Boyalife, Science and Science Translational Medicine...
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"Is there a formula on how to behave in the workplace?" Whatever your stand on this question, all would likely agree that the tone and quality of interpersonal relationships in the laboratory — whether among trainees and staff or between supervisor and student —...
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A technique that combines gene therapy and magnets could someday provide a new tool for treating cardiovascular disease, which puts millions of lives at risk every year. Researchers have produced cells that carry magnetic nanoparticles linked to a therapeutic gene. With...
source: C&EN
Synthetically engineered biosensors, which can be designed to detect and signal the presence of specific small molecule compounds, have already unlocked many potential applications by harnessing bacterial cells such as E. coli to sense toxins or enable bioproduction of valuable...
source: NanoWerk
Endothelial cells that line capillaries are not just passive conduits for delivering blood. Tissue-specific endothelium establishes specialized vascular niches that deploy sets of growth factors, known as angiocrine factors. These cues participate actively in the induction,...
source: Nature
Cells are covered by a surface layer of glycans that is referred to as the 'glycocalyx'. In this review, we focus on the role of the glycocalyx in vascular diseases (atherosclerosis, stroke, hypertension, kidney disease and sepsis) and cancer. The glycocalyx and its principal...
source: Journal of Internal Medicine
Clinical evidence links arterial calcification and cardiovascular risk. Finite-element modelling of the stress distribution within atherosclerotic plaques has suggested that subcellular microcalcifications in the fibrous...
source: Nature Materials
Over 20% of pregnancies in patients with systemic lupus erythematosus (SLE) and/or antiphospholipid antibodies (APL) result in an adverse pregnancy outcome (APO) related to abnormal placentation....
source: American Journal of Obstetrics and Gynecology
Fibrin deposition and absent endothelium characterize unhealed stents that are at heightened risk of stent thrombosis. Optical coherence tomography (OCT) is increasingly used for assessing stent tissue...
source: European Hearth Journal
Telomerase is a nuclear regulator of telomere elongation with recent reports suggesting a role in regulation of mitochondrial reactive oxygen species (mtROS). Since mtROS (H2O2) mediate flow-mediated dilation (FMD) in the human microcirculation.
source: Circulation Research
The microcirculation is responsible for orchestrating adjustments in vascular tone to match local tissue perfusion with oxygen demand. Beyond this metabolic dilation, the microvasculature plays a critical role in modulating vascular tone by endothelial release of an unusually...
source: Circulation Research
Adipose-derived mesenchymal stem cells (MSCs) have been gaining fame mainly due to their vast clinical potential, simple isolation methods and minimal donor site morbidity. Adipose-derived MSCs and microvascular...
source: Stem Cell Research and Therapy
This month we are highlighting the lab of Dr. Daniel Rifkin of the New York University in New York, New...
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We're looking ahead to Vascular Biology 2017 (October 15-19 at the Asilomar Conference Grounds) and we want your input. The NAVBO Council and the meeting organizers (Vicki Bautch, Brian Black, Craig Simmons and Jessica Wagenseil) are seeking proposals from NAVBO members...
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