Researchers in this study aimed to test the effectiveness of a 32-week, stepped-care intervention on disease remission rates in overweight and obese patients with medial tibiofemoral osteoarthritis (OA) compared to controls.
source: Arthritis Care & Research
Previous studies have identified aberrant chondrocyte homeostasis under extracellular stress as a key pathological mechanism behind cartilage degradation in osteoarthritis (OA). TDP-43, a DNA/RNA-binding protein has been...
source: Osteoarthritis and Cartilage
Researchers aimed to investigate acute changes in biochemical markers of cartilage turnover in response to moderate intensity exercise with and without joint impact in humans with knee osteoarthritis.
source: Osteoarthritis and Cartilage
Some studies have examined the association between dietary factors and risk of knee osteoarthritis (OA). Researchers aimed to examine the prospective association of major dietary patterns with the risk of developing knee OA....
source: Osteoarthritis and Cartilage
In this study, researchers sought to compare progression over eight years in knee compositional cartilage degeneration and structural joint abnormalities in knees with different types of ACL abnormalities over eight years.
source: Osteoarthritis and Cartilage
OARSI's Discussion Groups bring together individuals with a focus on specific OA-related specialty areas. All Discussion Groups will be meeting virtually this spring, either prior to or after OARSI Connect '21. Attendance to the Discussion Group meetings is complimentary...
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April 14, 2021, 9 a.m. ET: Cell and Gene Therapy - Regenerative Medicine. For registration and more information, click here.
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OARSI Connect '21 is just around the corner! For registration...
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In this study, researchers aimed to compare ground reaction force patterns (GRF) during walking among legs defined by presence or absence of knee pain and/or radiographic knee osteoarthritis (ROA).
source: Osteoarthritis and Cartilage
Autoantibodies (AutoAbs) have been observed in osteoarthritis (OA) with broad antigenicity, although their prevalence and role remain unclear. Post-translational modification (PTMs) of proteins (oxidation, carbamylation, citrullination)...
source: Osteoarthritis and Cartilage
April 8, 2021: OARSI Rehabilitation Discussion Group Journal Club Dissecting the "START trial". For event flyer and registration information, click here.
April 28, 2021: OARSI Rehabilitation Discussion Group — Update and poster presentations of digital technology...
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March 31, 2021, 9 a.m. ET: Nuts & Bolts of Writing a Successful Grant: Perspectives from Early Career Investigators. For registration and more information, click here.
April 7, 2021, 9 a.m. ET: The Mechanobiology Path Towards Joint Health. For registration and more information,...
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Registration for OARSI Connect '21 is open! For registration rates...
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In a multicenter, randomized, placebo-controlled, double-blind phase 3 trial, researchers aimed to confirm the efficacy and safety of intra-articular injection of diclofenac covalently linked to hyaluronic acid (diclofenac etalhyaluronate [DF-HA]: ONO-5704/SI-613).
source: Arthritis & Rheumatology
Inflammation worsens joint destruction in osteoarthritis (OA) and aggravates pain. Saturated and n-6 fatty acids (FAs) increase, whereas n-3 FAs reduce inflammation. Researchers examined whether FA levels affected the development of OA.
source: Osteoarthritis and Cartilage