness because of age or other health conditions. All 10 deaths that occurred in the study were among those receiving placebo rather than the antibodies.
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Brain cells most vulnerable to Alzheimer's disease identified by scientists
UCSF
A major mystery in Alzheimer’s disease research is why some brain cells succumb to the creeping pathology of the disease years before symptoms first appear, while others seem impervious to the degeneration surrounding them until the disease’s final stages. Now, in a study published Jan. 10, 2021, in Nature Neuroscience, a team of molecular biologists and neuropathologists from the UCSF Weill Institute for Neurosciences have joined forces to identify for the first time the neurons that are among the first victims of the disease – accumulating toxic “tangles” and dying off earlier than neighboring cells.
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SARS-CoV-2 rapidly adapts to Vero E6 cell culture propagation
News-Medical.Net
As the coronavirus disease 2019 (COVID-19) pandemic continues to wreak havoc across the globe, scientists race to further understand the virus and how it infects the body. This way, safe and effective therapeutics and other potential preventive measures can be developed to bring surging case-loads across the globe under control.
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Avalanching nanoparticles break barriers to imaging cells in real time
SciTechDaily
Since the earliest microscopes, scientists have been on a quest to build instruments with finer and finer resolution to image a cell’s proteins — the tiny machines that keep cells, and us, running. But to succeed, they need to overcome the diffraction limit, a fundamental property of light that long prevented optical microscopes from bringing into focus anything smaller than half the wavelength of visible light (around 200 nanometers or billionths of a meter) — far too big to explore many of the inner-workings of a cell.
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